中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
水生生物研究所 [1]
采集方式
OAI收割 [9]
内容类型
期刊论文 [9]
发表日期
2025 [1]
2024 [5]
2023 [1]
2022 [1]
2020 [1]
学科主题
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Simultaneous Quantification of Total Antibody and Conjugated Payload for DS001 in Rat Serum Using a Hybrid Immuno-Capture LC-MS/MS
期刊论文
OAI收割
AAPS JOURNAL, 2025, 卷号: 27, 期号: 1, 页码: 13
作者:
Yu, Xiong
;
Li, Weiqiang
;
Huang, Wensi
;
Xiao, Bo
;
Long, Jing
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/04/01
ADC
LC-MS/MS
payload
simultaneous quantification
total antibody
Discovery of a Potent, selective and orally bioavailable CDK9 degrader for targeting transcription regulation in Triple-Negative breast cancer
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 16
作者:
Nie, Hui-Jun
;
Li, Ben-Fu
;
Sun, Jingya
;
Yuan, Yali
;
Zhang, Zhi-Gao
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/11/26
Triple-negative breast cancer
Targeting transcription regulation
Orally bioavailable degrader
PROTAC
Cyclin-dependent Kinase 9
Digital colloid-enhanced Raman spectroscopy for the pharmacokinetic detection of bioorthogonal drugs
期刊论文
OAI收割
CHEMICAL SCIENCE, 2024, 页码: 11
作者:
Bi, Xinyuan
;
He, Zhicheng
;
Luo, Zhewen
;
Huang, Wensi
;
Diao, Xingxing
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/09/26
Discovery of Orally Bioavailable and Potent CDK9 Inhibitors for Targeting Transcription Regulation in Triple-Negative Breast Cancer
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 12, 页码: 10035-10056
作者:
Wang, Wen-Jing
;
Gao, Lixin
;
Wang, Simei
;
Huang, Wensi
;
Meng, Xin-Yu
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/08/20
A validated LC-MS/MS method for the quantitation of daratumumab in rat serum using rapid tryptic digestion without IgG purification and reduction
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 243, 页码: 8
作者:
Li, Weiqiang
;
Huang, Wensi
;
Yu, Xiong
;
Chen, Chong
;
Yuan, Yali
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/05/22
Daratumumab
LC-MS/MS
Surrogate peptide
Pharmacokinetics
Pharmacokinetics and metabolite identification of 23-hydroxybetulinic acid in rats by using liquid chromatography-mass spectrometry method
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2024, 卷号: 1234, 页码: 10
作者:
Xue, Mingzhen
;
Yang, Cheng
;
Huang, Wensi
;
He, Yifei
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/05/22
23-hydroxybetulinic acid
Pharmacokinetics
Metabolism
UPLC-MS
LC-MS/MS
Integrative multi-omics and drug-response characterization of patient-derived prostate cancer primary cells
期刊论文
OAI收割
Signal Transduction and Targeted Therapy, 2023, 卷号: 8, 期号: 6, 页码: 3013-3028
作者:
Wang, Ziruoyu
;
Li, Yanan
;
Zhao, Wensi
;
Jiang, Shuai
;
Huang, Yuqi
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/03/27
Drug repurposing for cancer treatment through global propagation with a greedy algorithm in a multilayer network
期刊论文
OAI收割
CANCER BIOLOGY & MEDICINE, 2022, 卷号: 19, 期号: 1, 页码: 74-+
作者:
Cheng, Xi
;
Zhao, Wensi
;
Zhu, Mengdi
;
Wang, Bo
;
Wang, Xuege
  |  
收藏
  |  
浏览/下载:271/0
  |  
提交时间:2024/03/21
Database
drug repurposing
machine learning
network random walk
proteomics analysis
Function and association analysis of Cyclophilin A gene with resistance to Edwardsiella ictaluri in yellow catfish
期刊论文
OAI收割
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2020, 卷号: 113, 页码: 8
作者:
Xiong, Yang
;
Zheng, Xiaozhen
;
Ke, Wensi
;
Gong, Gaorui
;
Wang, Yuhong
  |  
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2020/12/01
CypA
Yellow catfish
Edwardsiella ictaluri
Transgenic
SNP association Analysis