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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [11]
金属研究所 [1]
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上海生物化学与细胞生... [1]
生态环境研究中心 [1]
长春应用化学研究所 [1]
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OAI收割 [16]
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期刊论文 [15]
会议论文 [1]
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2022 [1]
2021 [2]
2020 [1]
2018 [1]
2016 [2]
2015 [4]
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The Effect of Tramadol Versus Sufentanil on Controlling Postoperative Pain for Men Who Smoke and Do Not Smoke: A Randomized Clinical Trial
期刊论文
OAI收割
PAIN PHYSICIAN, 2022, 卷号: 25, 期号: 9, 页码: E1367-E1377
作者:
Wei, Kai
;
Bi, Yanzhi
;
Xu, Huihong
;
Shen, Ling
;
Liu, Yantao
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/03/13
Men patients who smoke
tramadol
sufentanil
postoperative pain management
analgesic efficacy
RCT
analgesic consumption
partial hepatectomy
Discovery, Structure-Activity Relationship, and Mechanistic Studies of 1-((3R,4S)-3-((Dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)-2-(2,4,5-trifluorophenyl)ethan-1-one as a Novel Potent Analgesic
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9458-9483
作者:
Huang, Huoming
;
Li, Xueping
;
Xie, Peng
;
Li, Xinwei
;
Xu, XueJun
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2021/08/17
Design, Synthesis, and Structure-Activity Relationship Exploration of Alkyl/Phenylalkyl Piperidine Analogues as Novel Highly Potent and Selective mu Opioid Receptor Agonists
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 2, 页码: 285-299
作者:
Huang, Huoming
;
Li, Xinwei
;
Guo, Wei
;
Zhu, Chen
;
Qian, Yuanyuan
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
pain
opioid analgesic
SAR
selective MOR agonist
molecular dynamics simulations
Discovery of 3-((dimethylamino)methyl)-4-hydroxy-4-(3-methoxypheny1)-N-phenylpiperidine-1-carboxamide as novel potent analgesic
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 189, 页码: 14
作者:
Huang, Huoming
;
Wang, Wenli
;
Xu, Xuejun
;
Zhu, Chen
;
Wang, Yujun
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Selective MOR agonists
Antinociception
Analgesic
Opioids
Molecular mechanism
Clinical opioids differentially induce co-internalization of mu- and delta-opioid receptors
期刊论文
OAI收割
MOLECULAR PAIN, 2018, 卷号: 14, 期号: 1, 页码: 1-15
作者:
Bao, Fenghua
;
Li, Chang-Lin
;
Lu, Ying-Jin
;
Zhang, Xu
;
Chen, Xu-Qiao
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/04/28
Protein-coupled Receptors
Knock-out Mice
Morphine Antinociceptive Tolerance
Dorsal-root Ganglia
Opiate Tolerance
Beta-arrestin
Desensitization
Trafficking
Dependence
Analgesia
Discovery of Potent and Selective Agonists of delta Opioid Receptor by Revisiting the "Message-Address" Concept
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 7, 期号: 4, 页码: 391-396
作者:
Shen, Qing
;
Qian, Yuanyuan
;
Huang, Xiaoqin
;
Xu, Xuejun
;
Li, Wei
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
delta opioid receptor
agonist
affinity
selectivity
molecular docking
A simple method for quantification of tapentadol in dog plasma by liquid chromatography-tandem mass spectrometry and evaluation of the effects of conjugated metabolites on tapentadol
期刊论文
OAI收割
Acta Pharmaceutica Sinica, 2016, 卷号: 51, 期号: 3, 页码: 434-438
作者:
Liang Ge
;
Lu Youming
;
Dai Xiaojian
;
Qin Minjian
;
Zhong Dafang
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
LC-MS/MS
LC-MS/MS
tapentadol
conjugated metabolite
pharmacokinetics
Chlorination of tramadol: Reaction kinetics, mechanism and genotoxicity evaluation
期刊论文
OAI收割
CHEMOSPHERE, 2015, 卷号: 141, 期号: 0, 页码: 282-289
作者:
Cheng, Hanyang
;
Song, Dean
;
Chang, Yangyang
;
Liu, Huijuan
;
Qu, Jiuhui
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2016/03/11
Chlorination
Tramadol
Kinetics
Pathway and mechanism
Genotoxicity
Design, synthesis and biological evaluation of N-phenylalkyl-substituted tramadol derivatives as novel mu opioid receptor ligands
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 7, 页码: 887-894
作者:
Shen, Qing
;
Qian, Yuan-yuan
;
Xu, Xue-jun
;
Li, Wei
;
Liu, Jing-gen
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
mu-opioid receptor
tramadol
morphine
molecular docking
designsynthesisandbiologicalevaluationofnphenylalkylsubstitutedtramadolderivativesasnovelopioidreceptorligands
期刊论文
OAI收割
actapharmacologicasinica, 2015, 卷号: 36, 期号: 7, 页码: 887
作者:
Shen Qing
;
Qian Yuanyuan
;
Xu Xuejun
;
Li Wei
;
Liu Jinggen
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
μ-opioid receptor
tramadol
morphine
molecular docking