机构

• 上海药物研究所 [10]
• 化学研究所 [3]
• 大连化学物理研究所 [2]
• 地球化学研究所 [2]
• 计算技术研究所 [1]
• 宁波材料技术与工程研... [1]
• 更多

采集方式

• OAI收割 [22]
• iSwitch采集 [1]

内容类型

• 期刊论文 [22]
• 会议论文 [1]

发表日期

• 2024 [1]
• 2023 [2]
• 2022 [3]
• 2021 [6]
• 2020 [1]
• 2019 [4]
• 更多

学科主题

筛选

浏览/检索结果: 共23条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 7, 页码: 5642-5661 作者:  Li, Yuan;  Xu, Tingting;  Zhao, Yue;  Zhang, Hui;  Liu, Zesheng   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/05/07 Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15 作者:  Kong, Linghui;  Ning, Kuan;  Liu, Xiao;  Lu, Jiashuo;  Chen, Baiyu   |  收藏  |  浏览/下载：40/0  |  提交时间：2023/10/17 N-cyclopropylmethyl nornepenthone derivatives  derivatives  Structure-activity relationship  MOR antagonist  Functional reversal  Reversal of subtype-selectivity  Opioid use disorder   Theory-guided doping of LaCoO3 nanoparticles for enhanced antimicrobial performance 期刊论文  OAI收割 Chemical Engineering Journal, 2023, 卷号: 464, 期号: 0, 页码: 142710 作者:  Junli Liu;  Kaitao Zhang;  Rongrong Shang;  Hua Zhang;  Jiahao Shen   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/11/29 SLL-627 Is a Highly Selective and Potent ? Opioid Receptor (KOR) Agonist with an Unexpected Nonreduction in Locomotor Activity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 16 作者:  Kong, Linghui;  Shu, Xuelian   |  收藏  |  浏览/下载：62/0  |  提交时间：2022/08/30 Discovery of 4-cyclopropyl-3-(2-((1-cyclopropyl-1H-pyrazol-4-yl) amino) quinazolin-6-yl)-N-(3-(trifluoromethyl) phenyl) benzamides as potent discoidin domain receptor inhibitors for the treatment of idiopathic pulmonary fibrosis 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 4, 页码: 1943-1962 作者:  Wang, Qi;  Tang, Bixi;  Sun, Dandan   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/08/16 Idiopathic pulmonary fibrosis  Discoidin domain receptor  Kinase  Inhibitor  Docking   Discovery of Pteridine-7(8H)-one Derivatives as Potent and Selective Inhibitors of Bruton's Tyrosine Kinase (BTK) 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 3, 页码: 2694-2709 作者:  Dou, Dou;  Diao, Yanyan;  Sha, Wenjie;  Su, Rongrong;  Tong, Linjiang   |  收藏  |  浏览/下载：42/0  |  提交时间：2022/08/16 Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433 作者:  He, Qian;  Wei, Yuanyuan;  Liu, Xiao;  Ye, Rongrong;  Kong, Linghui   |  收藏  |  浏览/下载：91/0  |  提交时间：2021/11/04 Guaianolide sesquiterpene lactones from Achillea millefolium L 期刊论文  OAI收割 PHYTOCHEMISTRY, 2021, 卷号: 186, 页码: 9 作者:  Li, Hongliang;  Li, Jun;  Liu, Mengqi;  Xie, Rongrong;  Zang, Yi   |  收藏  |  浏览/下载：38/0  |  提交时间：2021/06/11 Achillea millefolium L.  Asteraceae  Guaianolide sesquiterpene lactones  Millefoliumins A-G  Melaogenesis  Anti-inflammatory   Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging 期刊论文  OAI收割 ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030 作者:  Liu, Xiao;  Jiang, Shuang;  Kong, Linghui;  Ye, Rongrong;  Xiao, Li   |  收藏  |  浏览/下载：100/0  |  提交时间：2021/05/24 Morphinans  arylacetamidyl substituent  kappa opioid receptor modulators  structure-activity relationships   Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 期刊论文  OAI收割 AUTOPHAGY, 2021, 卷号: 17 作者:     |  收藏  |  浏览/下载：326/0  |  提交时间：2021/05/31 Autophagosome  cancer  flux  LC3  lysosome  macroautophagy  neurodegeneration  phagophore  stress  vacuole