中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [110]
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期刊论文 [527]
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De Novo Design of Structure-Tunable Multivalent Targeting Chimeras for Tumor-Targeted PD-L1 Degradation and Potentiated Cancer Immunotherapy
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 17
作者:
Zhou, Huiling
;
Hou, Bo
;
Shan, Yiming
;
Huang, Lujia
;
Chen, Fangmin
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/06/23
Combinatory therapy, Immune checkpoint blockade, Multivalent targeting chimeras
Tumor microenvironment
Tumor-specific PD-L1 degradation
Tailoring nanovectors for optimal neoantigen vaccine efficacy
期刊论文
OAI收割
JOURNAL OF MATERIALS CHEMISTRY B, 2025, 卷号: 13, 期号: 13, 页码: 4045-4058
作者:
Zheng, Youshi
;
Wang, Bing
;
Cai, Zhixiong
;
Lai, Zisen
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/04/24
Self-Oxygenating PROTAC Microneedle for Spatiotemporally-Confined Protein Degradation and Enhanced Glioblastoma Therapy
期刊论文
OAI收割
ADVANCED MATERIALS, 2025, 页码: 13
作者:
Jiang, Xingyu
;
Lai, Yi
;
Xia, Wenzheng
;
Yang, Wenfang
;
Wang, Junjue
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/04/24
acid-activatable photodynamic therapy
double-layered microneedle
glioblastoma therapy
light-activatable PROTAC prodrug
protein degradation
Saline-CO
2
Solution Effects on the Mechanical Properties of Sandstones: An Experimental Study
期刊论文
OAI收割
APPLIED SCIENCES-BASEL, 2025, 卷号: 15, 期号: 2, 页码: 19
作者:
Duan, Motao
;
Mao, Haijun
;
Zhang, Guangquan
;
Liu, Junxin
;
Zhu, Sinan
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/06/27
sandstone
CO2 solution
salinity formula
nuclear magnetic resonance (NMR)
pore
EGCG-enabled Deep Tumor Penetration of Phosphatase and Acidity Dual-responsive Nanotherapeutics for Combinatory Therapy of Breast Cancer
期刊论文
OAI收割
SMALL, 2024, 页码: 20
作者:
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/12/16
chemo/chemodynamic therapy
EGCG
nanomedicine
TGF-beta signaling
triple-negative breast cancer
Dynamic polyphenol nanoparticles boost cuproptosis-driven metalloimmunotherapy of breast cancer
期刊论文
OAI收割
NANO TODAY, 2024, 卷号: 58, 页码: 12
作者:
Zhang, Huijuan
;
Chen, Fangmin
;
Cheng, Wenhao
;
Lai, Yi
;
Hou, Bo
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/10/09
Polyphenol
Cuproptosis
Dynamic covalent bond
Cancer metalloimmunotherapy
Tumor immune microenvironment
Modulation of fatty acid profiles and turnover dynamics in jellyfish polyps through copepod diets: Insights into trophic interactions and nutrient flux
期刊论文
OAI收割
ECOLOGY AND EVOLUTION, 2024, 卷号: 14, 期号: 10, 页码: 11
作者:
Chi, Xupeng
;
Zhang, Fang
;
Sun, Song
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/12/20
bioconversion
copepod
fatty acid
food quality
jellyfish
turnover
Targeting the Labile Iron Pool with Engineered DFO Nanosheets to Inhibit Ferroptosis for Parkinson's Disease Therapy
期刊论文
OAI收割
ADVANCED MATERIALS, 2024, 页码: 23
作者:
Lei, Li
;
Yuan, Jiali
;
Dai, Zhijun
;
Xiang, Song
;
Tu, Qiuxia
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/10/21
antioxidant system
engineered nanoregulator
ferroptosis
labile iron pool
Parkinson's disease
Effects of marine eutrophication environment on microbial corrosion: A review
期刊论文
OAI收割
MARINE POLLUTION BULLETIN, 2024, 卷号: 205, 页码: 17
作者:
Guo, Ding
;
Wang, Yanan
;
Zhang, Yimeng
;
Duan, Jizhou
;
Guan, Fang
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/09/02
Marine environment
Eutrophication
Microbiologically influenced corrosion
Nutrients
Estuary
In-situ vaccination immunotherapy of colorectal cancer with STING agonist-integrated supramolecular nanovectors
期刊论文
OAI收割
NANO TODAY, 2024, 卷号: 56, 页码: 13
作者:
Liu, Xiaoying
;
Chen, Fangmin
;
Saeed, Madiha
;
Li, Xutong
;
Zhang, Huijuan
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/07/12
Supramolecular nanovector
STING activation
Colorectal cancer
In -situ vaccination
Cancer immunotherapy