中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共407条,第1-10条 帮助

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Catalytic site flexibility facilitates the substrate and catalytic promiscuity of Vibrio dual lipase/transferase 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 11
作者:  
Wang, Chongyang;  Liu, Changshui;  Zhu, Xiaochuan;  Peng, Quancai;  Ma, Qingjun
  |  收藏  |  浏览/下载:8/0  |  提交时间:2023/12/13
Structural analysis of the dual agonism at GLP-1R and GCGR 期刊论文  OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 33, 页码: 12
作者:  
Li, Yang;  Zhou, Qingtong;  Dai, Antao;  Zhao, Fenghui;  Chang, Rulue
  |  收藏  |  浏览/下载:0/0  |  提交时间:2024/05/07
Elastic network models and molecular dynamic simulations reveal the molecular basis of allosteric regulation in ubiquitin-specific protease 7 (USP7) 期刊论文  OAI收割
COMPUTERS IN BIOLOGY AND MEDICINE, 2023, 卷号: 162, 页码: 10
作者:  
Xu, Jing
  |  收藏  |  浏览/下载:17/0  |  提交时间:2023/10/17
A hydrogen-deuterium exchange mass spectrometry-based protocol for protein-small molecule interaction analysis 期刊论文  OAI收割
Biophysics reports, 2023, 卷号: 9, 期号: 2, 页码: 99-111
作者:  
Meng, Qian;  Song, Yuan-Li;  Zhou, Chen;  He, Han;  Zhang, Naixia
  |  收藏  |  浏览/下载:16/0  |  提交时间:2024/03/26
Modular Biomimetic Strategy Enabled Discovery of Simplified Pseudo-Natural Macrocyclic P-Glycoprotein Inhibitors Capable of Overcoming Multidrug Resistance 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 4, 页码: 2550-2565
作者:  
Liu, Bo;  Yu, Xueni;  Liu, Liping;  Wang, Lei;  Wang, Jie
  |  收藏  |  浏览/下载:5/0  |  提交时间:2024/03/27
Discovery and mechanism of action of Thonzonium bromide from an FDA-approved drug library with potent and broad-spectrum inhibitory activity against main proteases of human coronaviruses 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 11
作者:  
Wang, Ruyu;  Zhai, Guanglei;  Zhu, Guanghao;  Wang, Mengge;  Gong, Xiaoyi
  |  收藏  |  浏览/下载:14/0  |  提交时间:2023/04/10
Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation 期刊论文  OAI收割
CELL DISCOVERY, 2022, 卷号: 8, 期号: 1, 页码: 17
作者:  
Xie, Zuoquan;  Wang, Zhen;  Fan, Fengying;  Zhou, Jinpei;  Hu, Zhaoxue
  |  收藏  |  浏览/下载:22/0  |  提交时间:2023/04/10
An optimization algorithm for conformer generation based on the bond contribution ranking 期刊论文  OAI收割
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2022, 卷号: 100, 页码: 107751
作者:  
Zhang, Ziheng;  Zhang, Kai;  Liu, Zhihui;  Zhao, Jialei;  Wang, Jing
  |  收藏  |  浏览/下载:17/0  |  提交时间:2024/03/21
Nanobodies and chemical cross-links advance the structural and functional analysis of PI3K alpha 期刊论文  OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119, 期号: 38, 页码: 9
作者:  
Hart, Jonathan R.;  Liu, Xiao;  Pan, Chen;  Liang, Anyi;  Ueno, Lynn
  |  收藏  |  浏览/下载:12/0  |  提交时间:2023/10/17
Size exclusion chromatography using large pore size media induces adverse conformational changes of inactivated foot-and-mouth disease virus particles 期刊论文  OAI收割
Journal of Chromatography A, 2022, 卷号: 1677
作者:  
Song, Yanmin;  Yang, Yanli;  Lin, Xuan;  Zhao, Qizu;  Su, Zhiguo
  |  收藏  |  浏览/下载:0/0  |  提交时间:2023/06/26