机构

• 上海药物研究所 [13]
• 南京地理与湖泊研究所 [1]

采集方式

• OAI收割 [14]

内容类型

• 期刊论文 [14]

发表日期

• 2026 [1]
• 2025 [3]
• 2024 [3]
• 2023 [1]
• 2022 [1]
• 2021 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共14条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序作者升序作者降序 Novel thieno[2,3-b]pyridine derivatives protect islet through DRAK2 kinase inhibition 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 301, 页码: 18 作者:  Lian, Kaiyue;  Li, Ruihan;  Lu, Yuting;  Song, Gaolei;  Zhang, Xinwen   |  收藏  |  浏览/下载：3/0  |  提交时间：2025/12/04 DRAK2  Inhibitor  Thieno[2  b ]pyridine  Diabetes   The enedioic acid analog 326E alleviates metabolic dysfunction-associated steatohepatitis via dual targeting at ACLY and PPARα 期刊论文  OAI收割 CELL METABOLISM, 2025, 卷号: 37, 期号: 11, 页码: 2149-2166 作者:  Xie, Zhifu;  Cheng, Long;  Hu, Yue;  Song, Gaolei;  Wang, Fan   |  收藏  |  浏览/下载：1/0  |  提交时间：2026/01/28 Discovery of Novel Tridentate Alkenyl Diacid Derivatives as Potent ATP Citrate Lyase Inhibitors for the Treatment of Hepatocellular Carcinoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 15, 页码: 15598-15616 作者:  Yang, Yurou;  Zhai, Jimao;  Wang, Fan;  Song, Gaolei;  Xu, Honghong   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/09/09 A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics of BGT-002, a Novel ATP-Citrate Lyase Inhibitor, in Healthy Chinese Subjects 期刊论文  OAI收割 DRUG DESIGN DEVELOPMENT AND THERAPY, 2025, 卷号: 19, 页码: 1783-1794 作者:  Liu, Yun;  Yu, Chengyin;  Zhang, Yifan;  Xie, Zhifu;  Wang, Yating   |  收藏  |  浏览/下载：28/0  |  提交时间：2025/04/24 safety  tolerability  pharmacokinetics  pharmacodynamics  BGT-002  novel ACLY inhibitor   Discovery of Alkyl Conjugated Diene Diacids as Novel ACLY Inhibitors 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2024, 卷号: 44, 期号: 11, 页码: 3476-3489 作者:  Cheng, Tingting;  Song, Gaolei;  Cheng, Long;  Wang, Fan;  Sun, Xinyu   |  收藏  |  浏览/下载：62/0  |  提交时间：2025/02/28 metabolic diseases  ATP-citrate lyase (ACLY)  lipogenesis  ACLY inhibitors  dienyldicarboxylic acid   Simultaneous determination of BGT-002 and its acyl glucuronide metabolite ZM326E-M2 in human plasma by liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 243, 页码: 8 作者:  Zhu, Xueran;  Cui, Shumin;  Liu, Xinjing;  Zhang, Mei;  Xie, Zhifu   |  收藏  |  浏览/下载：41/0  |  提交时间：2024/05/31 ATP-Citrate Lyase  BGT-002  Acyl glucuronide metabolite  Pseudo-MRM  LC-MS/MS  Pharmacokinetics   Polyphenol Compound 18a Modulates UCP1-Dependent Thermogenesis to Counteract Obesity 期刊论文  OAI收割 BIOMOLECULES, 2024, 卷号: 14, 期号: 6, 页码: 21 作者:  Wen, Xueping;  Song, Yufei;  Zhang, Mei;  Kang, Yiping;  Chen, Dandan   |  收藏  |  浏览/下载：53/0  |  提交时间：2024/08/22 18a  adipocytes  polyphenols  thermogenesis  UCP1   Development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 2, 页码: 739-753 作者:  Xie, Zhifu;  Zhang, Mei;  Song, Qian;  Cheng, Long;  Zhang, Xinwen   |  收藏  |  浏览/下载：55/0  |  提交时间：2024/03/27 Hypercholesterolemia  Atherosclerosis  Liver  ATP-Citrate lyase (ACLY)  Lipogenesis  Cholesterol efflux  ACLY inhibitor   Lignin-containing hydrogel matrices with enhanced adhesion and toughness for all-hydrogel supercapacitors 期刊论文  OAI收割 CHEMICAL ENGINEERING JOURNAL, 2022, 卷号: 450 作者:  Wang, Dingkun;  Yang, Fusheng;  Cong, Lulu;  Feng, Wanglong;  Wang, Chunpeng   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/12/19 Design and Synthesis of Alkyl Phenols Inhibitors of Death Associated Apoptotic Protein Kinase 2 (DRAK2) 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3204-3213 作者:  Zheng Zhang;  Dai Chengqiu;  Wu Honghong;  Li Jingya;  Nan Fajun   |  收藏  |  浏览/下载：61/0  |  提交时间：2021/11/04 death associated apoptotic protein kinase 2  diabetes  alkylphenols  inhibitors