中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
化学研究所 [3]
理论物理研究所 [2]
数学与系统科学研究院 [2]
上海生物化学与细胞生... [2]
昆明动物研究所 [2]
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OAI收割 [24]
内容类型
期刊论文 [24]
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2023 [1]
2022 [3]
2020 [3]
2018 [1]
2017 [1]
2016 [3]
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Physics [2]
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Cell Biolo... [1]
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The new direction of drug development: Degradation of undruggable targets through targeting chimera technology
期刊论文
OAI收割
MEDICINAL RESEARCH REVIEWS, 2023, 页码: 54
作者:
Liang, Xuewu
;
Ren, Hairu
;
Han, Fengyang
;
Liang, Renwen
;
Zhao, Jiayan
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/01/16
chimeric design
degradation System
PROTAC
targeted degradation technology
undruggable targets
Dynamic Interactions Between Brilliant Green and MscL Investigated by Solid-State NMR Spectroscopy and Molecular Dynamics Simulations
期刊论文
OAI收割
CHEMISTRY-A EUROPEAN JOURNAL, 2022, 页码: 12
作者:
Ma, Shaojie
;
Zhang, Yan
;
Zhang, Xuning
;
Xie, Huayong
;
Tong, Qiong
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/04/10
Antibiotic
Brilliant Green
mechanosensitive channel of large conductance (MscL)
molecule dynamics simulations
solid-state NMR
Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 12
作者:
Zhuang, Youwen
;
Wang, Lei
;
Guo, Jia
;
Sun, Dapeng
;
Wang, Yue
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/06/15
Chern Fermi pocket, topological pair density wave, and charge-4e and charge-6e superconductivity in kagome superconductors
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 7288
作者:
Zhou, Sen
;
Wang, Ziqiang
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/01/16
FLUX PHASE
ORDER
Binding and Activity of Tetrabromobisphenol A Mono-Ether Structural Analogs to Thyroid Hormone Transport Proteins and Receptors
期刊论文
OAI收割
ENVIRONMENTAL HEALTH PERSPECTIVES, 2020, 卷号: 128, 期号: 10, 页码: 1-10
作者:
Ren, Xiao-Min
;
Yao, Linlin
;
Xue, Qiao
;
Shi, Jianbo
;
Zhang, Qinghua
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/09/14
Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion
期刊论文
OAI收割
ADVANCED SCIENCE, 2020, 页码: 13
作者:
Sun, Zhongya
;
Zhang, Hao
;
Zhang, Yuanyuan
;
Liao, Liping
;
Zhou, Wen
  |  
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2020/07/01
anti-metastasis activities
crystal structures
inhibitors
novel pockets
rho family proteins
A Novel G Protein-Biased and Subtype-Selective Agonist for a G Protein-Coupled Receptor Discovered from Screening Herbal Extracts
期刊论文
OAI收割
ACS CENTRAL SCIENCE, 2020, 卷号: 6, 期号: 2, 页码: 213-225
作者:
Zhang, Bingjie
;
Zhao, Simeng
;
Yang, Dehua
;
Wu, Yiran
;
Xin, Ye
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
Antihypertensive Effects of Two Novel Angiotensin I-Converting Enzyme (ACE) Inhibitory Peptides from Gracilariopsis lemaneiformis (Rhodophyta) in Spontaneously Hypertensive Rats (SHRs)
期刊论文
OAI收割
MARINE DRUGS, 2018, 卷号: 16, 期号: 9, 页码: 16
作者:
Deng, Zhenzhen
;
Liu, Yingjuan
;
Wang, Jing
;
Wu, Suhuang
;
Geng, Lihua
  |  
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2019/08/27
Gracilariopsis lemaneiformis
ACE-inhibitory activity
peptide
molecular docking
SHRs
Structure alignment-based classification of RNA-binding pockets reveals regional RNA recognition motifs on protein surfaces
期刊论文
OAI收割
BMC BIOINFORMATICS, 2017, 卷号: 18, 页码: 13
作者:
Liu, Zhi-Ping
;
Liu, Shutang
;
Chen, Ruitang
;
Huang, Xiaopeng
;
Wu, Ling-Yun
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2018/07/30
RNA-binding pocket
Local structure classification
Structural alignment
Network clustering
Structure motif
A unifying phase diagram with correlation-driven superconductor-to-insulator transition for the 122*series of iron chalcogenides
期刊论文
OAI收割
PHYSICAL REVIEW B, 2016, 卷号: 93, 期号: 5, 页码: 1-8
作者:
Niu, X. H.
;
Chen, S. D.
;
Jiang, J.
;
Ye, Z. R.
;
Yu, T. L.
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2017/10/30