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Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共38条，第1-10条 帮助

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IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response 期刊论文  OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2025, 卷号: 14, 期号: 1, 页码: 19
作者:  Yao, Mingyue;  Yan, Wenzhong;  Wang, Yafang;  Zhao, Yu;  Xu, Xiaowei
  |  收藏  |  浏览/下载：5/0  |  提交时间：2025/04/01
Targeted Degradation of SOS1 Exhibits Potent Anticancer Activity and Overcomes Resistance in KRAS-Mutant Tumors and BCR-ABL-Positive Leukemia 期刊论文  OAI收割
CANCER RESEARCH, 2025, 卷号: 85, 期号: 1, 页码: 101-117
作者:  Luo, Ziwei;  Lin, Chencen;  Yu, Chuwei;  Yuan, Changxian;  Wu, Wenyong
  |  收藏  |  浏览/下载：11/0  |  提交时间：2025/02/28
Mutation in CDC42 Gene Set as a Response Biomarker for Immune Checkpoint Inhibitor Therapy 期刊论文  OAI收割
CANCER MEDICINE, 2025, 卷号: 14, 期号: 1, 页码: 13
作者:  Wang, Kun;  Zhang, Yingying;  Su, Zhaoming;  Wang, Bei;  Zhou, Yuanyang
  |  收藏  |  浏览/下载：6/0  |  提交时间：2025/04/01
Unraveling the CDK9/PP2A/ERK Network in Transcriptional Pause Release and Complement Activation in KRAS-mutant Cancers 期刊论文  OAI收割
ADVANCED SCIENCE, 2024, 页码: 20
作者:  Wang, Yafang;  Xu, Lansong;  Ling, Lijun;  Yao, Mingyue;  Shi, Shangxuan
  |  收藏  |  浏览/下载：17/0  |  提交时间：2024/10/21
Targeting ST8SIA6-AS1 counteracts KRASG12C inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling 期刊论文  OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 卷号: 12, 期号: 1, 页码: 22
作者:  Wang, Yafang;  Yao, Mingyue;  Li, Cheng;  Yang, Kexin;  Qin, Xiaolong
  |  收藏  |  浏览/下载：25/0  |  提交时间：2024/01/26
Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15
作者:  Mei, Lianghe;  Xu, Lansong;  Wu, Sanan;  Wang, Yafang;  Xu, Chao
  |  收藏  |  浏览/下载：60/0  |  提交时间：2023/10/17
Dual-acting antitumor agents targeting the A2A adenosine receptor and histone deacetylases: Design and synthesis of 4-(furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine derivatives 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 236, 页码: 114326
作者:  Zhang, Jinfeng;  Luo, Ziwei;  Duan, Wenwen
  |  收藏  |  浏览/下载：19/0  |  提交时间：2024/03/21
Structure-Based Design of Dual-Acting Compounds Targeting Adenosine A(2A) Receptor and Histone Deacetylase as Novel Tumor Immunotherapeutic Agents 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22, 页码: 16573-16597
作者:  Yan, Wenzhong;  Ling, Lijun;  Wu, Yiran;  Yang, Kexin;  Liu, Ruiquan
  |  收藏  |  浏览/下载：33/0  |  提交时间：2022/06/15
Preclinical characterization of SHR6390, a novel CDK 4/6 inhibitor, invitro and in human tumor xenograft models 期刊论文  OAI收割
CANCER SCIENCE, 2019, 卷号: 110, 期号: 4, 页码: 1420-1430
作者:  Long, Fei;  He, Ye;  Fu, Haoyu;  Li, Yun
  |  收藏  |  浏览/下载：38/0  |  提交时间：2020/07/01
Design, Synthesis and Pharmacological Evaluation of Novel Hsp90N-terminal Inhibitors Without Induction of Heat Shock Response 期刊论文  OAI收割
CHEMISTRYOPEN, 2019, 卷号: 8, 期号: 3, 页码: 344-353
作者:  Liu, Peng;  Chen, Xiangling;  Zhu, Jianming;  Li, Bo;  Chen, Zhaoqiang
  |  收藏  |  浏览/下载：52/0  |  提交时间：2020/07/01