中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [19]
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期刊论文 [87]
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Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2025, 页码: 14
作者:
Wen, Yiming
;
Xu, Peijia
;
Chen, Yijie
;
Meng, Jingyi
;
Zheng, Mingyue
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
p53 Y220C
Covalent stabilizer
Virtual screening
Molecular dynamics
DNA binding
Structure-activity relationship
Cancer therapy
Rational design and discovery of novel oxalate-like derivatives as aphid-repellent candidates based on odorant-binding protein 3
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1301, 页码: 11
作者:
Zhu, Ziwei
;
Li, Jianing
;
Liu, Chong
;
Li, Huilin
;
Lu, Xingxing
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/04/09
Odorant-binding protein
Oxalate-like derivatives
Rational design
Repellent activity
Behavioural control agents
LysM-containing proteins function in the resistance of Litopenaeus vannamei against Vibrio parahaemolyticus infection
期刊论文
OAI收割
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2023, 卷号: 148, 页码: 9
作者:
Miao, Miao
;
Li, Shihao
;
Yu, Yang
;
Li, Fuhua
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/12/13
Lysin motif
Litopenaeus vannamei
Binding activity
V. parahaemolyticus
SNPs
The phenolic profile of walnut meal protein isolate and interaction of phenolics with walnut protein
期刊论文
OAI收割
FOOD RESEARCH INTERNATIONAL, 2023, 卷号: 170, 页码: 113042
作者:
Wang,Yuxi
;
Tan,Bing
;
Chen,Chi
;
Zhang,Xudong
;
Sun,Xiangjun
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/07/30
Walnut meal
Protein isolate
Phenolic compounds
Interaction mechanisms
Protein functional properties
AMINO-ACID-COMPOSITION
FUNCTIONAL-PROPERTIES
MOLECULAR DOCKING
ANTIOXIDANT ACTIVITY
BINDING INTERACTION
QUANTUM-MECHANICS
BETA-CASEIN
BIOACCESSIBILITY
HYDROLYSIS
PEPTIDES
A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency
期刊论文
OAI收割
CELL REPORTS, 2022, 卷号: 39, 期号: 10, 页码: 110928
作者:
Huang, Xin
;
Bashkenova, Nazym
;
Hong, Yantao
;
Lyu, Cong
;
Guallar, Diana
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/11/08
LONG NONCODING RNA
TET PROTEINS
ENHANCER ACTIVITY
CHROMATIN
BINDING
METHYLATION
PHASE
PLURIPOTENCY
PARASPECKLES
RECRUITMENT
Urinary galectin-3 binding protein (G3BP) as a biomarker for disease activity and renal pathology characteristics in lupus nephritis
期刊论文
OAI收割
ARTHRITIS RESEARCH & THERAPY, 2022, 卷号: 24, 期号: 1, 页码: 10
作者:
Ding, Huihua
;
Shen, Yiwei
;
Lin, Cheng
;
Qin, Ling
;
He, Shijun
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/06/15
Systemic lupus erythematosus
Lupus nephritis
Galectin-3 binding protein
Biomarker
Renal biopsy
Activity index
Design, synthesis, and antibacterial evaluation of vancomycin-LPS binding peptide conjugates
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 45, 页码: 8
作者:
Shi, Weiwei
;
Chen, Feifei
;
Zou, Xiangman
;
Jiao, Shang
;
Wang, Siqi
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/08/17
Vancomycin analogues
LPS binding peptides
Vancomycin-Peptide Conjugates
Antibacterial activity
Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963
作者:
Liu,Jiangxin
;
Wu,Xing-De
;
Li,Wenyan
;
Yuan,Zaifeng
;
Yang,Kun
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/04/02
Pseudolaric acid A
Hsp90 inhibitor
Apoptosis
NMR
Structure-activity relationship
Photoaffinity-based probe
Protein-ligand interaction
MOLECULAR CHAPERONE
PROTEIN
TARGET
CANCER
KINASE
NMR
IDENTIFICATION
SELECTIVITY
BINDING
DESIGN
Pnictogen, chalcogen, and halogen bonds in catalytic systems: theoretical study and detailed comparison
期刊论文
OAI收割
JOURNAL OF MOLECULAR MODELING, 2020, 卷号: 26, 期号: 1, 页码: 12
作者:
Lu, Ling
;
Lu, Yunxiang
;
Zhu, Zhengdan
;
Liu, Honglai
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
sigma-Hole interactions
Catalysis
Comparison
Binding strength
Activity
Influences of MgO(001) and TiO2(101) Supports on the Structures and Properties of Au Nanoclusters
期刊论文
OAI收割
CATALYSTS, 2020, 卷号: 10, 期号: 1, 页码: 11
作者:
Gao, Jinhua
;
Ren, Yuehong
;
Han, Qingzhen
;
Wen, Hao
;
Jiang, Zhaotan
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/05/21
Au nanoclusters
adsorption
binding energy
electronic structure
catalytic activity