中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [11]
生态环境研究中心 [2]
地理科学与资源研究所 [1]
过程工程研究所 [1]
计算机网络信息中心 [1]
动物研究所 [1]
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期刊论文 [17]
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2025 [2]
2024 [4]
2023 [4]
2022 [4]
2018 [1]
2017 [1]
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A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in
KRAS
-driven cancers
期刊论文
OAI收割
CANCER CELL, 2025, 卷号: 43, 期号: 10, 页码: 32
作者:
Feng, Juanjuan
;
Xiao, Xuanzheng
;
Xia, Xinting
;
Min, Jian
;
Tang, Weiying
  |  
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  |  
Recent advances in targeted degradation in the RAS pathway
期刊论文
OAI收割
FUTURE MEDICINAL CHEMISTRY, 2025, 卷号: 17, 期号: 6, 页码: 693-708
作者:
Ge, Zhiming
;
Fan, Zisheng
;
He, Wei
;
Zhou, Guizhen
;
Zhou, Yidi
  |  
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  |  
Ginkgetin Alleviates Inflammation and Senescence by Targeting STING
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 15
作者:
Liu, Yadan
;
Ye, Jialin
;
Fan, Zisheng
;
Wu, Xiaolong
;
Zhang, Yinghui
  |  
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  |  
An updated patent review of SOS1 inhibitors (2022-present)
期刊论文
OAI收割
EXPERT OPINION ON THERAPEUTIC PATENTS, 2024, 页码: 15
作者:
Zhou, Guizhen
;
Zhou, Chuan
;
Ma, Xinyi
;
Xu, Jiahang
;
Zhou, Zehui
  |  
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  |  
Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido [2,3-
d
]pyrimidin-7-one-based SOS1 inhibitor
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 107, 页码: 9
作者:
Wang, Kun
;
Zhou, Zehui
;
Ma, Xinyi
;
Xu, Jiahang
;
Xu, Wangyang
  |  
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  |  
Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRAS
G12D
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167
作者:
Zhou, Chuan
;
Fan, Zisheng
;
Gu, Yuejiao
;
Ge, Zhiming
;
Tao, Zhaofan
  |  
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  |  
Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 6, 页码: 4197-4214
作者:
Zhou, Zehui
;
Zhou, Guizhen
;
Zhou, Chuan
;
Fan, Zisheng
;
Cui, Rongrong
  |  
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  |  
Design, Synthesis, and Biological Evaluation of Bipyridazine Derivatives as Stimulator of Interferon Genes (STING) Receptor Agonists
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 5, 页码: 3327-3347
作者:
Shan, Bin
;
Hou, Hui
;
Zhang, Keke
;
Li, Rui
;
Shen, Chang
  |  
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  |  
Carbon flow through continental-scale ground logistics transportation
期刊论文
OAI收割
ISCIENCE, 2023, 卷号: 26, 期号: 1, 页码: 105792
作者:
Cui, Haotian
;
Lu, Yonglong
;
Zhou, Yunqiao
;
He, Guizhen
;
Song, Shuai
  |  
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  |  
Design, Synthesis, and Bioevaluation of Pyrido[2,3-d]pyrimidin-7-ones as Potent SOS1 Inhibitors
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2023, 页码: 183-190
作者:
Liu, Meiying
;
Zhou, Guizhen
;
Su, Wenhong
;
Gu, Yuejiao
;
Gao, Mingshan
  |  
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  |