中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [18]
大连化学物理研究所 [6]
昆明植物研究所 [1]
武汉植物园 [1]
上海生物化学与细胞生... [1]
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OAI收割 [26]
iSwitch采集 [1]
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期刊论文 [25]
会议论文 [2]
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2024 [1]
2023 [3]
2021 [1]
2020 [1]
2019 [1]
2018 [3]
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物理化学 [3]
Neuroscien... [1]
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A proteomic landscape of pharmacologic perturbations for functional relevance
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2024, 卷号: 14, 期号: 1, 页码: 128-139
作者:
Liu, Zhiwei
;
Jiang, Shangwen
;
Hao, Bingbing
;
Xie, Shuyu
;
Liu, Yingluo
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/04/09
Proteomics
Drug
Perturbation
Drug target
Drug combination
Qing-Zhi-Tiao-Gan-Tang (QZTGT) prevents nonalcoholic steatohepatitis (NASH) by expression pattern correction
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 317, 页码: 14
作者:
Chu, Hang
;
Zhang, Weitao
;
Tan, Yan
;
Diao, Zhipeng
;
Li, Peng
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
Fibrosis
Inflammation
Lipogenesis
NASH
QZTGT
TMNP
Design, Synthesis, and Pharmacological Evaluation of Isoindoline Analogues as New HPK1 Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 23, 页码: 16201-16221
作者:
Xie, Chenghu
;
Liu, Bo
;
Song, Zilan
;
Yang, Ye
;
Dai, Mengdi
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/02/27
Oral pectin/oligochitosan microspheres for colon-specific controlled release of quercetin to treat inflammatory bowel disease
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2023, 卷号: 316, 页码: 15
作者:
Jing, Shisuo
;
Chen, Huayuan
;
Liu, Ergang
;
Zhang, Meng
;
Shen, Huan
  |  
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2023/10/17
Inflammatory bowel disease
Quercetin
colon-targeted delivery
Pectin microsphere
Oligochitosan
Immune microenvironment
Label-free cell phenotypic study of opioid receptors and discovery of novel mu opioid ligands from natural products
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 270, 页码: 113872
作者:
Hou,Tao
;
Xu,Fangfang
;
Peng,Xingrong
;
Zhou,Han
;
Zhang,Xiuli
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2022/04/02
Opioid receptors
Dynamic mass redistribution
Natural products
Antagonist
Selectivity
IDENTIFICATION
ANTAGONISTS
SUBSTANCES
NALOXEGOL
AGONISTS
SAFETY
MACA
Synthesis and biological investigation of triazolopyridinone derivatives as potential multireceptor atypical antipsychotics
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 8, 页码: 6
作者:
Shi, Wenqiang
;
Wang, Yu
;
Wu, Chunhui
;
Yang, Feipu
;
Zheng, Wei
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
Triazolopyridinone
Antipsychotic
Multireceptor
5-HT1A receptor
Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5579-5593
作者:
Zhang, Xianglei
;
Dong, Guangyu
;
Li, Heng
;
Chen, Wuyan
;
Li, Jian
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Positive Allosteric Modulation of AMPAR by PF-4778574 Produced Rapid Onset Antidepressant Actions in Mice
期刊论文
OAI收割
Cerebral cortex (New York, N.Y. : 1991), 2018
作者:
Shen, Mengxin
;
Lv, Dan
;
Li, Shuting
;
Zhang, Yanhua
;
Wang, Zhen
  |  
收藏
  |  
浏览/下载:104/0
  |  
提交时间:2019/01/08
Discovery of novel antagonists on (2)-adrenoceptor from natural products using a label-free cell phenotypic assay
期刊论文
OAI收割
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2018, 卷号: 391, 期号: 12, 页码: 1411-1420
作者:
Wang, Anhui
;
Zhang, Pengyu
;
Wang, Jixia
;
Zhao, Ying
;
Zhang, Xiuli
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2019/06/20
beta(2)-Adrenoceptor
Antagonist
Natural product
Label-free cell phenotypic assay
Discovery of novel antagonists on (2)-adrenoceptor from natural products using a label-free cell phenotypic assay
期刊论文
iSwitch采集
Naunyn-schmiedebergs archives of pharmacology, 2018, 卷号: 391, 期号: 12, 页码: 1411-1420
作者:
Zhang, Pengyu
;
Wang, Jixia
;
Zhao, Ying
;
Zhang, Xiuli
;
Qu, Lala
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2019/05/08
Beta(2)-adrenoceptor
Antagonist
Natural product
Label-free cell phenotypic assay