中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [28]
地理科学与资源研究... [13]
自动化研究所 [1]
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OAI收割 [42]
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期刊论文 [38]
专利 [3]
学位论文 [1]
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2024 [13]
2023 [15]
2022 [11]
2021 [2]
2020 [1]
学科主题
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Harnessing acylhydrazone-oxime exchange reaction to achieve diverse synthesis of glycosite-specific antibody-drug conjugates
期刊论文
OAI收割
ORGANIC & BIOMOLECULAR CHEMISTRY, 2024, 页码: 9
作者:
Xia, Fei
;
Liu, Zhi
;
Hang, Jiaying
;
Xu, Hao
;
Xiao, Yuting
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/04/01
SurfDock is a surface-informed diffusion generative model for reliable and accurate protein-ligand complex prediction
期刊论文
OAI收割
NATURE METHODS, 2024, 页码: 24
作者:
Cao, Duanhua
;
Chen, Mingan
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/01/06
Protein-encapsulated long-wavelength fluorescent probe hybrid for imaging lipid droplets in living cells and mice with non-alcoholic fatty liver
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2024, 卷号: 35, 期号: 11, 页码: 6
作者:
Wang, Han-Min
;
Li, Yan-Chen
;
Sun, Lu-Lu
;
Tang, Ming-Ye
;
Liu, Jia
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/09/26
Lipid droplets imaging
Fluorescent probe
Large Stokes shift
Protein encapsulation
Non-alcoholic fatty liver
Tofacitinib prevents depressive-like behaviors through decreased hippocampal microgliosis and increased BDNF levels in both LPS-induced and CSDS-induced mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 13
作者:
Gao, Ya-nan
;
Pan, Kai-jun
;
Zhang, Yong-mei
;
Qi, Ying-bei
;
Chen, Wen-gang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/11/05
tofacitinib
depression
JAK-STAT pathway
microgliosis
synaptic defects
Development of a First-in-Class DNMT1/HDAC Inhibitor with Improved Therapeutic Potential and Potentiated Antitumor Immunity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 18, 页码: 16480-16504
作者:
Chang, Yingjie
;
Guo, Huahui
;
Li, Xue
;
Zong, Liangyi
;
Wei, Jiale
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/10/21
Multi-omics profiling reveals peripheral blood biomarkers of multiple sclerosis: implications for diagnosis and stratification
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 12
作者:
Zhou, Qinming
;
Xie, Zuoquan
;
He, Lu
;
Sun, Guangqiang
;
Meng, Huanyu
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/10/21
multiple sclerosis
multi-omics
blood immune phenotyping
proteomic
metabolomic
clinically isolated syndrome
secondary progressive MS
Positive-Charge-Based Small Molecule Dyes for Gut Microbiota Fluorescent Imaging
期刊论文
OAI收割
ACS OMEGA, 2024, 卷号: 9, 期号: 34, 页码: 36371-36379
作者:
Liu, Yue
;
Wang, Zhiming
;
Li, Ke
;
Song, Ruihu
;
Xu, Zhiqiang
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/09/26
Isoindoline-based fluorogenic probes bearing a self-immolative linker for the sensitive and selective detection of O-GlcNAcase activity
期刊论文
OAI收割
CHEMICAL COMMUNICATIONS, 2024, 卷号: 60, 期号: 63, 页码: 8240-8243
作者:
Wu, Yuan-Hao
;
Wang, Guan-Jun
;
Guo, Chen
;
Wang, Pei-Pei
;
Wang, Jun-Yi
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/08/22
Stereospecific Synthesis and Biological Evaluation of KRN7000 Analogues with Thio-modifications at the Acyl Moiety
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2024, 页码: 7
作者:
Hao, Tianhui
;
Mi, Tian
;
Chu, Qinyu
;
Ma, Wenjing
;
Cheng, Xi
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/07/12
Glycolipid
KRN7000
stereospecific alpha-galactosylation
Th1/Th2 cytokines
molecular docking
A comprehensive assessment indicator of the water-energy-food nexus system based on the material consumption relationship
期刊论文
OAI收割
JOURNAL OF HYDROLOGY, 2024, 卷号: 633, 页码: 15
作者:
Hao, Lingang
;
Yu, Jingjie
;
Wang, Ping
;
Han, Chunhui
;
Gojenko, Boris
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/05/20
Systems science
Material flow
Water-energy-food nexus
Comprehensive indicators
The Amu Darya River basin