中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
自动化研究所 [4]
广州地球化学研究所 [2]
宁波材料技术与工程研... [2]
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OAI收割 [21]
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期刊论文 [18]
会议论文 [3]
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2025 [1]
2024 [2]
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Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22
作者:
Guma, Samuel Desta
;
Zhou, Zhaoyin
;
Song, Kang
;
Yang, Feipu
;
Suo, Jin
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/12/11
SARS-CoV-2
3CL pro inhibitors
Peptidomimetics
Spiropyrrolidine derivatives
F-CPI: A Multimodal Deep Learning Approach for Predicting Compound Bioactivity Changes Induced by Fluorine Substitution
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 13
作者:
Zhang, Qian
;
Yin, Wenhai
;
Chen, Xinyao
;
Zhou, Aimin
;
Zhang, Guixu
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/02/28
Discovery of the potent covalent inhibitor with an acrylate warhead for SARS-CoV-2 3CL protease
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 112, 页码: 5
作者:
Shen, Wen
;
Chen, Xinyao
;
Zhou, Liping
;
Cheng, Yan
;
Zhang, Yan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/10/21
COVID-19
SARS-CoV-2 3CL pro inhibitor
Drug design
Antiviral activities
Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15
作者:
Jiang, Xiangrui
;
Su, Haixia
;
Shang, Weijuan
;
Zhou, Feng
;
Zhang, Yan
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2024/03/25
Tracing the origin and formation mechanisms of coalbed gas from the Fuxin Basin in China using geochemical and isotopic signatures of the gas and coproduced water
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF COAL GEOLOGY, 2023, 卷号: 267, 页码: 12
作者:
Chen, Xiangrui
;
Wang, Yunpeng
;
Tao, Mingxin
;
Zhou, Zheng
;
He, Zhihua
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/08/22
Microbial coalbed gas
Coproduction water
CO 2 dissolution
Isotope fractionation
Fuxin Basin
Geological control on carbon isotope equilibrium and kinetic fractionation of CH4-CO2-HCO3 in microbial coalbed and shale gas systems
期刊论文
OAI收割
CHEMICAL GEOLOGY, 2023, 卷号: 635, 页码: 121609
作者:
Chen, Xiangrui
;
Tao, Mingxin
;
Zhou, Zheng
;
Holland, Greg
;
Wang, Yunpeng
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2024/09/26
DISSOLVED INORGANIC CARBON
SAN-JUAN BASIN
PRODUCTION WATERS
BIOGENIC METHANE
IN-SITU
HYDROGEN
SOLUBILITY
EXCHANGE
BED
CO2
Molecular recognition of morphine and fentanyl by the human mu-opioid receptor
期刊论文
OAI收割
CELL, 2022, 卷号: 185, 期号: 23, 页码: 4361-+
作者:
Zhuang, Youwen
;
Wang, Yue
;
He, Bingqing
;
He, Xinheng
;
Zhou, X. Edward
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收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/04/10
Prodrug nanoparticles rationally integrating stroma modification and chemotherapy to treat metastatic pancreatic cancer
期刊论文
OAI收割
BIOMATERIALS, 2021, 卷号: 278
作者:
Wang, Liying
;
Liu, Zimo
;
Zhou, Quan
;
Gu, Sufang
;
Liu, Xiangsheng
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2021/11/29
Pancreatic cancer
Polymeric prodrug
Calcipotriol
Cancer-associated fibroblast
Metastasis
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target
期刊论文
OAI收割
CELL RESEARCH, 2021, 页码: 14
作者:
Xia, Bingqing
;
Shen, Xurui
;
He, Yang
;
Pan, Xiaoyan
;
Liu, Feng-Liang
  |  
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2021/08/17
Structural limiting factors of mixed-valent tin oxides in photoelectrochemical application: A comparative exploration
期刊论文
OAI收割
JOURNAL OF ENERGY CHEMISTRY, 2021, 卷号: 56, 页码: 504-511
作者:
Zou, Yalong
;
Liu, Deyu
;
Meng, Xiangrui
;
Liu, Qitao
;
Zhou, Yang
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/12/01