中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
合肥物质科学研究院 [5]
化学研究所 [1]
上海药物研究所 [1]
采集方式
OAI收割 [7]
内容类型
期刊论文 [7]
发表日期
2024 [1]
2020 [2]
2018 [2]
2017 [1]
2016 [1]
学科主题
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Accelerating PROTACs Discovery Through a Direct-to-Biology Platform Enabled by Modular Photoclick Chemistry
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 12
作者:
Yan, Ke-Nian
;
Nie, Yong-Qiang
;
Wang, Jia-Yu
;
Yin, Guang-Liang
;
Liu, Qia
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/05/31
High-throughput chemical synthesis
modular synthesis
photoclick chemistry
PROTACs library
targeted protein degradation
Chemical protein synthesis-assisted high-throughput screening strategies for D-peptides in drug discovery
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31
作者:
Li, Ying
;
Cao, Xiuxiu
;
Tian, Changlin
;
Zheng, Ji-Shen
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/12/07
Chemical protein synthesis
Mirror-image proteins
Mirror-image phage display
Mirror-image one-bead one-compound (OBOC)
D-Peptide drug
Synthesis of Disulfide Surrogate Peptides Incorporating Large-Span Surrogate Bridges Through a Native-Chemical-Ligation-Assisted Diaminodiacid Strategy
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 卷号: 59
作者:
Qu, Qian
;
Gao, Shuai
;
Wu, Fangming
;
Zhang, Meng-Ge
;
Li, Ying
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/11/26
chemical protein synthesis
cyclic peptides
disulfides
native chemical ligation
peptides
Racemic X-ray structure of L-type calcium channel antagonist Calciseptine prepared by total chemical synthesis
期刊论文
OAI收割
SCIENCE CHINA-CHEMISTRY, 2018, 卷号: 61, 期号: 6, 页码: 702-707
作者:
Chen, Chen-Chen
;
Gao, Shuai
;
Ai, Hua-Song
;
Qu, Qian
;
Tian, Chang-Lin
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/08/23
protein chemical synthesis
calciseptine
hydrazide based native chemical ligation
racemic protein crystallography
Chemical synthesis and structural analysis of guanylate cyclase C agonist linaclotide
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2018, 卷号: 29
-
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/10/26
IRRITABLE-BOWEL-SYNDROME
RACEMIC PROTEIN CRYSTALLOGRAPHY
X-RAY STRUCTURES
GASTROINTESTINAL-TRACT
PREVALENCE
LIGATION
PATTERNS
IMPACT
Linaclotide
Guanylyl cyclase
Protein chemical synthesis
Fmoc solid phase peptide synthesis
Racemic crystallization
Chemical Synthesis of K34-Ubiquitylated H2B for Nucleosome Reconstitution and Single-Particle Cryo-Electron Microscopy Structural Analysis
期刊论文
OAI收割
CHEMBIOCHEM, 2017, 卷号: 18, 期号: 2, 页码: 176-180
作者:
Li, Jiabin
;
He, Qiaoqiao
;
Liu, Yuntao
;
Liu, Sanling
;
Tang, Shan
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2018/07/04
Cryo-electron Microscopy
Histone
Nucleosome
Protein Chemical Synthesis
Ubiquitylation
Small is Smarter: Nano MRI Contrast Agents - Advantages and Recent Achievements
期刊论文
OAI收割
SMALL, 2016, 卷号: 12, 期号: 5, 页码: 556-576
作者:
Gao, Zhenyu
;
Ma, Tiancong
;
Zhao, Enyu
;
Docter, Dominic
;
Yang, Wensheng
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2016/06/27
chemical synthesis
magnetic nanoparticles
protein coronas
surface modifications
tumor imaging