中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [13]
广州地球化学研究所 [2]
地理科学与资源研究所 [1]
采集方式
OAI收割 [16]
内容类型
期刊论文 [16]
发表日期
2024 [2]
2023 [3]
2022 [1]
2021 [2]
2020 [3]
2018 [1]
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学科主题
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Submicron Organic Aerosol Types in the Summertime Arctic: Mixing State, Geographic Distribution, and Drivers
期刊论文
OAI收割
JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 2024, 卷号: 129, 期号: 17, 页码: 14
作者:
Su, Bojiang
;
Zhang, Guohua
;
Song, Congbo
;
Liang, Yue
;
Wang, Longqun
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
individual organic aerosol particles
mixing state
summertime high Arctic
geographic distribution
driver
machine learning
Ecto-nucleotide pyrophosphatase/phosphodiesterase 1 inhibitors: Research progress and prospects
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 267, 页码: 13
作者:
Guan, Dezhong
;
Fang, Lincheng
;
Feng, Mingshun
;
Guo, Shi
;
Xie, Lingfeng
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/05/07
ENPP1 inhibitors
cGAS-STING pathway
2 ', 3 '-cGAMP
Tumor immunotherapy
Enrichment of calcium in sea spray aerosol: insights from bulk measurements and individual particle analysis during the R/V
Xuelong
cruise in the summertime in Ross Sea, Antarctica
期刊论文
OAI收割
ATMOSPHERIC CHEMISTRY AND PHYSICS, 2023, 卷号: 23, 期号: 18, 页码: 10697-10711
作者:
Su, Bojiang
;
Bi, Xinhui
;
Zhang, Zhou
;
Liang, Yue
;
Song, Congbo
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/09/12
Design, synthesis and pharmacological evaluation of 2,3-dihydrobenzo-furan IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 16
作者:
Chen, Yun
;
Ning, Yi
;
Chen, Zhiwei
;
Xue, Yaping
;
Wu, Qingyun
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/10/17
Apoptosis
Diffuse large B-Cell lymphoma
Interleukin-1 receptor associated kinase 4
Structure-based drug design
2
3-Dihydrobenzofuran
Design, synthesis and biological evaluation of KRASG12C-PROTACs
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 78, 页码: 14
作者:
Zhang, Xiaoyi
;
Zhao, Tong
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2023/04/10
KRASG12C
PROTAC
Covalent inhibitors
Structure-activity relationships (SARs)
Anticancer
Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation
期刊论文
OAI收割
CELL DISCOVERY, 2022, 卷号: 8, 期号: 1, 页码: 17
作者:
Xie, Zuoquan
;
Wang, Zhen
;
Fan, Fengying
;
Zhou, Jinpei
;
Hu, Zhaoxue
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2023/04/10
Discovery and structure - activity relationship exploration of pyrazolo [1,5-a]pyrimidine derivatives as potent FLT3-ITD inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 48, 页码: 13
作者:
Chen, Yun
;
Bai, Gang
;
Li, Yan
;
Ning, Yi
;
Cao, Sufen
  |  
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2021/12/01
FLT3
FLT3-ITD
Acute myeloid leukemia
Structure-activity relationships
Pyrazolo[1, 5-a]pyrimidine
Design, Synthesis, and Biological Evaluation of IRAK4-Targeting PROTACs
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 1, 页码: 82-87
作者:
Chen, Yun
;
Ning, Yi
;
Bai, Gang
;
Tong, Linjiang
;
Zhang, Tao
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2021/05/24
IRAK4
PROTAC
protein degrader
scaffolding role
diffuse large B-cell lymphoma
DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation
期刊论文
OAI收割
BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69
作者:
Lv, Jianlu
;
Wang, Wei
;
Zhu, Xialin
;
Xu, Xiaoju
;
Yan, Qiuying
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/12/21
Alzheimer'sdisease
Microglia
AMPK alpha 1
DW14006
Phagocytosis
Neuro-inflammation
DW14006 as a Direct AMPK alpha Activator Ameliorates Diabetic Peripheral Neuropathy in Mice
期刊论文
OAI收割
DIABETES, 2020, 卷号: 69, 期号: 9, 页码: 1974-1988
作者:
Xu, Xu
;
Wang, Wei
;
Wang, Zhengyu
;
Lv, Jianlu
;
Xu, Xiaoju
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/12/24