中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共28条,第1-10条 帮助

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PEGylation of Dipeptide Linker Improves Therapeutic Index and Pharmacokinetics of Antibody-Drug Conjugates 期刊论文  OAI收割
BIOCONJUGATE CHEMISTRY, 2025, 页码: 11
作者:  
Long, Jing;  Shao, Ting;  Wang, Yongmei;  Chen, Tianzhi;  Chen, Yuning
  |  收藏  |  浏览/下载:14/0  |  提交时间:2025/04/01
Simultaneous Quantification of Total Antibody and Conjugated Payload for DS001 in Rat Serum Using a Hybrid Immuno-Capture LC-MS/MS 期刊论文  OAI收割
AAPS JOURNAL, 2025, 卷号: 27, 期号: 1, 页码: 13
作者:  
Yu, Xiong;  Li, Weiqiang;  Huang, Wensi;  Xiao, Bo;  Long, Jing
  |  收藏  |  浏览/下载:5/0  |  提交时间:2025/04/01
Discovery of a Potent, selective and orally bioavailable CDK9 degrader for targeting transcription regulation in Triple-Negative breast cancer 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 16
作者:  
Nie, Hui-Jun;  Li, Ben-Fu;  Sun, Jingya;  Yuan, Yali;  Zhang, Zhi-Gao
  |  收藏  |  浏览/下载:9/0  |  提交时间:2024/11/26
Discovery of Orally Bioavailable and Potent CDK9 Inhibitors for Targeting Transcription Regulation in Triple-Negative Breast Cancer 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 12, 页码: 10035-10056
作者:  
Wang, Wen-Jing;  Gao, Lixin;  Wang, Simei;  Huang, Wensi;  Meng, Xin-Yu
  |  收藏  |  浏览/下载:6/0  |  提交时间:2024/08/20
Cross-ancestry genome-wide association studies of brain imaging phenotypes 期刊论文  OAI收割
NATURE GENETICS, 2024, 页码: 31
作者:  
Fu, Jilian;  Zhang, Quan;  Wang, Jianhua;  Wang, Meiyun;  Zhang, Bing
  |  收藏  |  浏览/下载:26/0  |  提交时间:2024/06/29
Metabolism investigation of the peptide-drug conjugate LN005 in rats using UHPLC-HRMS 期刊论文  OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 238, 页码: 11
作者:  
Wang, Weiqiang;  Chen, Chong;  Luo, Jing;  Tang, Chongzhuang;  Zheng, Yuandong
  |  收藏  |  浏览/下载:37/0  |  提交时间:2024/01/16
Metabolite characterisation of the peptide-drug conjugate LN005 in liver S9s by UHPLC-Orbitrap-HRMS 期刊论文  OAI收割
XENOBIOTICA, 2024, 页码: 9
作者:  
Yuan, Yali;  Wang, Weiqiang;  Luo, Jing;  Tang, Chongzhuang;  Zheng, Yuandong
  |  收藏  |  浏览/下载:20/0  |  提交时间:2024/02/19
A potent PGK1 antagonist reveals PGK1 regulates the production of IL-1 beta and IL-6 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 11, 页码: 4180-4192
作者:  
Liao, Liping;  Dang, Wenzhen;  Lin, Tingting;  Yu, Jinghua;  Liu, Tonghai
  |  收藏  |  浏览/下载:31/0  |  提交时间:2023/04/10
Pharmacokinetics, mass balance, and metabolism of [C-14]TPN171, a novel PDE5 inhibitor, in humans for the treatment of pulmonary arterial hypertension 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 13
作者:  
He, Yi-fei;  Liu, Yin;  Yu, Jing-hua;  Cheng, Huan;  Odilov, Abdullajon
  |  收藏  |  浏览/下载:42/0  |  提交时间:2022/08/16
Two Novel Rare Earth Coordination Polymers Derived from Zwitterionic 1,3-Bis(1-carboxylatoethyl)imidazolium Bromide: Structures and Magnetic Properties 期刊论文  OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2022, 卷号: 1250, 页码: 8
作者:  
Liu, Mengchen;  Yin, Qianqian;  Zhong, Shengnan;  Sun, Huimin;  Wang, Yibo
  |  收藏  |  浏览/下载:46/0  |  提交时间:2022/06/15