中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共105条,第1-10条 帮助

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Structural optimization of phthalazine derivatives for anti-HBV activities to improve oral bioavailability 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 10
作者:  
Yang, Yurong;  Xiao, Fuling;  Zuo, Jianping;  Yang, Li;  Hu, Youhong
  |  收藏  |  浏览/下载:1/0  |  提交时间:2025/08/20
Design and synthesis of CDK9/EZH2 dual-target inhibitors to achieve synergistic antitumor effects 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 14
作者:  
Tian, Lina;  Xiao, Jian;  Zeng, Yanping;  Li, Yangsha;  Wei, Aihuan
  |  收藏  |  浏览/下载:1/0  |  提交时间:2025/08/20
Discovery of potent anti-idiopathic pulmonary fibrosis (IPF) agents based on an o-aminopyridinyl alkynyl scaffold 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 15
作者:  
Wang, Yang;  Fan, Wenhui;  Guo, Yihao;  Sun, Li;  Hu, Youhong
  |  收藏  |  浏览/下载:8/0  |  提交时间:2025/08/20
Discovery of novel Ebola entry inhibitors with 1,2,3,4-tetrahydroisoquinoline-3-carboxamide based on (3S,4aS,8aS)-2-(3-amino-2-hydroxypropyl) decahydroisoquinoline-3-carboxamide scaffold 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 123, 页码: 4
作者:  
Lin, Junzhen;  Xiao, Fuling;  Han, Sheng;  Hu, Youhong;  Zuo, Jianping
  |  收藏  |  浏览/下载:15/0  |  提交时间:2025/06/23
Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradations 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 287, 页码: 10
作者:  
  |  收藏  |  浏览/下载:75/0  |  提交时间:2025/04/01
Diazonium-based derivatization for enhanced detection of phosphorylated metabolites by LC-MS in cells 期刊论文  OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2025, 卷号: 255, 页码: 7
作者:  
Wang, Yikang;  Lin, Feifei;  Zhu, Guozheng;  Zhou, Xiaoxue;  Hu, Youhong
  |  收藏  |  浏览/下载:28/0  |  提交时间:2025/04/01
Discovery of novel biaryl urea derivatives against IL-1/3 release with low toxicity based on NEK7 inhibitor 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 283, 页码: 12
作者:  
Wang, Leibo;  Zhu, Kehan;  Tian, Ziyang;  Wang, Haoyu;  Jia, Yulei
  |  收藏  |  浏览/下载:33/0  |  提交时间:2025/01/14
C(sp3)-H Carbonylative Cyclization of Hydrazones with CO2: Synthesis of Pyrazolone Derivatives 期刊论文  OAI收割
JOURNAL OF ORGANIC CHEMISTRY, 2024, 卷号: 89, 期号: 24, 页码: 18746-18751
作者:  
Wang, Kai;  Ouyang, Jun
  |  收藏  |  浏览/下载:20/0  |  提交时间:2025/01/14
Structural Optimization of Isoquinoline Derivatives from Lycobetaine and Their Inhibitory Activity against Neuroendocrine Prostate Cancer Cells 期刊论文  OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 18, 页码: 28
作者:  
Zhang, Zhuo;  Shen, Qianqian;  Ji, Yiyi;  Ma, Yanjie;  Hou, Haiyang
  |  收藏  |  浏览/下载:32/0  |  提交时间:2024/11/05
A novel BODIPY-based theranostic agent for in vivo fluorescence imaging of cerebral Aβ and ameliorating Aβ-associated disorders in Alzheimer's disease transgenic mice 期刊论文  OAI收割
RSC MEDICINAL CHEMISTRY, 2024, 页码: 9
作者:  
Zhang, Jingjing;  Ren, Wenming;  Liu, Xiaohui;  Chen, Jingjing;  Zeng, Yuteng
  |  收藏  |  浏览/下载:20/0  |  提交时间:2024/05/07