中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [42]
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期刊论文 [63]
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Identification of the VP37 pocket of monkeypox virus as a promising target for pan-orthopoxvirus inhibitors through virtual screening and antiviral assays
期刊论文
OAI收割
EMERGING MICROBES & INFECTIONS, 2024, 卷号: 13, 期号: 1, 页码: 4
作者:
Huo, Shuting
;
Wu, Leyun
;
Huang, Baoying
;
Liu, Nan
;
Sun, Jiewei
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/08/22
Design, synthesis, and biological evaluation of novel 1-amido-2-one-4-thio-deoxypyranose as potential antitumor agents for multiple myeloma
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 111, 页码: 16
作者:
Li, Xiaomei
;
Zhang, Hui
;
Dong, Sanfeng
;
Gao, Xuejie
;
Sun, Haiguo
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/09/26
Multiple myeloma
1-amido-2-one-4-thio-deoxypyranose
TRIP13 inhibitor
In vivo activity
MRFTrans: Multimodal Representation Fusion Transformer for Monocular 3D Semantic Scene Completion
期刊论文
OAI收割
Information Fusion, 2024, 页码: 102493
作者:
Xu RT(许镕涛)
;
Jiguang Zhang
;
Jiaxi Sun
;
Changwei Wang
;
Yifan Wu
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/06/24
Direct esterification of amides by the dimethylsulfate-mediated activation of amide C-N bonds
期刊论文
OAI收割
COMMUNICATIONS CHEMISTRY, 2024, 卷号: 7, 期号: 1, 页码: 9
作者:
Qin, Hongjian
;
Han, Zijian
;
Bonku, Emmanuel Mintah
;
Sun, Haiguo
;
Odilov, Abdullajon
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/05/31
D3EGFR: a webserver for deep learning-guided drug sensitivity prediction and drug response information retrieval for EGFR mutation-driven lung cancer
期刊论文
OAI收割
BRIEFINGS IN BIOINFORMATICS, 2024, 卷号: 25, 期号: 3, 页码: 10
作者:
Shi, Yulong
;
Li, Chongwu
;
Zhang, Xinben
;
Peng, Cheng
;
Sun, Peng
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2024/05/07
lung cancer
EGFR mutation
drug sensitivity prediction
patient case database
deep learning
Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity
in
vitro
and
in
vivo
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 98, 页码: 7
作者:
Dong, Sanfeng
;
Hu, Ke
;
Shi, Yulong
;
Wang, Guanli
;
Yu, Dandan
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/02/19
Multiple myeloma
TRIP13 inhibitor
Cantharidin
DCZ5418
DCZ0415
Discovery of seven-membered ring berberine analogues as highly potent and specific hCES2A inhibitors
期刊论文
OAI收割
CHEMICO-BIOLOGICAL INTERACTIONS, 2023, 卷号: 378, 页码: 11
作者:
Yang, Yun
;
Xiong, Yuan
;
Zhu, Guanghao
;
Sun, Mengru
;
Zou, Kun
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2023/10/17
Human carboxylesterase 2 (hCES2A)
Berberine analogues
Structure -activity relationships (SAR)
Inhibition kinetics
Selectivity
Chemo- and Site-Selective Lysine Modification of Peptides and Proteins under Native Conditions Using the Water-Soluble Zolinium
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 14
作者:
Sun, Haiguo
;
Xi, Mengyu
;
Jin, Qiang
;
Zhu, Zhengdan
;
Zhang, Yani
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/09/30
CoVac501, a self-adjuvanting peptide vaccine conjugated with TLR7 agonists, against SARS-CoV-2 induces protective immunity
期刊论文
OAI收割
CELL DISCOVERY, 2022, 卷号: 8, 期号: 1, 页码: 16
作者:
Long, Yiru
;
Sun, Jianhua
;
Song, Tian-Zhang
;
Liu, Tingting
;
Tang, Feng
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2022/06/15
Discovery of chiral N-2 '-aryletheryl-1 '-alkoxy-ethyl substituted arylisoquinolones with anti-inflammatory activity from the nucleophilic addition reactions of the thiophenols and oxazolinium
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 11
作者:
Li, Bo
;
Li, Heng
;
Zhu, Zhengdan
;
Xiang, Caigui
;
Xu, Zhijian
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2021/11/04
Anti-inflammatory activity
TNF alpha
ER beta
IBD Arylisoquinolones