中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
生态环境研究中心 [24]
上海药物研究所 [1]
合肥物质科学研究院 [1]
采集方式
OAI收割 [26]
内容类型
期刊论文 [26]
发表日期
2022 [1]
2021 [2]
2020 [6]
2019 [1]
2018 [4]
2017 [2]
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Structure-based rational design enables efficient discovery of a new selective and potent AKT PROTAC degrader
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 238, 页码: 15
作者:
Zhu, Cheng-Liang
;
Luo, Xiaomin
;
Tian, Tian
;
Rao, Zijian
;
Wang, Hanlin
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/08/16
AKT
Protein kinase B
PROTAC
Chemical degrader
Rational design
Cytotoxicity, mitochondrial impairment, DNA damage and associated mechanisms induced by tris(1,3-dichloro-2-propyl) phosphate and tris (2-butoxyethyl) phosphate in A549 cells
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2021, 卷号: 787, 页码: -
作者:
Yuan, Shengwu
;
Ma, Mei
;
Zhu, Xiaoshan
;
Han, Yingnan
;
Rao, Kaifeng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2021/12/23
Phosphorus-containing flame retardants
Cellular damage
Cell cycle arrest
Oxidative stress
p53
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
期刊论文
OAI收割
AUTOPHAGY, 2021, 卷号: 17
作者:
Klionsky, Daniel J.
;
Abdel-Aziz, Amal Kamal
;
Abdelfatah, Sara
;
Abdellatif, Mahmoud
;
Abdoli, Asghar
  |  
收藏
  |  
浏览/下载:283/0
  |  
提交时间:2021/05/31
Autophagosome
cancer
flux
LC3
lysosome
macroautophagy
neurodegeneration
phagophore
stress
vacuole
Distribution, sources and transport of organophosphorus flame retardants in the water and sediment of Ny-Alesund, Svalbard, the Arctic
期刊论文
OAI收割
ENVIRONMENTAL POLLUTION, 2020, 卷号: 264, 页码: 1-8
作者:
Gao, Xiaozhong
;
Xu, Yiping
;
Ma, Mei
;
Huang, Qinghui
;
Gabrielsen, Geir Wing
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/09/15
Organophosphorus flame retardants
The Arctic
Passive sampling
Water
Spatial distribution
Tricresyl phosphate isomers exert estrogenic effects via G protein-coupled estrogen receptor-mediated pathways
期刊论文
OAI收割
ENVIRONMENTAL POLLUTION, 2020, 卷号: 264, 页码: 1-10
作者:
Ji, Xiaoya
;
Li, Na
;
Ma, Mei
;
Rao, Kaifeng
;
Yang, Rong
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/09/15
Tricresyl phosphate isomers
Estrogenic effect
GPER
cAMP
Calcium mobilization
In vitro estrogen-disrupting effects of organophosphate flame retardants
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 727, 页码: 1-10
作者:
Ji, Xiaoya
;
Li, Na
;
Ma, Mei
;
Rao, Kaifeng
;
Wang, Zijian
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2021/09/15
OPFRs
Estrogen-disrupting effects
ER alpha
Yeast two-hybrid assay
MVLN cell assay
E-SCREEN assay
Tissue-specific bioaccumulation, metabolism and excretion of tris (2-ethylhexyl) phosphate (TEHP) in rare minnow (Gobiocyprisrarus)
期刊论文
OAI收割
ENVIRONMENTAL POLLUTION, 2020, 卷号: 261, 页码: 1-9
作者:
Hou, Rui
;
Xu, Yiping
;
Rao, Kaifeng
;
Feng, Chenglian
;
Wang, Zijian
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/09/15
Tris (2-ethylhexyl) phosphate (TEHP)
Bioaccumulation
Toxicokinetic
Metabolite parent concentration factor
In vivo metabolism
In vitro oxidative stress, mitochondrial impairment and G1 phase cell cycle arrest induced by alkyl-phosphorus-containing flame retardants
期刊论文
OAI收割
CHEMOSPHERE, 2020, 卷号: 248, 页码: 1-9
作者:
Yuan, Shengwu
;
Zhu, Kongrui
;
Ma, Mei
;
Zhu, Xiaoshan
;
Rao, Kaifeng
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/09/15
Phosphorus-containing flame retardants
Oxidative stress
DNA damage
Mitochondrial impairment
Cell apoptosis
The steroid receptor coactivator 1 (SRC1) and 3 (SRC3) recruitment as novel molecular initiating event of 4-n-nonylphenol in estrogen receptor alpha-mediated pathways
期刊论文
OAI收割
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 189, 页码: 1-8
作者:
Ji, Xiaoya
;
Li, Na
;
Yang, Rong
;
Rao, Kaifeng
;
Ma, Mei
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2021/09/15
4-n-Nonylphenol
Estrogenic activity
Molecular initiating event (MIE)
Estrogen receptor alpha (ER alpha)
Steroid receptor coactivator (SRC)
Aryl-phosphorus-containing flame retardants induce oxidative stress, the p53-dependent DNA damage response and mitochondrial impairment in A549 cells
期刊论文
OAI收割
ENVIRONMENTAL POLLUTION, 2019, 卷号: 250, 页码: 58-67
作者:
Yuan, Shengwu
;
Han, Yingnan
;
Ma, Mei
;
Rao, Kaifeng
;
Wang, Zijian
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/10/21
Phosphorus-containing flame retardants
Reactive oxygen species
Mitochondrial damage
p53 transfection
Gene expression