机构

• 上海药物研究所 [16]

采集方式

• OAI收割 [16]

内容类型

• 期刊论文 [16]

发表日期

• 2025 [2]
• 2024 [1]
• 2023 [6]
• 2022 [2]
• 2021 [1]
• 2020 [4]
• 更多

学科主题

筛选

浏览/检索结果: 共16条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 De novo design of protein condensation inhibitors by targeting an allosteric site of cGAS 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 20 作者:     |  收藏  |  浏览/下载：4/0  |  提交时间：2025/08/20 Dynamic Cap-Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease 期刊论文  OAI收割 ADVANCED SCIENCE, 2025, 页码: 13 作者:  Su, Haixia;  Wu, Guoqing;  Xiong, Muya;  Wang, Yuhang;  Cao, Junyuan   |  收藏  |  浏览/下载：11/0  |  提交时间：2025/05/27 covalent inhibitors  I7L protease  monkeypox virus  protein structures  substrate proteolysis   Potency Prediction of Covalent Inhibitors against SARS-CoV-2 3CL-like Protease and Multiple Mutants by Multiscale Simulations 期刊论文  OAI收割 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2024, 卷号: 64, 期号: 24, 页码: 9501-9516 作者:  Xiong, Muya;  Nie, Tianqing;  Li, Zhewen;  Hu, Meiyi;  Su, Haixia   |  收藏  |  浏览/下载：18/0  |  提交时间：2025/01/06 Discovery of novel cGAS inhibitors based on natural flavonoids 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 14 作者:  Li, Jiameng;  Xiong, Muya;  Liu, Jiayuan;  Zhang, Fengping;  Li, Minjun   |  收藏  |  浏览/下载：35/0  |  提交时间：2023/12/08 Cyclic GMP-AMP synthase  Inhibitor  Flavonoids  Crystal structure  Virtual screening   Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15 作者:  Jiang, Xiangrui;  Su, Haixia;  Shang, Weijuan;  Zhou, Feng;  Zhang, Yan   |  收藏  |  浏览/下载：52/0  |  提交时间：2024/03/25 Multi-omics for COVID-19: driving development of therapeutics and vaccines 期刊论文  OAI收割 NATIONAL SCIENCE REVIEW, 2023, 卷号: 10, 期号: 9, 页码: 30 作者:  Guo, Mengyu;  Xiong, Muya;  Peng, Jinying;  Guan, Tong;  Su, Haixia   |  收藏  |  浏览/下载：23/0  |  提交时间：2023/12/19 COVID-19  SARS-CoV-2  multi-omics  antibodies  small-molecule drugs  vaccines   Discovery of Novel 5,6-Dihydro-1,2,4-triazine Derivatives as Efficacious Glucagon-Like Peptide-1 Receptor Agonists 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 23 作者:  Chen, Lili;  Yun, Ying;  Guo, Shimeng;  Wang, Xiaoyan;  Xiong, Muya   |  收藏  |  浏览/下载：35/0  |  提交时间：2023/10/17 Structure-Based Design of Potent Peptidomimetic Inhibitors Covalently Targeting SARS-CoV-2 Papain-like Protease 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 10, 页码: 15 作者:  Wang, Qian;  Chen, Guofeng;  He, Jian;  Li, Jiameng;  Xiong, Muya   |  收藏  |  浏览/下载：55/0  |  提交时间：2023/10/17 SARS-CoV-2  papain-like protease  covalent inhibitor  co-crystal structure  in vitro assay   Unraveling the catalytic mechanism of SARS-CoV-2 papain-like protease with allosteric modulation of C270 mutation using multiscale computational approaches 期刊论文  OAI收割 CHEMICAL SCIENCE, 2023, 卷号: 14, 期号: 18, 页码: 4681-4696 作者:  Shao, Qiang;  Xiong, Muya;  Li, Jiameng;  Hu, Hangchen;  Su, Haixia   |  收藏  |  浏览/下载：21/0  |  提交时间：2024/03/27 Bispecific prodrug nanoparticles circumventing multiple immune resistance mechanisms for promoting cancer immunotherapy 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 6, 页码: 2695-2709 作者:  Ye, Jiayi;  Hou, Bo;  Chen, Fangmin;  Zhang, Shunan;  Xiong, Muya   |  收藏  |  浏览/下载：43/0  |  提交时间：2024/03/21 Immunotherapy  Prodrug nanoparticles  Immune evasion  Immunogenic cell death  Tumor microenvironment