中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
大连化学物理研究所 [52]
上海药物研究所 [13]
金属研究所 [2]
深圳先进技术研究院 [1]
水生生物研究所 [1]
生态环境研究中心 [1]
更多
采集方式
OAI收割 [71]
iSwitch采集 [1]
内容类型
期刊论文 [63]
会议论文 [9]
发表日期
2024 [1]
2023 [1]
2022 [3]
2019 [3]
2018 [2]
2017 [5]
更多
学科主题
物理化学 [9]
生物药物学 [1]
药学其他学科 [1]
药物化学 [1]
筛选
浏览/检索结果:
共72条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
提交时间升序
提交时间降序
题名升序
题名降序
作者升序
作者降序
发表日期升序
发表日期降序
Detection of uridine diphosphate glucuronosyltransferase 1A1 for pancreatic cancer imaging and treatment
via
a "turn-on" fluorescent probe
期刊论文
OAI收割
ANALYST, 2024, 页码: 10
作者:
Wang, Lingxiao
;
Wang, Lingyun
;
Sun, Xiao
;
Fu, Lili
;
Wang, Xinlei
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/07
Pharmacokinetics,mass balance,and metabolism of 14C TPN171,a novel PDE5 inhibitor,in humans for the treatment of pulmonary arterial hypertension
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 1, 页码: 221
作者:
He Yifei
;
Liu Yin
;
Yu Jinghua
;
Cheng Huan
;
Odilov Abdullajon
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/05/22
TPN171
14CTPN171
PDE5 inhibitor
pulmonary arterial hypertension
healthy volunteers
pharmacokinetics
metabolite identification
mass balance
Identification of naturally occurring inhibitors in Xian-Ling-Gu-Bao capsule against the glucuronidation of estrogens
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 17
作者:
He, Liangliang
;
Xu, Chunxia
;
Wang, Ziying
;
Duan, Shuyi
;
Xu, Jinjin
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/04/10
Xian-Ling-Gu-Bao capsule
estrogens
glucuronidation
inhibitory effects
UDP-glucuronosyltransferase
Pharmacokinetics, mass balance, and metabolism of [C-14]TPN171, a novel PDE5 inhibitor, in humans for the treatment of pulmonary arterial hypertension
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 13
作者:
He, Yi-fei
;
Liu, Yin
;
Yu, Jing-hua
;
Cheng, Huan
;
Odilov, Abdullajon
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/08/16
TPN171
[C-14]TPN171
PDE5 inhibitor
pulmonary arterial hypertension
healthy volunteers
pharmacokinetics
metabolite identification
mass balance
Pharmacokinetics, Mass Balance, and Metabolism of the Novel Urate Transporter 1 Inhibitor [14C]HR011303 in Humans: Metabolism Is Mediated Predominantly by UDP-Glucuronosyltransferase
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2022, 卷号: 50, 期号: 6, 页码: 798-808
作者:
Zheng, Yuandong
;
Zhang, Hua
;
Liu, Mengling
;
Li, Guangze
;
Ma, Sheng
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/08/16
Per- and polyfluoroalkyl substances display structure-dependent inhibition towards UDP-glucuronosyltransferases
期刊论文
OAI收割
ENVIRONMENTAL POLLUTION, 2019, 卷号: 254, 页码: -
作者:
Liu, Yong-Zhe
;
Zhang, Zhi-Peng
;
Fu, Zhi-Wei
;
Yang, Kun
;
Ding, Ning
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/09/10
Per- and polyfluoroalkyl substances (PFASs)
UDP-Glucuronosyltransferases (UGTs)
Half inhibition concentration (IC50)
Inhibition type
Inhibition kinetic parameters (Ki)
In vitro-in vivo extrapolation (IVIVE)
Recent progress and challenges in screening and characterization of UGT1A1 inhibitors
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 2, 页码: 258-278
作者:
Finel, Moshe
;
Lv, Xia
;
Xia, Yangliu
;
Wu, Jingjing
;
Ge, Guangbo
  |  
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2019/06/20
UGT1A1 inhibitors
Drug/herbdrug interactions
Probe substrates
High-throughput screening
Recent progress and challenges in screening and characterization of ugt1a1 inhibitors
期刊论文
iSwitch采集
Acta pharmaceutica sinica b, 2019, 卷号: 9, 期号: 2, 页码: 258-278
作者:
Lv, Xia
;
Xia, Yangliu
;
Finel, Moshe
;
Wu, Jingjing
;
Ge, Guangbo
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2019/05/08
Ugt1a1 inhibitors
Drug/herbdrug interactions
Probe substrates
High-throughput screening
New Insights into SN-38 Glucuronidation: Evidence for the Important Role of UDP Glucuronosyltransferase 1A9
期刊论文
OAI收割
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2018, 卷号: 122, 期号: 4, 页码: 424-428
作者:
Xiao, Ling
;
Zhu, Liangliang
;
Li, Wenjuan
;
Li, Conghu
;
Cao, Yunfeng
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/06/20
Highly selective N-glucuronidation of four piperazine-containing drugs by UDP-glucuronosyltransferase 2B10
期刊论文
OAI收割
Expert Opinion on Drug Metabolism & Toxicology, 2018
作者:
Danyi Lu
;
Dong Dong
;
Baojian Wu
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/31