机构

• 上海药物研究所 [36]
• 昆明植物研究所 [34]
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• OAI收割 [306]
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• 期刊论文 [314]
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• 2025 [2]
• 2024 [8]
• 2023 [9]
• 2022 [28]
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学科主题

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浏览/检索结果: 共317条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 One stone two birds: Introducing piperazine into a series of nucleoside derivatives as potent and selective PRMT5 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 18 作者:  Li, Huaxuan;  Yang, Hong;  Liu, Li;  Zheng, Jiahong;  Shi, Qiongyu   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/12/11 Protein arginine methyltransferase 5  Nucleoside derivatives  Piperazine  Metabolic stability  Symmetric dimethylarginines   Auto-RapTAC: A Versatile and Sustainable Platform for the Automated Rapid Synthesis and Evaluation of PROTAC 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 15 作者:  Chen, Jiexuan;  Wu, Mingfei;  Mo, Jun;  Hong, Ju;  Wang, Wei   |  收藏  |  浏览/下载：18/0  |  提交时间：2025/04/01 Discovery of CZL-046 with an (S)-3-Fluoropyrrolidin-2-one Scaffold as a p300 Bromodomain Inhibitor for the Treatment of Multiple Myeloma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 20, 页码: 18606-18628 作者:  Chen, Zonglong;  Yang, Hong;  Zhang, Yan;  Lyu, Xiaodong;  Shi, Qiongyu   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/11/05 Gut microbiota-brain bile acid axis orchestrates aging-related neuroinflammation and behavior impairment in mice 期刊论文  OAI收割 PHARMACOLOGICAL RESEARCH, 2024, 卷号: 208, 页码: 15 作者:  Ma, Junli;  Li, Mingxiao;  Bao, Yiyang;  Huang, Wenjin;  He, Xiaofang   |  收藏  |  浏览/下载：26/0  |  提交时间：2024/10/21 aging  brain  neuro-impairment  bile acid  gut microbiota   Transcriptomic decoding of regional cortical vulnerability to major depressive disorder 期刊论文  OAI收割 COMMUNICATIONS BIOLOGY, 2024, 卷号: 7, 期号: 1, 页码: 12 作者:  Zhu, Jiajia;  Chen, Xiao;  Lu, Bin;  Li, Xue-Ying;  Wang, Zi-Han   |  收藏  |  浏览/下载：21/0  |  提交时间：2024/09/10 Anti-HBV Activities of Cembranoids from the South China Sea Soft Coral Sinularia pedunculata and Their Structure Activity Relationship 期刊论文  OAI收割 CHEMISTRY & BIODIVERSITY, 2024, 页码: 8 作者:  Huang, Chao;  Jin, Yang;  Sun, Ruo-Nan;  Hu, Kong-Ying;  Yao, Li-Gong   |  收藏  |  浏览/下载：76/0  |  提交时间：2024/08/22 Hepatitis B Virus  cembranoid  anti-HBV activity  structure-activity relationship  ENI/Xp enhancer/promoter   Oncogenic KRAS Induces Arginine Auxotrophy and Confers a Therapeutic Vulnerability to SLC7A1 Inhibition in Non-Small Cell Lung Cancer 期刊论文  OAI收割 CANCER RESEARCH, 2024, 卷号: 84, 期号: 12, 页码: 1963-1977 作者:  Gai, Xiameng;  Liu, Yingluo;  Lan, Xiaojing;  Chen, Luoyi;  Yuan, Tao   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/08/20 Size, distribution, and vulnerability of the global soil inorganic carbon 期刊论文  OAI收割 SCIENCE, 2024, 卷号: 384, 期号: 6692, 页码: 233-239 作者:  Huang, Yuanyuan;  Song, Xiaodong;  Wang, Ying-Ping;  Canadell, Josep G.;  Luo, Yiqi   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/08/22 Article Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation 期刊论文  OAI收割 CELL REPORTS MEDICINE, 2024, 卷号: 5, 期号: 3, 页码: 25 作者:  Zhu, Weize;  Hong, Ying;  Tong, Zhaowei;  He, Xiaofang;  Li, Yan   |  收藏  |  浏览/下载：36/0  |  提交时间：2024/06/27 Regioselective Deacetylation of Peracetylated Deoxy-C-glycopyranosides by Boron Trichloride (BCl3) 期刊论文  OAI收割 JOURNAL OF ORGANIC CHEMISTRY, 2024, 页码: 16 作者:  Chen, Shuangyuan;  Wei, Feifei;  Cheng, Xinqiang;  Luo, Ying;  Meng, Fancui   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/05/07