中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [23]
力学研究所 [19]
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期刊论文 [102]
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Discovery of indole derivatives as STING degraders
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 21
作者:
An, Yuxiang
;
Zhang, Yan
;
Luo, Xin
;
Lan, Yaohan
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Autoimmune diseases
Degrader
Inflammatory
PROTAC
STING
Research progress on critical viral protease inhibitors for coronaviruses and enteroviruses
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 122, 页码: 19
作者:
Hu, Shulei
;
Zhong, Qiuyu
;
Xie, Xiong
;
Zhang, Shurui
;
Wang, Jinlin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/05/27
Innate immunity response
SARS-CoV-2 3CLpro
PLpro
EV71 3Cpro
2Apro
Viral protease inhibitor
Diterpenoids and diarylheptanoids from the fruits of
Alpinia
zerumbet
and their anti-inflammatory activity
期刊论文
OAI收割
FITOTERAPIA, 2025, 卷号: 184, 页码: 10
作者:
Zhang, Zhenghan
;
Li, Guangqian
;
Luo, Xin
;
Xiao, Fang
;
Zhang, Yan
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Alpinia zerumbet
Labdane-type diterpenoid
Diarylheptanoid
Anti-inflammatory
ISG pathway
TDDFT ECD calculation
Discovery of a non-nucleotide stimulator of interferon genes (STING) agonist with systemic antitumor effect
期刊论文
OAI收割
MEDCOMM, 2025, 卷号: 6, 期号: 1, 页码: e70001
作者:
Wang, Xiyuan
;
Zhan, Zhengsheng
;
Wang, Zhen
;
Zhang, Yan
;
Zhao, Kaiyan
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/06/04
antitumor
immune memory
innate immunity
STING agonist
Biofluid-Derived Exosomal LncRNAs: Their Potential in Obesity and Related Comorbidities
期刊论文
OAI收割
BIOLOGY-BASEL, 2024, 卷号: 13, 期号: 12, 页码: 18
作者:
Ngowi, Ebenezeri Erasto
;
Lu, Tuyan
;
Liu, Qing
;
Xie, Xianghong
;
Wang, Ning
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/02/28
biofluids
exosomes
long non-coding RNAs
obesity and associated diseases
Ruthenium(II)-Catalyzed Pyridyl-Directed Tryptophan C-H Acylmethylation with
α
-Chloro Ketones
期刊论文
OAI收割
ADVANCED SYNTHESIS & CATALYSIS, 2024, 页码: 7
作者:
Hu, Shulei
;
Wang, Yong
;
Xie, Xiong
;
Liang, Renwen
;
Liu, Hong
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/12/16
C-H functionalization
Ru(II)-catalyzed
Acylmethylation
alpha
-chloro ketones
Tryptophan-containing peptide
Enhanced Effects of Intermittent Fasting by Magnetic Fields in Severe Diabetes
期刊论文
OAI收割
RESEARCH, 2024, 卷号: 7
作者:
Wang, Ying
;
Feng, Chuanlin
;
Yu, Biao
;
Wang, Junjun
;
Chen, Weili
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/11/20
Heterozygous variants in USP25 cause genetic generalized epilepsy
期刊论文
OAI收割
BRAIN, 2024, 页码: 16
作者:
Fan, Cui-Xia
;
Liu, Xiao-Rong
;
Mei, Dao-Qi
;
Li, Bing-Mei
;
Li, Wen-Bin
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2024/10/09
genetic generalized epilepsy
USP25
gain of function
loss of function
Rotating magnetic field inhibits Aβ protein aggregation and alleviates cognitive impairment in Alzheimer's disease mice
期刊论文
OAI收割
ZOOLOGICAL RESEARCH, 2024, 卷号: 45
作者:
Guo, Ruo-Wen
;
Xie, Wen-Jing
;
Yu, Biao
;
Song, Chao
;
Ji, Xin-Miao
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/11/22
Alzheimer's disease
Rotating magnetic field
Amyloid-beta
Cognitive function
Alzheimer's disease animal models
A novel approach to exploit Small-Molecule glucagon-like Peptide-1 receptor agonists with high potency
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 107, 页码: 19
作者:
Wang, Xiaoyan
;
Yun, Ying
;
Chen, Lili
;
Guo, Shimeng
;
Niu, Buying
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2024/07/12
Diabetes
GLP-1 receptor
Agonist
Structural optimization
Water molecule replacement
Structure activity relationship
Docking simulation