中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [32]
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期刊论文 [173]
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Design, synthesis, and structure-activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 282, 页码: 21
作者:
Sui, Qibang
;
Zhou, Yuanyang
;
Li, Manjia
;
Wang, Dan
;
Cui, Rongrong
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/12/25
Synthetic lethal
MSI tumors
WRN inhibitors
Triazolo-pyrimidine derivatives
Reduced resting-state functional connectivity of default mode network subsystems in patients with obsessive-compulsive disorder
期刊论文
OAI收割
JOURNAL OF AFFECTIVE DISORDERS, 2025, 卷号: 369, 页码: 1108-1114
作者:
Guo, Qihui
;
Zhu, Rongrong
;
Zhou, Huixia
;
Ma, Zheng
;
He, Ying
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/12/09
Resting-state functional connectivity
Default mode network subsystems
Obsessive-compulsive disorder
Medication
Engineered IscB-WRNA system with improved base editing efficiency for disease correction via single AAV delivery in mice
期刊论文
OAI收割
CELL REPORTS, 2024, 卷号: 43, 期号: 11, 页码: 18
作者:
Guo, Ruochen
;
Sun, Xiaozhi
;
Wang, Feizuo
;
Han, Dingyi
;
Yang, Qiaoxia
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/12/16
Exploring the factors influencing the carbon sink function of coastal wetlands in the Yellow River Delta
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2024, 卷号: 14, 期号: 1, 页码: 15
作者:
Tang, Zhixiong
;
Wang, De
;
Tian, Xinpeng
;
Bi, Xiaoli
;
Zhou, Zixiang
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/01/10
Coastal wetlands
Soil organic carbon
Vegetation carbon sequestration
Influencing factor
Yellow River Delta
Exploring the factors influencing the carbon sink function of coastal wetlands in the Yellow River Delta
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2024, 卷号: 14, 期号: 1, 页码: 15
作者:
Tang, Zhixiong
;
Wang, De
;
Tian, Xinpeng
;
Bi, Xiaoli
;
Zhou, Zixiang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/01/10
Coastal wetlands
Soil organic carbon
Vegetation carbon sequestration
Influencing factor
Yellow River Delta
Synergism of salvianolic acid B and ginsenoside Rg1 magnifies the therapeutic potency against ischemic stroke
期刊论文
OAI收割
NEUROREPORT, 2024, 卷号: 35, 期号: 16, 页码: 1041-1051
作者:
Shen, Haishang
;
Zhang, Yuhan
;
Shao, Yanan
;
Chen, Siqi
;
Yin, Ping
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/11/26
Bliss independence statistical model
ginsenoside Rg1
glycerophospholipid metabolism
ischemic stroke
salvianolic acid B
synergistic effect
Arctic Amplification of marine heatwaves under global warming
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 9
作者:
He, Yan
;
Shu, Qi
;
Wang, Qiang
;
Song, Zhenya
;
Zhang, Min
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/12/20
NIR-II Responsive Fe-Doped Carbon Nanoparticles for Photothermal-Enhanced Chemodynamic Synergistic Oncotherapy
期刊论文
OAI收割
ACS APPLIED MATERIALS & INTERFACES, 2024, 卷号: 16
作者:
Wang, Xingyu
;
Song, Tianwei
;
Wu, Xianli
;
Lin, Yefeng
;
Shi, Xinyi
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/11/20
Fe doping
carbon nanoparticles
NIR-II response
photothermaltherapy
chemodynamic therapy
Endoplasmic reticulum-targeted delivery of celastrol and PD-L1 siRNA for reinforcing immunogenic cell death and potentiating cancer immunotherapy
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 8, 页码: 3643-3660
作者:
Wang, Jie
;
Zhang, Zilong
;
Zhuo, Yan
;
Zhang, Zhuan
;
Chen, Rongrong
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/09/26
Chemoimmunotherapy
Targeted drug delivery
Endoplasmic reticulum
Endoplasmic reticulum stress
Immunogenic cell death
siRNA
Exosomes
Colorectal cancer
Berberine attenuates 5-fluorouracil-induced intestinal mucosal injury by modulating the gut microbiota without compromising its anti-tumor efficacy
期刊论文
OAI收割
HELIYON, 2024, 卷号: 10
作者:
Wu, Changhong
;
Yang, Jie
;
Ye, Chenxiao
;
Wu, Hui
;
Shu, Wenxi
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/11/22
5-Fluorouracil
Berberine
Intestinal mucositis
PI3K/AKT/mTOR pathway
Intestinal flora