中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
大连化学物理研究... [209]
上海药物研究所 [12]
地理科学与资源研究所 [1]
国家天文台 [1]
青岛生物能源与过程研... [1]
采集方式
OAI收割 [222]
iSwitch采集 [2]
内容类型
期刊论文 [125]
会议论文 [61]
专利 [37]
标准 [1]
发表日期
2024 [1]
2023 [6]
2022 [2]
2021 [1]
2020 [1]
2019 [6]
更多
学科主题
物理化学 [83]
药物化学 [15]
张晨 [11]
生物药物学 [7]
化学其他学科 [4]
药学其他学科 [4]
更多
筛选
浏览/检索结果:
共224条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
Design, synthesis and structure-activity relationship of 1,8-naphthalimide derivatives as highly potent hCYP1B1 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 107, 页码: 8
作者:
Wei, Yueyue
;
Xiong, Yuan
;
Liao, Qingyi
;
Yang, Ya
;
Tian, Tian
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/07/12
8-naphthalimide
Structure -activity relationships (SAR)
Paclitaxel (PTX) resistance
Molecular docking
Design, synthesis and biological evaluation of chalcone derivatives as potent and orally active hCYP3A4 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 9
作者:
Lu, Shiwei
;
Zhang, Feng
;
Gong, Jiahao
;
Huang, Jian
;
Zhu, Guanghao
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/12/08
Cytochrome P450 3A4 (CYP3A4)
Inhibitors
Isoquinoline chalcones
Orally active
Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 91, 页码: 11
作者:
Zhao, Yitian
;
Zhang, Min
;
Hou, Xudong
;
Han, Jiaxin
;
Qin, Xiaoya
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/10/17
Salicylanilide
hPL inhibitor
Structure -activity relationship
Anti -obesity
Discovery of seven-membered ring berberine analogues as highly potent and specific hCES2A inhibitors
期刊论文
OAI收割
CHEMICO-BIOLOGICAL INTERACTIONS, 2023, 卷号: 378, 页码: 11
作者:
Yang, Yun
;
Xiong, Yuan
;
Zhu, Guanghao
;
Sun, Mengru
;
Zou, Kun
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2023/10/17
Human carboxylesterase 2 (hCES2A)
Berberine analogues
Structure -activity relationships (SAR)
Inhibition kinetics
Selectivity
Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2
期刊论文
OAI收割
Signal Transduction and Targeted Therapy, 2023, 卷号: 8, 期号: 5, 页码: 2384-2391
作者:
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2024/03/27
Ginkgolic acids inhibit SARS-CoV-2 and its variants by blocking the spike protein/ACE2 interplay
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 卷号: 226, 页码: 780-792
作者:
Xiang, Yusen
;
Zhai, Guanglei
;
Li, Yaozong
;
Wang, Mengge
;
Chen, Xixiang
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/04/10
SARS-CoV-2
S-RBD
Ginkgolic acid
Discovery and mechanism of action of Thonzonium bromide from an FDA-approved drug library with potent and broad-spectrum inhibitory activity against main proteases of human coronaviruses
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 11
作者:
Wang, Ruyu
;
Zhai, Guanglei
;
Zhu, Guanghao
;
Wang, Mengge
;
Gong, Xiaoyi
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/04/10
SARS-CoV-23CLpro
Thonzonium bromide
Mechanism of action
Broad-spectrum inhibitor
Chemo- and Site-Selective Lysine Modification of Peptides and Proteins under Native Conditions Using the Water-Soluble Zolinium
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 14
作者:
Sun, Haiguo
;
Xi, Mengyu
;
Jin, Qiang
;
Zhu, Zhengdan
;
Zhang, Yani
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2022/09/30
Stable, Bright, and Long-Fluorescence-Lifetime Dyes for Deep-Near- Infrared Bioimaging
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2022, 页码: 12
作者:
Li, Jin
;
Dong, Yan
;
Wei, Ruwei
;
Jiang, Guanyu
;
Yao, Cheng
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2022/08/30
Structure-Based Virtual Screening and Identification of Potential Inhibitors of SARS-CoV-2 S-RBD and ACE2 Interaction
期刊论文
OAI收割
FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 12
作者:
Xiong, Jiacheng
;
Xiang, Yusen
;
Huang, Ziming
;
Liu, Xiaohong
;
Wang, Mengge
  |  
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2021/12/01
SARS-CoV-2
angiotensin-converting enzyme 2 (ACE2)
spike protein receptor-binding domain (S-RBD)
structure-based virtual screening
protein-protein interaction (PPI) inhibitors