机构

• 上海药物研究所 [13]
• 天津工业生物技术研... [13]
• 生物物理研究所 [1]
• 上海有机化学研究所 [1]

采集方式

• OAI收割 [28]

内容类型

• 期刊论文 [28]

发表日期

• 2024 [1]
• 2022 [2]
• 2021 [3]
• 2020 [2]
• 2019 [2]
• 2018 [2]
• 更多

学科主题

• Cell Biolo... [1]
• 分析化学 [1]

筛选

浏览/检索结果: 共28条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Structural Mass Spectrometry Captures Residue-Resolved Comprehensive Conformational Rearrangements of a G Protein-Coupled Receptor 期刊论文  OAI收割 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 卷号: 146, 期号: 29, 页码: 20045-20058 作者:  Liu, Hongyue;  Yan, Pengfei;  Zhang, Zhaoyu;  Han, Hongbo;  Zhou, Qingtong   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/09/26 Nanobodies and chemical cross-links advance the structural and functional analysis of PI3K alpha 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119, 期号: 38, 页码: 9 作者:  Hart, Jonathan R.;  Liu, Xiao;  Pan, Chen;  Liang, Anyi;  Ueno, Lynn   |  收藏  |  浏览/下载：23/0  |  提交时间：2023/10/17 phosphoinositide 3-kinase (PI3K)  nanobody  conformational changes  chemical cross-linking  mass spectrometry   Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1 期刊论文  OAI收割 NATURE, 2022, 页码: 24 作者:  Qu, Xiangli;  Qiu, Na;  Wang, Mu;  Zhang, Bingjie;  Du, Juan   |  收藏  |  浏览/下载：46/0  |  提交时间：2022/06/15 Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening 期刊论文  OAI收割 BIOMOLECULES, 2021, 卷号: 11, 期号: 7, 页码: 14 作者:  Zhou, Qingtong;  Guo, Wanjing;  Dai, Antao;  Cai, Xiaoqing;  Vass, Marton   |  收藏  |  浏览/下载：44/0  |  提交时间：2021/08/17 GLP-1R  virtual screening  allosteric modulator  drug discovery  molecular docking   Affinity Mass Spectrometry-Based Fragment Screening Identified a New Negative Allosteric Modulator of the Adenosine A(2A) Receptor Targeting the Sodium Ion Pocket 期刊论文  OAI收割 ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 6, 页码: 991-1002 作者:  Lu, Yan;  Liu, Hongyue;  Yang, Dehua;  Zhong, Li;  Xin, Ye   |  收藏  |  浏览/下载：63/0  |  提交时间：2021/08/17 G protein-coupled receptors: structure- and function-based drug discovery 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 27 作者:  Yang, Dehua;  Zhou, Qingtong;  Labroska, Viktorija;  Qin, Shanshan;  Darbalaei, Sanaz   |  收藏  |  浏览/下载：37/0  |  提交时间：2021/05/24 Targeted Proteomics Combined with Affinity Mass Spectrometry Analysis Reveals Antagonist E7 Acts As an Intracellular Covalent Ligand of Orphan Receptor GPR52 期刊论文  OAI收割 ACS CHEMICAL BIOLOGY, 2020, 卷号: 15, 期号: 12, 页码: 3275-3284 作者:  Ma, Mengna;  Guo, Shimeng;  Lin, Xi;  Li, Shanshan;  Wu, Yiran   |  收藏  |  浏览/下载：37/0  |  提交时间：2021/05/24 A Novel G Protein-Biased and Subtype-Selective Agonist for a G Protein-Coupled Receptor Discovered from Screening Herbal Extracts 期刊论文  OAI收割 ACS CENTRAL SCIENCE, 2020, 卷号: 6, 期号: 2, 页码: 213-225 作者:  Zhang, Bingjie;  Zhao, Simeng;  Yang, Dehua;  Wu, Yiran;  Xin, Ye   |  收藏  |  浏览/下载：39/0  |  提交时间：2020/07/01 Accelerating the Throughput of Affinity Mass Spectrometry-Based Ligand Screening toward a G Protein-Coupled Receptor 期刊论文  OAI收割 ANALYTICAL CHEMISTRY, 2019, 卷号: 91, 期号: 13, 页码: 8162-8169 作者:  Lu, Yan;  Qin, Shanshan;  Zhang, Bingjie   |  收藏  |  浏览/下载：33/0  |  提交时间：2020/07/01 Efficient ligand discovery from natural herbs by integrating virtual screening, affinity mass spectrometry and targeted metabolomics 期刊论文  OAI收割 ANALYST, 2019, 卷号: 144, 期号: 9, 页码: 2881-2890 作者:  Wang, Zhihua;  Liang, Hao;  Cao, Haijie;  Zhang, Bingjie;  Li, Jun   |  收藏  |  浏览/下载：41/0  |  提交时间：2020/07/01