机构

• 上海药物研究所 [16]
• 过程工程研究所 [1]
• 长春应用化学研究所 [1]
• 上海硅酸盐研究所 [1]

采集方式

• OAI收割 [19]

内容类型

• 期刊论文 [19]

发表日期

• 2024 [6]
• 2023 [2]
• 2022 [3]
• 2021 [3]
• 2019 [1]
• 2017 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共19条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 F-CPI: A Multimodal Deep Learning Approach for Predicting Compound Bioactivity Changes Induced by Fluorine Substitution 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 13 作者:     |  收藏  |  浏览/下载：12/0  |  提交时间：2025/02/28 Design, synthesis, and evaluation of novel oxyacanthine derivatives for anti-SARS-CoV-2 activity 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 113, 页码: 5 作者:  Lu, Jie;  Cheng, Yan;  Zhang, Yumin;  Wang, Yi;  Xia, Bingqing   |  收藏  |  浏览/下载：9/0  |  提交时间：2025/02/28 Bisbenzylisoquinoline alkaloid  Oxyacanthine derivatives  SARS-CoV-2   Discovery of the potent covalent inhibitor with an acrylate warhead for SARS-CoV-2 3CL protease 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 112, 页码: 5 作者:  Shen, Wen;  Chen, Xinyao;  Zhou, Liping;  Cheng, Yan;  Zhang, Yan   |  收藏  |  浏览/下载：25/0  |  提交时间：2024/10/21 COVID-19  SARS-CoV-2 3CL pro inhibitor  Drug design  Antiviral activities   Design, synthesis, and biological evaluation of novel 1-amido-2-one-4-thio-deoxypyranose as potential antitumor agents for multiple myeloma 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 111, 页码: 16 作者:  Li, Xiaomei;  Zhang, Hui;  Dong, Sanfeng;  Gao, Xuejie;  Sun, Haiguo   |  收藏  |  浏览/下载：29/0  |  提交时间：2024/09/26 Multiple myeloma  1-amido-2-one-4-thio-deoxypyranose  TRIP13 inhibitor  In vivo activity   Identification of Dihydrobenzofuran Neolignans as Novel PDE4 Inhibitors and Evaluation of Antiatopic Dermatitis Efficacy in DNCB-Induced Mice Model 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4855-4869 作者:  Gu, Chenming;  Liu, Jiayuan;  Qian, Fei;  Yu, Wenchao;  Huang, Doudou   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/05/07 Cannabidiol exhibits anxiolytic-like effects and antipsychotic-like effects in mice models 期刊论文  OAI收割 NEUROSCIENCE LETTERS, 2024, 卷号: 826, 页码: 8 作者:  Shu, Guangzhao;  He, Yang;  Suo, Jin;  Wu, Chunhui;  Gong, Xudong   |  收藏  |  浏览/下载：29/0  |  提交时间：2024/06/27 Cannabidiol  Stress-induced hyperthermia  Phencyclidine-induced negative symptoms of  schizophrenia model  5-HT 1A receptor   Design, synthesis and biological evaluation of peptidomimetic benzothiazolyl ketones as 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 13 作者:  Yang, Hanxi;  You, Mengyuan;  Shu, Xiaoyang;  Zhen, Jingyao;  Zhu, Mengwei   |  收藏  |  浏览/下载：30/0  |  提交时间：2023/10/17 Peptidomimetics  Benzothiazolyl ketone  3CLpro inhibitor  Pharmacokinetic properties  SARS-CoV-2   Synthesis, cytotoxicity, and pharmacokinetic evaluations of niclosamide analogs for anti-SARS-CoV-2 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 253, 页码: 11 作者:  Li, Rui;  Zhang, Zherui;  Huang, Shuhong;  Peng, Ke;  Jiang, Hualiang   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/10/17 SARS-CoV-2  Niclosamide analogs  Cytotoxicity  Pharmacokinetic  SKP2 inhibition   Molecular recognition of morphine and fentanyl by the human mu-opioid receptor 期刊论文  OAI收割 CELL, 2022, 卷号: 185, 期号: 23, 页码: 4361-+ 作者:  Zhuang, Youwen;  Wang, Yue;  He, Bingqing   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/04/10 Synthesis and biological evaluation of artemisinin derivatives as potential MS agents 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022, 卷号: 64, 页码: 5 作者:  Zhang, Yan;  Lv, Jie;  Zhang, Suqing;  Yang, Hanxi;  Shen, Jingshan   |  收藏  |  浏览/下载：39/0  |  提交时间：2022/08/16 Artemisinin derivatives  Multiple sclerosis  Th1/Th17  IFN-?/IL-17A  EAE