中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22
作者:
Guma, Samuel Desta
;
Zhou, Zhaoyin
;
Song, Kang
;
Yang, Feipu
;
Suo, Jin
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/12/11
SARS-CoV-2
3CL pro inhibitors
Peptidomimetics
Spiropyrrolidine derivatives
Numerical simulation of spray cooling heat transfer evolution based on experimental data
期刊论文
OAI收割
PHYSICS OF FLUIDS, 2024, 卷号: 36, 期号: 9, 页码: 21
作者:
Yang, Xin
;
Shen, Feng
;
Wang, Jia
;
Wu, Di
;
Duan, Longsheng
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/10/14
Discovery of Novel 1-Phenylpiperidine Urea-Containing Derivatives Inhibiting
β
-Catenin/BCL9 Interaction and Exerting Antitumor Efficacy through the Activation of Antigen Presentation of cDC1 Cells
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 36
作者:
Zhu, Wenhua
;
Liu, Cuiting
;
Xi, Kang
;
Li, Anqi
;
Shen, Li-an
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/08/20
Cross-ancestry genome-wide association studies of brain imaging phenotypes
期刊论文
OAI收割
NATURE GENETICS, 2024, 页码: 31
作者:
Fu, Jilian
;
Zhang, Quan
;
Wang, Jianhua
;
Wang, Meiyun
;
Zhang, Bing
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/06/29
Discovery of a brain-permeable bromodomain and extra terminal domain (BET) inhibitor with selectivity for BD1 for the treatment of multiple sclerosis
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 14
作者:
Chen, Xuetao
;
Wu, Tingting
;
Du, Zhiyan
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2024/02/27
BET
BD1
Bromodomain
Brain-permeable
Multiple sclerosis
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
Development and Test of On-Line Spectroscopic System Based on Thermostatic Control Using STM32 Single-Chip Microcomputer
期刊论文
OAI收割
SPECTROSCOPY AND SPECTRAL ANALYSIS, 2023, 卷号: 43
作者:
Huang Chao
;
Zhao Yu-hong
;
Zhang Hong-ming
;
Lu Bo
;
Yin Xiang-hui
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/11/17
On-line spectroscopic system
STM32 single-chip microcomputer
Proportional-integral-differential (PID) control
Pctra data acquisition
Modeling of flexible metal wheel for pressurized lunar rover and traction performance prediction
期刊论文
OAI收割
JOURNAL OF FIELD ROBOTICS, 2023
作者:
Zhu, Jianzhong
;
Shen, Yan
;
Hao, Pujun
;
Liu, Jingna
;
Li YQ(李玉琼)
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/09/26
flexible metal wheel
pressurized lunar rover
traction performance
wheel soil interaction model
Discovery of 1H-Imidazo[4,5-b]pyridine Derivatives as Potent and Selective BET Inhibitors for the Management of Neuropathic Pain
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 13, 页码: 8725-8744
作者:
Chen, Xuetao
;
Cao, Danyan
;
Liu, Chihong
;
Meng, Fanying
;
Zhang, Zijian
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/10/17
Intact regulation of G1/S transition renders esophageal squamous cell carcinoma sensitive to PI3Kα inhibitors
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 153
作者:
Zhang, Xu
;
Wang, Yuxiang
;
Zhang, Xi
;
Shen, Yanyan
;
Yang, Kang
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/03/27