中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共11条,第1-10条 帮助

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Different conformational responses of the beta(2)-adrenergic receptor-Gs complex upon binding of the partial agonist salbutamol or the full agonist isoprenaline 期刊论文  OAI收割
NATIONAL SCIENCE REVIEW, 2021, 卷号: 8
作者:  
Yang, Fan;  Ling, Shenglong;  Zhou, Yingxin;  Zhang, Yanan;  Lv, Pei
  |  收藏  |  浏览/下载:31/0  |  提交时间:2021/11/01
Insights into the molecular mechanism of positive cooperativity between partial agonist MK-8666 and full allosteric agonist AP8 of hGPR40 by Gaussian accelerated molecular dynamics (GaMD) simulations 期刊论文  OAI收割
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2021, 卷号: 19, 页码: 3978-3989
作者:  
An, Xiaoli;  Bai, Qifeng;  Bing, Zhitong;  Liu, Huanxiang;  Yao, Xiaojun
  |  收藏  |  浏览/下载:17/0  |  提交时间:2021/12/08
Discovery of Potent and Orally Bioavailable GPR40 Full Agonists Bearing Thiophen-2-ylpropanoic Acid Scaffold 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 7, 页码: 2697-2717
作者:  
Li, He;  Huang, Qi;  Chen, Cheng;  Xu, Bin;  Wang, He-Yao
  |  收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D-1, D-2 and serotonin 5-HT1A multi-action profile 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 4, 页码: 856-868
作者:  
Sun, Haifeng;  Zhu, Liyuan;  Yang, Huicui;  Qian, Wangke;  Guo, Lin
  |  收藏  |  浏览/下载:22/0  |  提交时间:2019/01/08
Synthesis of Dihydrofuroaporphine Derivatives: Identification of a Potent and Selective Serotonin 5-HT1A Receptor Agonist 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2010, 卷号: 53, 期号: 3, 页码: 1319-1328
作者:  
Liu, Zhili;  Zhang, Hai;  Ye, Na;  Zhang, Jing;  Wu, QianQian
  |  收藏  |  浏览/下载:13/0  |  提交时间:2019/01/08
Pharmacological Characterization of ATPM [(-)-3-Amino-thiazolo[5,4-b]-N-cyclopropylmethylmorphinan hydrochloride], a Novel Mixed kappa-Agonist and mu-Agonist/-Antagonist That Attenuates Morphine Antinociceptive Tolerance and Heroin Self-Administration Behavior 期刊论文  OAI收割
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2009, 卷号: 329, 期号: 1, 页码: 306-313
作者:  
Wang, Yu-Jun;  Tao, Yi-Min;  Li, Fu-Ying;  Wang, Yu-Hua;  Xu, Xue-Jun
  |  收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08
Effects of adrenergic agonists on the extrahepatic expression of vitellogenin Ao1 in heart and brain of the Chinese rare minnow (Gobiocypris rarus) 期刊论文  OAI收割
AQUATIC TOXICOLOGY, 2009, 卷号: 91, 期号: 1, 页码: 19-25
作者:  
Ma, Liwen;  Li, Dongliang;  Wang, Jianwei;  He, Jiangyan;  Yin, Zhan
收藏  |  浏览/下载:106/9  |  提交时间:2010/10/13
Pyrazolidine-3,5-dione derivatives as potent non-steroidal agonists of farnesoid X receptor: Virtual screening, synthesis, and biological evaluation 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 卷号: 18, 期号: 20, 页码: 5497-5502
作者:  
Deng, Guanghui;  Li, Weihua;  Shen, Jianhua;  Jiang, Hualiang;  Chen, Kaixian
  |  收藏  |  浏览/下载:13/0  |  提交时间:2019/01/08
Recent advances towards the discovery of dopamine receptor ligands 期刊论文  OAI收割
EXPERT OPINION ON THERAPEUTIC PATENTS, 2006, 卷号: 16, 期号: 5, 页码: 587-630
作者:  
Zhang, Ao;  Kan, Ying;  Li, Fuying
  |  收藏  |  浏览/下载:21/0  |  提交时间:2019/01/08
Dose-dependent effects of the dopamine D1 receptor agonists A77636 or SKF81297 on spatial working memory in aged monkeys 期刊论文  OAI收割
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 1997, 卷号: 283, 期号: 1, 页码: 183-189
作者:  
Cai JX;  Arnsten AFT
收藏  |  浏览/下载:9/0  |  提交时间:2010/08/24