中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
机构
采集方式
内容类型
发表日期
学科主题
筛选

浏览/检索结果: 共72条,第1-10条 帮助

条数/页: 排序方式:
Pharmacokinetics, mass balance, and metabolism of [14C]FCN-437c, a selective and potent CDK4/6 inhibitor in humans 期刊论文  OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2025, 卷号: 95, 期号: 1, 页码: 12
作者:  
Gao, Lei;  Ma, Sheng;  Yan, Shu;  Zhang, Hua;  Tian, Ling
  |  收藏  |  
Design and synthesis of CDK9/EZH2 dual-target inhibitors to achieve synergistic antitumor effects 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 14
作者:  
Tian, Lina;  Xiao, Jian;  Zeng, Yanping;  Li, Yangsha;  Wei, Aihuan
  |  收藏  |  
Fulcrum Occupancy-Leverage Perturbation Strategy Enables Rapid Discovery of Potent CDK2-Cyclin A2 Interaction Inhibitors 期刊论文  OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 14
作者:  
Sun, Ge;  Chi, Shuaishuai;  Li, Jiacheng;  Xu, Pan;  Lin, Tingting
  |  收藏  |  
Discovery of a ubiquitin-specific protease 10 inhibitor with high binding affinity promoting cell apoptosis via down-regulated CDK4 for the treatment of hepatocellular carcinoma 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 17
作者:  
Lu, Yang;  Wang, Wentao
  |  收藏  |  
Design, synthesis and bio-evaluation of 2,5-disubstituted thiazole derivatives for potential treatment of acute myeloid leukemia through targeting CDK9 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 160, 页码: 16
作者:  
Chen, Sumeng;  Huang, Jindi;  Zhang, Shipeng;  Zheng, Xinni;  Chen, Hongming
  |  收藏  |  
First ATG101-recruiting small molecule degrader for selective CDK9 degradation via autophagy-lysosome pathway 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 5, 页码: 2612-2624
作者:  
Zhong, Ye;  Xu, Jing;  Cao, Huiying;  Gao, Jie;  Ding, Shaoyue
  |  收藏  |  
Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradations 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 287, 页码: 10
作者:  
Zeng, Yanping;  Xiao, Jian;  Shi, Li;  Li, Yangsha;  Xu, Yuanxin
  |  收藏  |  
BET inhibitor and CDK4/6 inhibitor synergistically inhibit breast cancer by suppressing BRD4 stability and DNA damage repair 期刊论文  OAI收割
TRANSLATIONAL ONCOLOGY, 2025, 卷号: 51, 页码: 11
作者:  
Chi, Shuaishuai;  Wei, Fan;  Li, Yangsha;  Yu, Lei;  Ma, Chuyao
  |  收藏  |  
Unraveling the CDK9/PP2A/ERK Network in Transcriptional Pause Release and Complement Activation in KRAS-mutant Cancers 期刊论文  OAI收割
ADVANCED SCIENCE, 2024, 页码: 20
作者:  
Wang, Yafang;  Xu, Lansong;  Ling, Lijun;  Yao, Mingyue;  Shi, Shangxuan
  |  收藏  |  
Discovery of novel CDK9 inhibitor with tridentate ligand: Design, synthesis and biological evaluation 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 150, 页码: 12
作者:  
Zhong, Ye;  Xu, Jing;  Ding, Shaoyue;  Cao, Huiying;  Zhang, Yufei
  |  收藏  |