中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
重庆绿色智能技术研究... [5]
采集方式
OAI收割 [13]
内容类型
期刊论文 [13]
发表日期
2025 [1]
2024 [2]
2023 [1]
2022 [4]
2021 [1]
2020 [2]
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Harnessing the Magic Methyl Effect: Discovery of CLPP-2068 as a Novel
Hs
ClpP Activator for the Treatment of Diffuse Large B-Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 4, 页码: 4287-4307
作者:
Sun, Mingyang
;
Chen, Beijing
;
Teng, Dan
;
Zhao, Hongshen
;
Liao, Yilie
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/04/01
Discovery of CLPP-1071 as an Exceptionally Potent and Orally Efficacious Human ClpP Activator with Strong In Vivo Antitumor Activity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21
作者:
Chen, Beijing
;
Sun, Mingyang
;
Zhang, Chun
;
Huang, Qi
;
Teng, Dan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/12/25
Discovery of Preclinical Candidate AD1058 as a Highly Potent, Selective, and Brain-Penetrant ATR Inhibitor for the Treatment of Advanced Malignancies
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12735-12759
作者:
Liu, Zhi
;
Jiang, Kailong
;
Liu, Yan
;
Li, Junfei
;
Huang, Siqi
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/09/26
A comprehensive analysis of the Bencao (herbal) small RNA Atlas reveals novel RNA therapeutics for treating human diseases
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 19
作者:
Cao, Yinghao
;
Lin, Yexuan
;
Sun, Na
;
Du, Xinyi
;
Dong, Yixin
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2023/10/17
small RNA
herbal decoction
cross-kingdom regulation
traditional Chinese medicine
RNA oligonucleotide drug
RNA therapeutics
Bencao small RNA Atlas
Superhydrophobic Materials: Versatility and Translational Applications
期刊论文
OAI收割
ADVANCED MATERIALS INTERFACES, 2022, 页码: 29
作者:
Yong, Haiyang
;
Li, Zhili
;
Huang, Xiaobei
;
Wang, Kaixuan
;
Zhou, Ya-Nan
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2022/10/14
fabrication technology
practical application
superhydrophobic material
versatility
Targeted delivery and enhanced uptake of chemo-photodynamic nanomedicine for melanoma treatment
期刊论文
OAI收割
ACTA BIOMATERIALIA, 2022, 卷号: 147, 页码: 356-365
作者:
Huang, Xiaobei
;
Mu, Ning
;
Ding, Yuanfu
;
Lam, Hou Wang
;
Yue, Ludan
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/08/22
Photodynamic-chemotherapeutic therapy
Pt(IV) prodrug
Charge -reversal
Targeted drug delivery
Controlled drug release
Genetic Engineering of Adipose-Derived Stem Cells Using Biodegradable and Lipid-Like Highly Branched Poly(beta-amino ester)s
期刊论文
OAI收割
ACS MACRO LETTERS, 2022, 卷号: 11, 期号: 5, 页码: 636-642
作者:
Li, Qiuxia
;
Sun, Litao
;
Huang, Xiaobei
;
Liu, Shuai
;
Yong, Haiyang
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/08/22
Cyclic poly(beta-amino ester)s with enhanced gene transfection activity synthesized through intra-molecular cyclization
期刊论文
OAI收割
CHEMICAL COMMUNICATIONS, 2022, 页码: 4
作者:
Wang, Chenfei
;
Huang, Xiaobei
;
Sun, Litao
;
Li, Qiuxia
;
Li, Zhili
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/08/22
Supramolecular micelles as multifunctional theranostic agents for synergistic photodynamic therapy and hypoxia-activated chemotherapy
期刊论文
OAI收割
ACTA BIOMATERIALIA, 2021, 卷号: 131, 页码: 483-492
作者:
Huang, Xiaobei
;
Chen, Tunan
;
Mu, Ning
;
Lam, Hou Wang
;
Sun, Chen
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/10/13
Photodynamic-chemotherapeutic therapy
Supramolecular
Hypoxia-activated prodrug
Targeted drug delivery
Controlled drug release
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:
Che, Jinxin
;
Huang, Feng
;
Zhang, Mengmeng
;
Xu, Gaoya
;
Qu, Bingxue
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2020/12/21
Metabolic pathways
Isocitrate dehydrogenase 2
Conformational restriction
Macrocyclic derivatives
Inhibitors