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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
化学研究所 [6]
长春应用化学研究所 [5]
大连化学物理研究所 [4]
过程工程研究所 [3]
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期刊论文 [34]
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2023 [3]
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Formaldehy... [1]
材料科学与物理化学 [1]
波谱分析 [1]
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Physiological and Pathological Functions of TRPM7 Channel and Its Small-molecule Modulators
期刊论文
OAI收割
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2023, 卷号: 50, 期号: 12, 页码: 2856-2868
作者:
Wang, Yun-Qi
;
Guan, Zi-Yue
;
Gao, Zhao-Bing
;
Zheng, Yue-Ming
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/04/09
TRPM7
ion channel
physiological function
disease
small molecule modulators
C-terminal modification and functionalization of proteins via a self-cleavage tag triggered by a small molecule
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 13
作者:
Zeng, Yue
;
Shi, Wei
;
Liu, Zhi
;
Xu, Hao
;
Liu, Liya
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/02/19
Discovery of a Novel Bifunctional Steroid Analog, YXG-158, as an Androgen Receptor Degrader and CYP17A1 Inhibitor for the Treatment of Enzalutamide-Resistant Prostate Cancer
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 14, 页码: 9972-9991
作者:
Wang, Ao
;
Luo, Xianggang
;
Meng, Xin
;
Lu, Zhengyu
;
Chen, Kaixian
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
Design and exploration of gut-restricted bifunctional molecule with TGR5 agonistic and DPP4 inhibitory effects for treating ulcerative colitis
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 242, 页码: 114697
作者:
Han, Fanghui
;
Ning, Mengmeng
;
Wang, Kai
;
Gu, Yipei
;
Qu, Hui
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/21
Bifunctional molecule
Gut-restricted
Ulcerative colitis
TGR5
DPP4
DNA-encoded focused indazole library synthesis by a palladium- mediated C-N(sp(2)) cross-coupling reaction between DNA-linked (hetero)aryl halides and aromatic nitrogen heterocycles
期刊论文
OAI收割
TETRAHEDRON LETTERS, 2022, 卷号: 96, 页码: 6
作者:
Yang, Juan
;
Xia, Shengdi
;
Liu, Jiaxiang
;
Yu, Zikun
;
Mei, Lianghe
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/08/16
Mechanistic Insight into Methacrolein Formation from Formaldehyde and Propionaldehyde
期刊论文
OAI收割
Catalysis Letters, 2022, 卷号: 152, 期号: 3, 页码: 799-805
作者:
Yan, Ruiyi
;
Lv, Zhaopo
;
Tang, Hongguo
;
Bai, Yinge
;
Li, Mengyue
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2023/06/26
Reaction intermediates - Ketones - Condensation - Condensation reactions
Helicobacter pylori FabX contains a [4Fe-4S] cluster essential for unsaturated fatty acid synthesis
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2021, 卷号: 12
作者:
Zhou, Jiashen
;
Zhang, Lin
;
Zeng, Liping
;
Yu, Lu
;
Duan, Yuanyuan
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2022/01/10
Bifunctional electrochemical detection of organic molecule and heavy metal at two-dimensional Sn-In2S3 nanocomposite
期刊论文
OAI收割
MICROCHEMICAL JOURNAL, 2020, 卷号: 159, 页码: 9
作者:
Fu, Yanqiu
;
Zhang, Yang
;
Zheng, Shili
;
Jin, Wei
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/03/29
Sn-doping In2S3 nanosheets
Dual-function
UA
Pb(II)
Electrochemical detection
Facile synthesis of chiral epsilon-sultams via an organocatalytic aza-Friedel-Crafts reaction
期刊论文
OAI收割
ORGANIC & BIOMOLECULAR CHEMISTRY, 2019, 卷号: 17, 期号: 26, 页码: 6364-6368
作者:
Zhao, Zi-Biao
;
Shi, Lei
;
Li, Yaming
;
Meng, Fan-Jie
;
Zhou, Yong-Gui
  |  
收藏
  |  
浏览/下载:96/0
  |  
提交时间:2019/12/02
Synthesis and In Vitro Antitumor Activity of Novel Bivalent -Carboline-3-carboxylic Acid Derivatives with DNA as a Potential Target
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 10
作者:
Gu, Hongling
;
Li, Na
;
Dai, Jiangkun
;
Xi, Yaxi
;
Wang, Shijun
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
bivalent -carbolines
antitumor
apoptosis
DNA-binding affinity
bcl-2