中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
沈阳自动化研究所 [60]
上海光学精密机械研究... [9]
上海药物研究所 [6]
地理科学与资源研究所 [2]
长春光学精密机械与物... [1]
数学与系统科学研究院 [1]
更多
采集方式
OAI收割 [80]
内容类型
专利 [29]
期刊论文 [26]
会议论文 [24]
学位论文 [1]
发表日期
2024 [1]
2023 [1]
2022 [3]
2021 [4]
2020 [5]
2019 [6]
更多
学科主题
筛选
浏览/检索结果:
共80条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
Discovery of pyrrolo[2,3-d]pyrimidin-4-one derivative YCH3124 as a potent USP7 inhibitor for cancer therapy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 277, 页码: 17
作者:
Zhuang, Zhen
;
Miao, Yu-Ling
;
Song, Shan-Shan
;
Leng, Guang-Tong
;
Zhang, Xiao-Fei
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/09/26
USP7 inhibitor
Structure-activity relationships
Anti-cancer
pyrrolo[2,3-d]pyrimidin-4-one
Phenotypic screening-based drug discovery of furan-2-carboxylic acid derivatives for the amelioration of type 2 diabetes mellitus (T2DM)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 246, 页码: 11
作者:
Chen, Lili
;
Huang, Suling
;
Ye, Yangliang
;
Shen, Yu
;
Xu, Tifei
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2023/04/10
Phenotypic screening
Gluconeogenesis
Furan-2-carboxylic acid
T2DM
Design and exploration of gut-restricted bifunctional molecule with TGR5 agonistic and DPP4 inhibitory effects for treating ulcerative colitis
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 242, 页码: 114697
作者:
Han, Fanghui
;
Ning, Mengmeng
;
Wang, Kai
;
Gu, Yipei
;
Qu, Hui
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/03/21
Bifunctional molecule
Gut-restricted
Ulcerative colitis
TGR5
DPP4
The Important Role of Global State for Multi-Agent Reinforcement Learning
期刊论文
OAI收割
Future Internet, 2022, 卷号: 14, 期号: 1, 页码: 1-9
作者:
Li SL(李帅龙)
;
Zhang W(张伟)
;
Leng YQ(冷雨泉)
;
Wang XH(王晓辉)
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/01/27
multi-agent reinforcement learning
environmental information
deep reinforcement learning
Proximal policy optimization with model-based methods
期刊论文
OAI收割
JOURNAL OF INTELLIGENT & FUZZY SYSTEMS, 2022, 卷号: 42, 期号: 6, 页码: 5399-5410
作者:
Li SL(李帅龙)
;
Zhang W(张伟)
;
Zhang HW(张会文)
;
Zhang X(张鑫)
;
LLeng YQ(冷雨泉)
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/05/29
Model-based reinforcement learning
model-free reinforcement learning
policy optimization method
Discovery of novel ketoxime ether derivatives with potent FXR agonistic activity, oral effectiveness and high liver/blood ratio
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 43, 页码: 13
作者:
Tang, Xuehang
;
Ning, Mengmeng
;
Ye, Yangliang
;
Gu, Yipei
;
Yan, Hongyi
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2021/11/04
FXR agonist
Ketoxime ether
Target genes
Liver
blood ratio
Systemic activation
Foot placement prediction for assistive walking by fusing sequential 3D gaze and environmental context
期刊论文
OAI收割
IEEE Robotics and Automation Letters, 2021, 卷号: 6, 期号: 2, 页码: 2509-2516
作者:
Zhang, Kuangen
;
Liu, Haiyuan
;
Fan, Zixuan
;
Chen, Xinxing
;
Leng YQ(冷雨泉)
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/03/21
3D gaze
foot placement prediction
intention recognition
prosthetics and exoskeletons
sensor/data fusion
A Model-Based Exploration Policy in Deep Q-Network
会议论文
OAI收割
Virtual, Chengdu, China, December 3-4, 2021
作者:
Li SL(李帅龙)
;
Zhang W(张伟)
;
Leng YQ(冷雨泉)
;
Zhang X(张鑫)
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/03/07
reinforcement learning
exploration and exploitation dilemma
model-based exploration method
A plane extraction approach in inverse depth images based on region-growing
期刊论文
OAI收割
Sensors (Switzerland), 2021, 卷号: 21, 期号: 4, 页码: 1-15
作者:
Han XN(韩小宁)
;
Wang XH(王晓辉)
;
Leng YQ(冷雨泉)
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/02/27
plane extraction
region growing
RGBD camera
normal estimation
Fabrication of hybrid graphene/CdS quantum dots film with the flexible photo-detecting performance
期刊论文
OAI收割
PHYSICA E-LOW-DIMENSIONAL SYSTEMS & NANOSTRUCTURES, 2020, 卷号: 124, 页码: 6
作者:
Chan, Yang
;
Dahua, Zhou
;
Jun, Yang
;
Lilong, Tan
;
Chongqian, Leng
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/12/01
Graphene
CdS Quantum dots
Hybrid film
Flexible photodetector