中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
昆明植物研究所 [1]
采集方式
OAI收割 [8]
内容类型
期刊论文 [7]
学位论文 [1]
发表日期
2024 [1]
2022 [1]
2018 [1]
2017 [2]
2015 [1]
2014 [1]
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Discovery of a CB2 and 5-HT1A receptor dual agonist for the treatment of depression and anxiety
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 20
作者:
Yang, Wenjiao
;
Gong, Xudong
;
Sun, Haiguo
;
Wu, Chunhui
;
Suo, Jin
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/03/06
CB2R agonist
5-HT1AR agonist
CB1R antagonist
Antidepressant
Anxiolytic
几种唇形科植物萜类合酶及杂萜gwa-1组合生物合成研究
学位论文
OAI收割
: 中国科学院大学, 2022
作者:
王安
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/14
黄芩
Scutellaria baicalensis
半枝莲
Scutellaria barbata
萜类合酶
Terpenoid synthase
β-石竹烯合酶
β-caryophyllene synthase
大麻素类
Cannabinoid derivatives
Design, Synthesis, and SAR Studies of Heteroarylpyrimidines and Heteroaryltriazines as CB2R Ligands
期刊论文
OAI收割
CHEMMEDCHEM, 2018, 卷号: 13, 期号: 22, 页码: 2455-2463
作者:
Qian, Hai-Yan
;
Wang, Zhi-Long
;
Chen, Li-Li
;
Pan, You-Lu
;
Xie, Xiao-Yu
  |  
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2019/01/08
cannabinoids
CB1R
CB2R
heteroaryl pyrimidines
heteroaryl triazines
ligands
Developing pyridazine-3-carboxamides to be CB2 agonists: The design, synthesis, structure-activity relationships and docking studies
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 598-611
作者:
Qian, Hai-Yan
;
Wang, Zhi-Long
;
Xie, Xiao-Yu
;
Pan, You-Lu
;
Li, Gang-Jian
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Pyridazine-3-carboxamides
CB2 agonist
Structure-activity relationships
Molecular docking
logP
Development of Quinazoline/Pyrimidine-2,4(1H,3H)-diones as Agonists of Cannabinoid Receptor Type 2
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 8, 期号: 6, 页码: 678-681
作者:
Qian, Hai-Yan
;
Wang, Zhi-Long
;
Pan, You-Lu
;
Chen, Li-Li
;
Xie, Xin
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Cannabinoid receptors
CB2 agonist
structure-activity relationship
molecular modeling
Design, syntheses, structure-activity relationships and docking studies of coumarin derivatives as novel selective ligands for the CB2 receptor
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 93, 页码: 16-32
作者:
Han, Shuang
;
Zhang, Fei-Fei
;
Qian, Hai-Yan
;
Chen, Li-Li
;
Pu, Jian-Bin
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
GPCR
Cannabinoid CB2 receptor
Structure-activity relationship
Coumarin
Design, synthesis, biological evaluation, and comparative docking study of 1,2,4-triazolones as CB1 receptor selective antagonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 74, 页码: 73-84
作者:
Han, Shuang
;
Zhang, Fei-Fei
;
Xie, Xin
;
Chen, Jian-Zhong
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Cannabinoid receptors
Antagonist
1,2,4-Triazolone
Scaffold hopping
Homology model
Discovery of benzhydrylpiperazine derivatives as CB1 receptor inverse agonists via privileged structure-based approach
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2010, 卷号: 45, 期号: 3, 页码: 1133-1139
作者:
Meng, Tao
;
Wang, Jue
;
Peng, Hongli
;
Fang, Guanghua
;
Li, Min
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
Benzhydrylpiperazine
Privileged structure
Cannabinoid receptor 1(CB1)
Anti-obesity