中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [48]
大连化学物理研究所 [3]
近代物理研究所 [3]
中国科学院大学 [2]
新疆理化技术研究所 [1]
南京土壤研究所 [1]
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期刊论文 [59]
会议论文 [1]
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2025 [1]
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2022 [1]
2021 [2]
2019 [3]
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学科主题
物理化学 [1]
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Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22
作者:
Guma, Samuel Desta
;
Zhou, Zhaoyin
  |  
收藏
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浏览/下载:8/0
  |  
提交时间:2024/12/11
SARS-CoV-2
3CL pro inhibitors
Peptidomimetics
Spiropyrrolidine derivatives
F-CPI: A Multimodal Deep Learning Approach for Predicting Compound Bioactivity Changes Induced by Fluorine Substitution
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 13
作者:
Zhang, Qian
;
Yin, Wenhai
;
Chen, Xinyao
;
Zhou, Aimin
;
Zhang, Guixu
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/02/28
Synthesis and biological evaluation of multimodal monoaminergic arylpiperazine derivatives with potential antidepressant profile
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 16
作者:
Zheng, Jiefang
;
Zhou, Liping
;
Gong, Xudong
;
Yang, Feipu
;
Cheng, Jiaxin
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/08/22
Triple reuptake inhibitors
5-HT 1A R agonists
Antidepressants
Multimodal serotonergic compounds
Design, synthesis, and biological evaluation of novel 1-amido-2-one-4-thio-deoxypyranose as potential antitumor agents for multiple myeloma
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 111, 页码: 16
作者:
Li, Xiaomei
;
Zhang, Hui
;
Dong, Sanfeng
;
Gao, Xuejie
;
Sun, Haiguo
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/09/26
Multiple myeloma
1-amido-2-one-4-thio-deoxypyranose
TRIP13 inhibitor
In vivo activity
Direct esterification of amides by the dimethylsulfate-mediated activation of amide C-N bonds
期刊论文
OAI收割
COMMUNICATIONS CHEMISTRY, 2024, 卷号: 7, 期号: 1, 页码: 9
作者:
Qin, Hongjian
;
Han, Zijian
;
Bonku, Emmanuel Mintah
;
Sun, Haiguo
;
Odilov, Abdullajon
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/05/31
Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2
期刊论文
OAI收割
Signal Transduction and Targeted Therapy, 2023, 卷号: 8, 期号: 5, 页码: 2384-2391
作者:
Xu, Zhijian
;
Shi, Danrong
;
Han, Jianbao
;
Ling, Yun
;
Jiang, Xiangrui
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2024/03/27
Chemo- and Site-Selective Lysine Modification of Peptides and Proteins under Native Conditions Using the Water-Soluble Zolinium
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 14
作者:
Sun, Haiguo
;
Xi, Mengyu
;
Jin, Qiang
;
Zhu, Zhengdan
;
Zhang, Yani
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2022/09/30
Observations of Forbush Decreases of Cosmic-Ray Electrons and Positrons with the Dark Matter Particle Explorer
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2021, 卷号: 920, 期号: 2, 页码: 10
作者:
Alemanno, Francesca
;
An, Qi
;
Azzarello, Philipp
;
Barbato, Felicia Carla Tiziana
;
Bernardini, Paolo
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收藏
  |  
浏览/下载:106/0
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提交时间:2021/12/08
Solar coronal mass ejections
Forbush effect
Cosmic rays
One step stereoselective synthesis of oxazoline-fused saccharides and their conversion into the corresponding 1,2-cis glycosylamines bearing various protected groups
期刊论文
OAI收割
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 7, 页码: 1580-1588
作者:
Dong, Sanfeng
;
Zhao, Yitian
;
Shi, Yulong
;
Xu, Zhijian
;
Shen, Jingshan
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
Metal-free quinolylation of the primary amino groups of amino acid derivatives and peptides with dihydrooxazolo[3,2-a]quinoliniums
期刊论文
OAI收割
GREEN CHEMISTRY, 2019, 卷号: 21, 期号: 15, 页码: 4231-4237
作者:
Liu, Peng
;
Li, Bo
;
Xi, Mengyu
;
Chen, Zhaoqiang
;
Sun, Haiguo
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收藏
  |  
浏览/下载:37/0
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提交时间:2020/07/01