机构

• 上海药物研究所 [101]
• 化学研究所 [1]

采集方式

• OAI收割 [102]

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浏览/检索结果: 共102条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery of novel Ebola entry inhibitors with 1,2,3,4-tetrahydroisoquinoline-3-carboxamide based on (3S,4aS,8aS)-2-(3-amino-2-hydroxypropyl) decahydroisoquinoline-3-carboxamide scaffold 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 123, 页码: 4 作者:  Lin, Junzhen;  Xiao, Fuling;  Han, Sheng;  Hu, Youhong;  Zuo, Jianping   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/06/23 Ebola virus entry inhibitor  Tetrahydroisoquinoline   Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradations 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 287, 页码: 10 作者:  Zeng, Yanping;  Xiao, Jian;  Shi, Li;  Li, Yangsha;  Xu, Yuanxin   |  收藏  |  浏览/下载：57/0  |  提交时间：2025/04/01 LC3B  CDK9  Degradation  Protein complex   Diazonium-based derivatization for enhanced detection of phosphorylated metabolites by LC-MS in cells 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2025, 卷号: 255, 页码: 7 作者:  Wang, Yikang;  Lin, Feifei;  Zhu, Guozheng;  Zhou, Xiaoxue;  Hu, Youhong   |  收藏  |  浏览/下载：9/0  |  提交时间：2025/04/01 Phosphorylated metabolite  Derivatization  Chromatographic separation  Quantitative analysis  LC-MS   Discovery of novel biaryl urea derivatives against IL-1/3 release with low toxicity based on NEK7 inhibitor 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 283, 页码: 12 作者:  Wang, Leibo;  Zhu, Kehan;  Tian, Ziyang;  Wang, Haoyu;  Jia, Yulei   |  收藏  |  浏览/下载：13/0  |  提交时间：2025/01/14 NLRP3 inflammasome  NEK7  NLRP3-NEK7  Inhibitors   C(sp3)-H Carbonylative Cyclization of Hydrazones with CO2: Synthesis of Pyrazolone Derivatives 期刊论文  OAI收割 JOURNAL OF ORGANIC CHEMISTRY, 2024, 卷号: 89, 期号: 24, 页码: 18746-18751 作者:  Wang, Kai;  Ouyang, Jun;  Liu, Huan;  Yin, Lijun;  Yang, Kuoqi   |  收藏  |  浏览/下载：5/0  |  提交时间：2025/01/14 Structural Optimization of Isoquinoline Derivatives from Lycobetaine and Their Inhibitory Activity against Neuroendocrine Prostate Cancer Cells 期刊论文  OAI收割 MOLECULES, 2024, 卷号: 29, 期号: 18, 页码: 28 作者:  Zhang, Zhuo;  Shen, Qianqian;  Ji, Yiyi;  Ma, Yanjie;  Hou, Haiyang   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/11/05 NEPC  natural product  natural product derivatives  lycobetaine   A novel BODIPY-based theranostic agent for in vivo fluorescence imaging of cerebral Aβ and ameliorating Aβ-associated disorders in Alzheimer's disease transgenic mice 期刊论文  OAI收割 RSC MEDICINAL CHEMISTRY, 2024, 页码: 9 作者:  Zhang, Jingjing;  Ren, Wenming;  Liu, Xiaohui;  Chen, Jingjing;  Zeng, Yuteng   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/05/07 A novel phthalazinone derivative as a capsid assembly modulator inhibits hepatitis B virus expression 期刊论文  OAI收割 ANTIVIRAL RESEARCH, 2024, 卷号: 221, 页码: 14 作者:  Yang, Li;  Gong, Ying;  Liu, Feifei;  Chen, Wuhong;  Wang, Xinran   |  收藏  |  浏览/下载：35/0  |  提交时间：2024/02/19 Hepatitis B virus  Capsid assembly  Phthalazinone derivatives  Apoptosis   Degradation of Cyclin-Dependent Kinase 9/Cyclin T1 by Optimized Microtubule-Associated Protein 1 Light Chain 3 Beta-Recruiting Coumarin Analogs 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 17 作者:  Zeng, Yanping;  Xiao, Jian;  Xu, Yuanxin;  Wei, Fan;  Tian, Lina   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17 A prodrug of the capsid assembly modulator improved druggability and lowing HBsAg and HBeAg for the treatment of chronic hepatitis B 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 8 作者:  Chen, Wuhong;  Gong, Ying;  Long, Guozhang;  Wang, Xinran;  Yang, Yurong   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/10/17 HBV  Capsid assembly modulators  Prodrug  Hepatitis B surface antigen