机构

• 上海药物研究所 [19]
• 心理研究所 [8]
• 昆明植物研究所 [8]
• 昆明动物研究所 [5]
• 西北高原生物研究所 [3]
• 兰州化学物理研究所 [2]
• 更多

采集方式

• OAI收割 [48]

内容类型

• 期刊论文 [46]
• 学位论文 [2]

发表日期

• 2025 [3]
• 2022 [4]
• 2021 [5]
• 2020 [5]
• 2019 [4]
• 2018 [3]
• 更多

学科主题

• Biochemist... [1]
• Biochemist... [1]
• Chemistry [1]
• Pharmacolo... [1]
• 生物学 [1]
• 行为遗传学 [1]
• 更多

筛选

浏览/检索结果: 共48条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择作者升序作者降序发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序 Conformational restriction enables discovering a series of chroman derivatives as potent and selective NaV1.8 inhibitors with improved pharmacokinetic properties 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 293, 页码: 24 作者:  Li, Na;  Wang, Linlin;  Hu, Xinyuan;  Xu, Haiyan;  Yang, Bowen   |  收藏  |  浏览/下载：20/0  |  提交时间：2025/08/20 Voltage-gated sodium channel 1.8  Conformational restriction  Pharmacokinetic  Structure-activity relationship  Analgesic   Dezocine Exerts Analgesic Effects in Chronic Pain by Activation of κ- and μ-Opioid Receptors and Inhibition of Norepinephrine and Serotonin Reuptake 期刊论文  OAI收割 PAIN RESEARCH & MANAGEMENT, 2025, 卷号: 2025, 期号: 1, 页码: 9 作者:  Liu, Zihan;  Liu, Anan;  Chen, Jing;  Chai, Jing-Rui;  Liu, Panwen   |  收藏  |  浏览/下载：26/0  |  提交时间：2025/05/27 analgesic  chronic pain  dezocine  norepinephrine reuptake  opioid receptor  serotonin reuptake   Network Pharmacology and Molecular Dynamics Simulations Reveal the Mechanism of Total Alkaloid Components in Anisodus Tanguticus (Maxim.) Pascher in Treating Inflammation and Pain 期刊论文  OAI收割 CHEMISTRY & BIODIVERSITY, 2025, 卷号: 22, 期号: 1 作者:  Tan, Nixia;  Wang, Yue;  Ren, Lichengcheng;  Tie, Fangfang;  Hu, Na   |  收藏  |  浏览/下载：10/0  |  提交时间：2025/11/27 Anisodus tanguticus (Maxim.) Pascher  Network pharmacology  Molecular dynamics simulations  Anti-inflammatory and analgesic effects  Mechanism of action   Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106493 作者:  Munikishore,Rachakunta;  Liu,Rui;  Zhang,Shuqun;  Zhao,Qin-Shi;  Nian,Yin   |  收藏  |  浏览/下载：54/0  |  提交时间：2024/07/22 Buxus alkaloid  Structural modification  T -type calcium channel  Analgesic activity  Docking analysis  Structure -activity relationship study  BUXOZINE-C  SEMPERVIRENS  RING  CONSTITUTION   The Effect of Tramadol Versus Sufentanil on Controlling Postoperative Pain for Men Who Smoke and Do Not Smoke: A Randomized Clinical Trial 期刊论文  OAI收割 PAIN PHYSICIAN, 2022, 卷号: 25, 期号: 9, 页码: E1367-E1377 作者:  Wei, Kai;  Bi, Yanzhi;  Xu, Huihong;  Shen, Ling;  Liu, Yantao   |  收藏  |  浏览/下载：47/0  |  提交时间：2023/03/13 Men patients who smoke  tramadol  sufentanil  postoperative pain management  analgesic efficacy  RCT  analgesic consumption  partial hepatectomy   (-)-Naringenin 4 ',7-dimethyl Ether Isolated from Nardostachys jatamansi Relieves Pain through Inhibition of Multiple Channels 期刊论文  OAI收割 MOLECULES, 2022, 卷号: 27, 期号: 5, 页码: 17 作者:  Gu, Ru-Rong;  Meng, Xian-Hua;  Zhang, Yin;  Xu, Hai-Yan;  Zhan, Li   |  收藏  |  浏览/下载：59/0  |  提交时间：2022/06/15 (-)-Naringenin 4 ',7-dimethyl ether  analgesic candidate  mechanism study  delayed rectifier potassium currents  ion channels   Cyclovirobuxine D, a cardiovascular drug from traditional Chinese medicine, alleviates inflammatory and neuropathic pain mainly via inhibition of voltage-gated Ca(v)3.2 channels 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 1081697 作者:  Su, Deyuan;  Gong, Ye;  Li, Songyu;  Yang, Jian;  Nian, Yin   |  收藏  |  浏览/下载：27/0  |  提交时间：2024/08/21 Cyclovirobuxine D  Ca(v)3  2  Ca(v)2  Buxus microphylla  analgesic effects  ROOT GANGLION NEURONS  CALCIUM-CHANNELS  CELL-PROLIFERATION  PACLITAXEL  RAT  RECEPTOR  GENE  EXPRESSION  APOPTOSIS  CURRENTS   (-)-Naringenin 4’,7-Dimethyl Ether Isolated from Nardostachys jatamansi Relieves Pain Through Inhibition of Multiple Channels 期刊论文  OAI收割 Molecules, 2022, 卷号: 5, 期号: 27, 页码: 1735 作者:  Ru-Rong Gu;  Xian-Hua Meng;  Yin Zhang;  Hai-Yan Xu;  Li Zhan   |  收藏  |  浏览/下载：58/0  |  提交时间：2022/11/30 (-)-Naringenin 40,7-dimethyl ether  analgesic candidate  mechanism study  delayed rectifier potassium currents  ion channels   Quantitative Electrophysiological Evaluation of the Analgesic Efficacy of Two Lappaconitine Derivatives: A Window into Antinociceptive Drug Mechanisms 期刊论文  OAI收割 NEUROSCIENCE BULLETIN, 2021, 页码: 15 作者:  Teng, Guixiang;  Zhang, Fengrui;  Li, Zhenjiang;  Zhang, Chun;  Zhang, Libo   |  收藏  |  浏览/下载：76/0  |  提交时间：2021/10/29 Electrocorticogram  Analgesic effect  Lappaconitine derivatives  Antinociceptive mechanisms  Laser-evoked potentials   Current Understanding of the Involvement of the Insular Cortex in Neuropathic Pain: A Narrative Review 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 5, 页码: 16 作者:  Wang, Ning;  Zhang, Yu-Han;  Wang, Jin-Yan;  Luo, Fei   |  收藏  |  浏览/下载：93/0  |  提交时间：2021/04/30 neuropathic pain  insular cortex  analgesic response  receptor  sex differences