中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [10]
合肥物质科学研究院 [2]
上海营养与健康研究所 [1]
采集方式
OAI收割 [13]
内容类型
期刊论文 [13]
发表日期
2025 [1]
2024 [2]
2023 [2]
2022 [1]
2021 [2]
2019 [2]
更多
学科主题
Biochemist... [1]
Biophysics [1]
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浏览/检索结果:
共13条,第1-10条
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Discovery of 2,4-quinazolinedione derivatives as LC3B recruiters in the facilitation of protein complex degradations
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 287, 页码: 10
作者:
Zeng, Yanping
;
Xiao, Jian
;
Shi, Li
;
Li, Yangsha
;
Xu, Yuanxin
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2025/04/01
LC3B
CDK9
Degradation
Protein complex
Unraveling the CDK9/PP2A/ERK Network in Transcriptional Pause Release and Complement Activation in KRAS-mutant Cancers
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 20
作者:
Wang, Yafang
;
Xu, Lansong
;
Ling, Lijun
;
Yao, Mingyue
;
Shi, Shangxuan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/10/21
KRAS
CDK9
ERK
complement activation
immunosuppression
Discovery of novel CDK9 inhibitor with tridentate ligand: Design, synthesis and biological evaluation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 150, 页码: 12
作者:
Zhong, Ye
;
Xu, Jing
;
Ding, Shaoyue
;
Cao, Huiying
;
Zhang, Yufei
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/08/22
CDK9
Inhibitor
Colorectal cancer
Apoptosis
Tridentate ligand
Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13
作者:
Hua, Chen
;
Shena, Lijuan
;
Zoua, Fengming
;
Wua, Yun
;
Wanga, Beilei
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/11/10
Acquired resistance mutations
CDK9 inhibitors
Transcription
Single nucleotide polymorphisms
BAY1251152
Discovery of HyT-Based Degraders of CDK9-Cyclin T1 Complex
期刊论文
OAI收割
CHEMISTRY & BIODIVERSITY, 2023, 页码: 10
作者:
Lin, Rongkun
;
Yang, Jie
;
Liu, Ting
;
Wang, Mingyu
;
Ke, Chongrong
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2023/10/17
CDK9
cyclin T1
degrader
hydrophobic tag
protein degradation
Inhibition of the dopamine transporter promotes lysosome biogenesis and ameliorates Alzheimer's disease-like symptoms in mice
期刊论文
OAI收割
ALZHEIMERS & DEMENTIA, 2022, 页码: 15
作者:
Yin, Limin
;
Zhou, Jianhui
;
Li, Tianyou
;
Wang, Xinghua
;
Xue, Wenlong
  |  
收藏
  |  
浏览/下载:91/0
  |  
提交时间:2022/11/11
Alzheimer's disease
CDK9
dopamine transporter
lysosome biogenesis
TFEB
Efficient Synthesis and Docking Analysis of Selective CDK9 Inhibitor NVP-2
期刊论文
OAI收割
Pharmaceutical Fronts, 2021, 期号: 3, 页码: E50-E55
作者:
Saidahmatov, Abdusaid
;
Liang, Xue-Wu
;
Shi, Yuqiang
;
Han, Xu
;
Liu, Hong
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/03/14
NVP-2
CDK9 inhitor
efficient synthesis
docking analysis
Discovery of selective CDK9 degraders with enhancing antiproliferative activity through PROTAC conversion
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 11
作者:
Qiu, Xiaqiu
;
Li, Yuanqing
;
Yu, Bin
;
Ren, Jie
;
Huang, Huidan
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/05/24
CDK9
Antitumor
PROTAC
AML
Degrader
Design of wogonin-inspired selective cyclin-dependent kinase 9 (CDK9) inhibitors with potent in vitro and in vivo antitumor activity
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 178, 页码: 782-801
作者:
Wang, Jubo
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/01
Wogonin
CDK9
AML
Flavonoid
Antitumor
CDK9 modulates circadian clock by attenuating REV-ERB alpha activity
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 513, 期号: 4, 页码: 967-973
作者:
Ou, Jiali
;
Li, Huilin
;
Tang, Yun-Chi
;
Qiu, Peiyuan
;
Li, Qing
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/12/09
Circadian clock
CDK9
BMAL1
REV-ERBa
PER2
Suprachiasmatic nucleus