中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [12]
昆明植物研究所 [2]
青岛生物能源与过程研... [2]
上海生物化学与细胞生... [2]
合肥物质科学研究院 [2]
生物物理研究所 [1]
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OAI收割 [26]
内容类型
期刊论文 [22]
会议论文 [2]
学位论文 [2]
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2025 [1]
2024 [1]
2022 [2]
2021 [4]
2020 [3]
2018 [1]
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Concurrent inhibition of p300/CBP and FLT3 enhances cytotoxicity and overcomes resistance in acute myeloid leukemia
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 14
作者:
Chen, Yu-jun
;
Zhao, Yu
;
Yao, Ming-yue
;
Wang, Ya-fang
;
Ma, Ming
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
acute myeloid leukemia
FLT3
p300/CBP
quizartinib resistance
combination strategy
基于系统动力学的西南边境人口集疏变化及动力机制研究
学位论文
OAI收割
中国科学院地理科学与资源研究所: 中国科学院大学, 2024
作者:
许冰洁
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/10/23
西南边境
人口集疏
系统动力学
CBP-SD 模型
Discovery of novel benzimidazole derivatives as potent p300 bromodomain inhibitors with anti-proliferative activity in multiple cancer cells
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 66, 页码: 16
作者:
Chen, Zonglong
;
Li, Jiayi
;
Yang, Hong
;
He, Yulong
;
Shi, Qiongyu
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2022/08/16
P300
Bromodomain inhibitors
CBP30
SBDD
Design, synthesis and biological evaluation of (R)-5-methylpyrrolidin-2-ones as p300 bromodomain inhibitors with Anti-Tumor activities in multiple tumor lines
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 124, 页码: 15
作者:
Liu, Ruiqi
;
Yang, Hong
;
Chen, Zonglong
;
Zhou, Kaixin
;
Shi, Qiongyu
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2022/08/16
Epigenetics
p300
CBP
Bromodomain inhibitors
CCS1477
Design, synthesis and biological evaluation of a novel spiro oxazolidinedione as potent p300/CBP HAT inhibitor for the treatment of ovarian cancer
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 52, 页码: 12
作者:
Ding, Hong
;
Pei, Yuan
;
Li, Yuanqing
;
Xu, Wen
;
Mei, Lianghe
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/06/15
Epigenetics
Histone acetyltransferase
P300/CBP
Ovarian cancer
A novel detection method applied on low-frequency harmonics of Tokamak power supply
期刊论文
OAI收割
ENERGY REPORTS, 2021, 卷号: 7
作者:
Tian, Yunxiang
;
Huang, Yiyun
;
Li, Jun
;
Yang, Shenfei
;
Mao, Huafeng
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/10
Harmonic detection
CBP-FIR filter
ICBP-FIR filter
Low-frequency harmonics
Tokamak power supply
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhou, Xiao-ru
;
Li, Xiao
;
Liao, Li-ping
;
Han, Jie
;
Huang, Jing
  |  
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2021/06/11
mantle cell lymphoma
idelalisib
drug resistance
P300
CBP
synergistic drug action
PI3Kδ
epigenetics
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhou, Xiao-ru
;
Li, Xiao
;
Liao, Li-ping
;
Han, Jie
;
Huang, Jing
  |  
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2021/06/11
mantle cell lymphoma
idelalisib
drug resistance
P300
CBP
synergistic drug action
PI3Kδ
epigenetics
Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7
作者:
Bi, Xiaoyang
;
Chen, Yu
;
Sun, Zhongya
;
Lu, Wenchao
;
Xu, Pan
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/05/24
Drug design
CBP
Bromodomain
Inhibitor
Acute myeloid leukemia
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:
Chen, Yu
;
Bi, Xiaoyang
;
Zhang, Fengcai
;
Sun, Zhongya
;
Xu, Pan
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/12/24
In silico screening
Drug design
CBP
Bromodomain
Inhibitor
Acute Myeloblastic Leukemia