中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [28]
海洋研究所 [4]
西北高原生物研究所 [3]
上海营养与健康研究所 [2]
沈阳应用生态研究所 [2]
合肥物质科学研究院 [2]
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OAI收割 [48]
iSwitch采集 [2]
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期刊论文 [46]
会议论文 [2]
学位论文 [2]
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2022 [2]
2020 [1]
2019 [2]
2018 [5]
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Cardiovasc... [2]
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Multiple-dose up-titration study to evaluate the pharmacokinetics, safety and antitumor activity of apatinib in advanced gastric adenocarcinoma
期刊论文
OAI收割
FRONTIERS IN ONCOLOGY, 2022, 卷号: 12, 页码: 10
作者:
Wang, Yonggang
;
Wang, Chang
;
Zhang, Yanqiao
;
Hao, Jiqing
;
Yang, Nong
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/12/13
apatinib
angiogenesis
gastric adenocarcinoma
pharmacokinetics
VEGFR
VEGFR-2
Design and semisynthesis of oleanolic acid derivatives as VEGF in- hibitors: Inhibition of VEGF-induced proliferation, angiogenesis, and VEGFR2 activation in HUVECs
期刊论文
OAI收割
CHINESE JOURNAL OF NATURAL MEDICINES, 2022, 卷号: 20, 期号: 3, 页码: 229-240
作者:
Meng Ning
;
Xie Hong-Xu
;
Hou Jia-Rong
;
Chen Yon-Bin
;
Wu Meng-Jun
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/06/15
Oleanolic acid
Structural modification
VEGF inhibitor
VEGFR2
Angiogenesis
Discovery of a highly selective VEGFR2 kinase inhibitor CHMFL-VEGFR2-002 as a novel anti-angiogenesis agent
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10
作者:
Jiang, Zongru
;
Wang, Li
;
Liu, Xuesong
;
Chen, Cheng
;
Wang, Beilei
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2020/11/26
Cancer
VEGFR2 kinase
Kinase inhibitor
Angiogenesis
Inhibitor selectivity
Exploring binding mechanisms of VEGFR2 with three drugs lenvatinib, sorafenib, and sunitinib by molecular dynamics simulation and free energy calculation
期刊论文
OAI收割
CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 93, 期号: 5, 页码: 934-948
作者:
Wang, Yu
;
Peng, Cheng
;
Wang, Guimin
;
Xu, Zhijian
;
Luo, Yongfeng
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
hydrophobic contact scanning
MM
GBSA
molecular dynamics simulation
VEGFR2-drugs interaction
TAF1 plays a critical role in AML1-ETO driven leukemogenesis
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2019, 卷号: 10, 期号: -, 页码: 4925
作者:
Xu, Ye
;
Man, Na
;
Karl, Daniel
;
Martinez, Concepcion
;
Liu, Fan
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/12/09
Osteoglycin
Angiogenesis
Extracellular matrix
VEGF
VEGFR2
Design, synthesis and biological evaluation of a series of novel 2-benzamide-4-(6-oxy-N-methyl-l-naphthamide)-pyridine derivatives as potent fibroblast growth factor receptor (FGFR) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 154, 页码: 9-28
作者:
Wei, Manman
;
Peng, Xia
;
Xing, Li
;
Dai, Yang
;
Huang, Ruimin
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2019/01/08
FGFR
VEGFR
Synergistic effect
Tumor growth inhibition
Lucitanib
PBA2 exhibits potent anti-tumor activity via suppression of VEGFR2 mediated-cell proliferation and angiogenesis
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 150, 页码: 131-140
作者:
Fang, Xiaona
;
Xie, Hua
;
Luo, Min
;
Chen, Zhen
;
Wang, Fang
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2019/01/08
Angiogenesis
And-tumor activity
Multi-tyrosine kinases inhibitor
PBA2
VEGFR2
Preclinical characterization of anlotinib, a highly potent and selective vascular endothelial growth factor receptor-2 inhibitor
期刊论文
OAI收割
CANCER SCIENCE, 2018, 卷号: 109, 期号: 4, 页码: 1207-1219
作者:
Xie, Chengying
;
Wan, Xiaozhe
;
Quan, Haitian
;
Zheng, Mingyue
;
Fu, Li
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/01/08
angiogenesis
anlotinib
tyrosine kinase inhibitor
VEGF
VEGFR2
Ph-triggered peptide self-assembly for targeting imaging and therapy toward angiogenesis with enhanced signals
期刊论文
iSwitch采集
Acs applied materials & interfaces, 2018, 卷号: 10, 期号: 9, 页码: 7871-7881
作者:
Qian, Yixia
;
Wang, Weizhi
;
Wang, Zihua
;
Jia, Xiangqian
;
Han, Qiuju
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/04/23
Ph-triggered
Vegfr2
Self-assembly
Biaimaging
Cancer therapy
Chamaejasmine B Induces the Anergy of Vascular Endothelial Cells to VEGFA Pro-angiogenic Signal by Autophagic Regulation of VEGFR2 in Breast Cancer
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 8
作者:
Li, Qi
;
Kan, Xiaoxi
;
Yin, Jie
;
Sun, Lidong
;
Wang, Yajie
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2019/06/20
Chamaejasmine b
Anti-angiogenesis Chemotherapy
Breast Cancer
Autophagy
Vegfr2