中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [49]
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Chemical structure and anti-inflammatory effects on intestinal epithelial cells of a novel mannogalactan purified from
Typhonium
giganteum
Engl.
期刊论文
OAI收割
CARBOHYDRATE RESEARCH, 2025, 卷号: 552, 页码: 13
作者:
Luo, Hongchen
;
Lai, Zhengyang
;
Shi, Lexue
;
Hu, Yulong
;
Jin, Can
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/05/27
Typhonium giganteum Engl.
Polysaccharide
NCM460cells
Anti-inflammation
NF-kappa B
MAPK
Targeted inhibition of Gus-expressing Enterococcus faecalis to promote intestinal stem cell and epithelial renovation contributes to the relief of irinotecan chemotoxicity by dehydrodiisoeugenol
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 12, 页码: 5286-5304
作者:
Gao, Ruiyang
;
Yue, Bei
;
Lv, Cheng
;
Geng, Xiaolong
;
Yu, Zhilun
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/04/01
Irinotecan
Intestinal mucositis
b-Glucuronidase
Enterococcus faecalis
Intestinal stem cells
Epithelial regeneration
bacteria-host irinotecan axis
Dehydrodiisoeugenol
Acetaldehyde induces similar cytotoxic and genotoxic risks in BEAS-2B cells and HHSteCs: involvement of differential regulation of MAPK/ERK and PI3K/AKT pathways
期刊论文
OAI收割
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2023, 卷号: 30
作者:
Zhang, Jingni
;
Wang, Hongjuan
;
Chen, Huan
;
Liu, Yong
;
Wang, An
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2023/11/17
Acetaldehyde
Cytotoxicity
Genotoxicity
BEAS-2B cells
HHSteCs
MAPK/ERK
PI3K/AKT
Quassinoids from Twigs of Harrisonia perforata (Blanco) Merr and Their Anti-Parkinson's Disease Effect
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 22, 页码: 16196
作者:
Cai,Min
;
Bai,Xiao-Lin
;
Zang,Hao-Jing
;
Tang,Xiao-Han
;
Yan,Ying
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/05/09
Harrisonia perforata
quassinoid
simarubaceae
neuroprotection
PC12 cells
PINK1(B9) flies
PROMISING BIOLOGICAL-ACTIVITY
UNPRECEDENTED QUASSINOIDS
Rubiginosin B selectively inhibits Treg cell differentiation and enhances anti-tumor immune responses by targeting calcineurin-NFAT signaling pathway
期刊论文
OAI收割
PHYTOMEDICINE, 2023, 卷号: 116, 页码: 154898
作者:
Geng,Chang-An
;
Chen,Feng-Yang
;
Zheng,Jing-Bin
;
Liao,Ping
;
Li,Tian-Ze
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/07/17
Rubiginosin B (RGB)
CD4(+)Foxp3(+) regulatory T cells (Tregs)
Calcineurin
Nuclear factor of activated T cells (NFAT)
Tumor microenvironment
Rhododendron brachypodum
REGULATORY T-CELLS
RHODODENDRON
IMMUNOSUPPRESSION
DERIVATIVES
INDUCTION
EXPANSION
RAPAMYCIN
Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 210, 页码: 115491
作者:
Gou,Leilei
;
Yue,Grace Gar-Lee
;
Lee,Julia Kin -Ming
;
Puno,Pema Tenzin
;
Lau,Clara Bik-San
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/07/22
Breast cancer
Metastasis
Natural products
Eriocalyxin B
Cancer recurrence
Cancer stem cells
Gut microbiome
NF-KAPPA-B
STEM-CELLS
MOLECULAR-MECHANISMS
EXTRACELLULAR-MATRIX
TUMOR-GROWTH
APOPTOSIS
ANGIOGENESIS
PROGRESSION
CARCINOMA
LEUKEMIA
Guaiane-type Sesquiterpenoid Dimers from Artemisia zhongdianensis and Antihepatoma Carcinoma Activity via the p38MAPK Pathway
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2023, 卷号: 41, 期号: 19, 页码: 2453-2468
作者:
Dong,Wei
;
Ma,Wen-Jing
;
Ma,Yun-Bao
;
Li,Feng-Jiao
;
Li,Tian-Ze
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/07/10
Artemzhongdianolides B1-B17
Artemisia zhongdianensis
Guaiane-type sesquiterpenoid dimers
Antihepatoma activity
p38MAPK pathway
Cancer
NMR spectroscopy
X-ray diffraction
ARREST
CELLS
JNK
Different Immunoregulation Roles of Activin A Compared With TGF-beta
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2022, 卷号: 13, 页码: 9
作者:
Li, Fanglin
;
Long, Yiru
;
Yu, Xiaolu
;
Tong, Yongliang
;
Gong, Likun
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/08/16
activin A
TGF-beta
activin A signaling
macrophages
dendritic cells
B cells
T effector cells
regulatory T cells
Anti-Inflammatory Effects of Camellia fascicularis Polyphenols via Attenuation of NF-kappa B and MAPK Pathways in LPS-Induced THP-1 Macrophages
期刊论文
OAI收割
JOURNAL OF INFLAMMATION RESEARCH, 2022, 卷号: 15, 页码: 851-864
作者:
Gao, Miaozi
;
Peng, Xiaowei
;
Tang, Junrong
;
Deng, Jia
;
Wang, Fang
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/04/30
Camellia fascicularis
polyphenols
anti-inflammatory activity
NF-kappa B
MAPK
LIPOPOLYSACCHARIDE-INDUCED INFLAMMATION
OXIDATIVE STRESS
CELLS
SUPPRESSION
ANTIOXIDANT
ACTIVATION
NRF2/HO-1
RESPONSES
PROTEIN
CANCER
A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Liu, Yu-ting
;
Ding, Hui-hua
;
Lin, Ze-min
;
Wang, Que
;
Chen, Li
  |  
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2021/05/24
rheumatoid arthritis
BTK inhibitors
B cells
macrophages
RANKL
osteoclastogenesis