中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
机构
采集方式
内容类型
发表日期
学科主题
筛选

浏览/检索结果: 共70条，第1-10条 帮助

条数/页： 排序方式：
Pharmacokinetics, mass balance, and metabolism of [14C]FCN-437c, a selective and potent CDK4/6 inhibitor in humans 期刊论文  OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2025, 卷号: 95, 期号: 1, 页码: 12
作者:  Gao, Lei;  Ma, Sheng;  Yan, Shu;  Zhang, Hua;  Tian, Ling
  |  收藏  |  浏览/下载：22/0  |  提交时间：2025/07/25
Design and synthesis of CDK9/EZH2 dual-target inhibitors to achieve synergistic antitumor effects 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 14
作者:  Tian, Lina;  Xiao, Jian;  Zeng, Yanping;  Li, Yangsha;  Wei, Aihuan
  |  收藏  |  浏览/下载：7/0  |  提交时间：2025/08/20
Design, synthesis and bio-evaluation of 2,5-disubstituted thiazole derivatives for potential treatment of acute myeloid leukemia through targeting CDK9 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 160, 页码: 16
作者:  Chen, Sumeng;  Huang, Jindi;  Zhang, Shipeng;  Zheng, Xinni;  Chen, Hongming
  |  收藏  |  浏览/下载：20/0  |  提交时间：2025/06/23
First ATG101-recruiting small molecule degrader for selective CDK9 degradation via autophagy-lysosome pathway 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 5, 页码: 2612-2624
作者:  Zhong, Ye;  Xu, Jing;  Cao, Huiying;  Gao, Jie;  Ding, Shaoyue
  |  收藏  |  浏览/下载：19/0  |  提交时间：2025/07/25
Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradations 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 287, 页码: 10
作者:  Zeng, Yanping;  Xiao, Jian;  Shi, Li;  Li, Yangsha;  Xu, Yuanxin
  |  收藏  |  浏览/下载：79/0  |  提交时间：2025/04/01
BET inhibitor and CDK4/6 inhibitor synergistically inhibit breast cancer by suppressing BRD4 stability and DNA damage repair 期刊论文  OAI收割
TRANSLATIONAL ONCOLOGY, 2025, 卷号: 51, 页码: 11
作者:  Chi, Shuaishuai;  Wei, Fan;  Li, Yangsha;  Yu, Lei;  Ma, Chuyao
  |  收藏  |  浏览/下载：35/0  |  提交时间：2025/01/06
Unraveling the CDK9/PP2A/ERK Network in Transcriptional Pause Release and Complement Activation in KRAS-mutant Cancers 期刊论文  OAI收割
ADVANCED SCIENCE, 2024, 页码: 20
作者:  Wang, Yafang;  Xu, Lansong;  Ling, Lijun;  Yao, Mingyue;  Shi, Shangxuan
  |  收藏  |  浏览/下载：37/0  |  提交时间：2024/10/21
Discovery of novel CDK9 inhibitor with tridentate ligand: Design, synthesis and biological evaluation 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 150, 页码: 12
作者:  Zhong, Ye;  Xu, Jing;  Ding, Shaoyue;  Cao, Huiying;  Zhang, Yufei
  |  收藏  |  浏览/下载：53/0  |  提交时间：2024/08/22
Design, Synthesis, and Biological Evaluation of 2,4-Diaminopyrimidine Derivatives as Potent CDK7 Inhibitors 期刊论文  OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2024, 页码: 8
作者:  Zhang, Hualin;  Tu, Yutong;  Tao, Zhaofan;  Gao, Lixin;  Huang, Shengjie
  |  收藏  |  浏览/下载：35/0  |  提交时间：2024/08/22
The anticancer potential of chemical constituents of Moringa oleifera targeting CDK-2 inhibition in estrogen receptor positive breast cancer using in-silico and in vitro approches 期刊论文  OAI收割
BMC COMPLEMENTARY MEDICINE AND THERAPIES, 2023, 卷号: 23, 期号: 1, 页码: 17
作者:  Sultan, Rida;  Ahmed, Abrar;  Wei, Li;  Saeed, Hamid;  Islam, Muhammad
  |  收藏  |  浏览/下载：38/0  |  提交时间：2023/12/19