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浏览/检索结果: 共67条，第1-10条 帮助

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Design, synthesis and bio-evaluation of 2,5-disubstituted thiazole derivatives for potential treatment of acute myeloid leukemia through targeting CDK9 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 160, 页码: 16
作者:  Chen, Sumeng;  Huang, Jindi;  Zhang, Shipeng;  Zheng, Xinni;  Chen, Hongming
  |  收藏  |  浏览/下载：3/0  |  提交时间：2025/06/23
Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradations 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 287, 页码: 10
作者:  Zeng, Yanping;  Xiao, Jian;  Shi, Li;  Li, Yangsha;  Xu, Yuanxin
  |  收藏  |  浏览/下载：62/0  |  提交时间：2025/04/01
BET inhibitor and CDK4/6 inhibitor synergistically inhibit breast cancer by suppressing BRD4 stability and DNA damage repair 期刊论文  OAI收割
TRANSLATIONAL ONCOLOGY, 2025, 卷号: 51, 页码: 11
作者:  Chi, Shuaishuai;  Wei, Fan;  Li, Yangsha;  Yu, Lei
  |  收藏  |  浏览/下载：22/0  |  提交时间：2025/01/06
Unraveling the CDK9/PP2A/ERK Network in Transcriptional Pause Release and Complement Activation in KRAS-mutant Cancers 期刊论文  OAI收割
ADVANCED SCIENCE, 2024, 页码: 20
作者:  Wang, Yafang;  Xu, Lansong;  Ling, Lijun;  Yao, Mingyue;  Shi, Shangxuan
  |  收藏  |  浏览/下载：30/0  |  提交时间：2024/10/21
Discovery of novel CDK9 inhibitor with tridentate ligand: Design, synthesis and biological evaluation 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 150, 页码: 12
作者:  Zhong, Ye;  Xu, Jing;  Ding, Shaoyue;  Cao, Huiying;  Zhang, Yufei
  |  收藏  |  浏览/下载：23/0  |  提交时间：2024/08/22
Design, Synthesis, and Biological Evaluation of 2,4-Diaminopyrimidine Derivatives as Potent CDK7 Inhibitors 期刊论文  OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2024, 页码: 8
作者:  Zhang, Hualin;  Tu, Yutong;  Tao, Zhaofan;  Gao, Lixin;  Huang, Shengjie
  |  收藏  |  浏览/下载：18/0  |  提交时间：2024/08/22
The anticancer potential of chemical constituents of Moringa oleifera targeting CDK-2 inhibition in estrogen receptor positive breast cancer using in-silico and in vitro approches 期刊论文  OAI收割
BMC COMPLEMENTARY MEDICINE AND THERAPIES, 2023, 卷号: 23, 期号: 1, 页码: 17
作者:  Sultan, Rida;  Ahmed, Abrar;  Wei, Li;  Saeed, Hamid;  Islam, Muhammad
  |  收藏  |  浏览/下载：24/0  |  提交时间：2023/12/19
LINC00955 suppresses colorectal cancer growth by acting as a molecular scaffold of TRIM25 and Sp1 to Inhibit DNMT3B-mediated methylation of the PHIP promoter 期刊论文  OAI收割
BMC CANCER, 2023, 卷号: 23, 期号: 1, 页码: 20
作者:  Ren, Ganglin;  Li, Hongyan;  Hong, Dan;  Hu, Fangyu;  Jin, Rongjia
  |  收藏  |  浏览/下载：27/0  |  提交时间：2023/12/08
Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13
作者:  Hua, Chen;  Shena, Lijuan;  Zoua, Fengming;  Wua, Yun;  Wanga, Beilei
  |  收藏  |  浏览/下载：30/0  |  提交时间：2023/11/10
Discovery of HyT-Based Degraders of CDK9-Cyclin T1 Complex 期刊论文  OAI收割
CHEMISTRY & BIODIVERSITY, 2023, 页码: 10
作者:  Lin, Rongkun;  Yang, Jie;  Liu, Ting;  Wang, Mingyu;  Ke, Chongrong
  |  收藏  |  浏览/下载：44/0  |  提交时间：2023/10/17