中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共178条,第1-10条 帮助

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Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11
作者:  
Guma, Samuel Desta;  Song, Kang;  Sun, Haiguo;  Yang, Lei;  Zhou, Zhaoyin
  |  收藏  |  浏览/下载:1/0  |  提交时间:2025/08/20
Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 20
作者:  
Zheng, Fuqiang;  Hu, Zhengtao;  Chen, Hai;  Cheng, Jiaxin;  Hou, Qiongqiong
  |  收藏  |  浏览/下载:23/0  |  提交时间:2025/06/23
Identification of Cannabigerol-Derived Dual CB2 Receptor Agonists and TRPM8 Antagonists with Anti-Inflammatory and Analgesic Activities 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 13, 页码: 13335-13357
作者:  
Yang, Wenjiao;  Sun, Haiguo;  Ji, Jing;  Chen, Hai;  Cheng, Jiaxin
  |  收藏  |  浏览/下载:1/0  |  提交时间:2025/08/20
An Asymmetric Reductive Amination Synthesis of Ritlecitinib Using (S)-α-Methylbenzylamine as Chiral Auxiliary 期刊论文  OAI收割
CHEMISTRY-A EUROPEAN JOURNAL, 2025, 页码: 10
作者:  
Dong, Hongkun;  Bonku, Emmanuel Mintah;  Zhang, Yuxuan;  Yang, Xingbang;  Abduahadi, Safomuddin
  |  收藏  |  浏览/下载:19/0  |  提交时间:2025/07/25
Design and Development of a Novel Oral 4′-Fluorouridine Double Prodrug VV261 against SFTSV 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 9, 页码: 9811-9826
作者:  
Cheng, Yong;  Zheng, Wei;  Dong, Xinru;  Sun, Tengxiao;  Xu, Mengwei
  |  收藏  |  浏览/下载:11/0  |  提交时间:2025/06/23
Design, Synthesis, and Biological Evaluation of Peptidomimetic Tetrahydropyrrole Spirodihydroindolones as SARS-CoV-2 3CL Protease Inhibitors 期刊论文  OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 16, 期号: 5, 页码: 790-796
作者:  
Hu, Liuyan;  Zhao, Zhi;  Zhang, Shujing;  Yang, Lei;  Cui, Wenjie
  |  收藏  |  浏览/下载:8/0  |  提交时间:2025/06/23
Structural Similarity in Natural Products Leading to Sample Misidentification: A Case Study of the Bisbenzylisoquinoline Alkaloids Oxyacanthine and Berbamine 期刊论文  OAI收割
JOURNAL OF NATURAL PRODUCTS, 2025, 卷号: 88, 期号: 1, 页码: 191-198
作者:  
Cheng, Yan;  Akramov, Davlat;  Yakhshilikova, Lola;  Zhu, Chengwei;  Lu, Jie
  |  收藏  |  浏览/下载:28/0  |  提交时间:2025/04/01
Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22
作者:  
Guma, Samuel Desta;  Zhou, Zhaoyin;  Song, Kang;  Yang, Feipu;  Suo, Jin
  |  收藏  |  浏览/下载:21/0  |  提交时间:2024/12/11
F-CPI: A Multimodal Deep Learning Approach for Predicting Compound Bioactivity Changes Induced by Fluorine Substitution 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 13
作者:  
Zhang, Qian;  Yin, Wenhai;  Chen, Xinyao;  Zhou, Aimin;  Zhang, Guixu
  |  收藏  |  浏览/下载:26/0  |  提交时间:2025/02/28
Direct Reductive N-alkylation of Amines with Carboxylic Esters 期刊论文  OAI收割
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2024, 页码: 7
作者:  
Zhang, Yuxuan;  Bonku, Emmanuel Mintah;  Yang, Xingbang;  Zhu, Fuqiang;  Jiang, Xiangrui
  |  收藏  |  浏览/下载:22/0  |  提交时间:2025/01/14