机构

• 上海药物研究所 [3]
• 生态环境研究中心 [3]
• 昆明植物研究所 [2]
• 上海生物化学与细胞生... [2]
• 长春应用化学研究所 [2]
• 化学研究所 [1]
• 更多

采集方式

• OAI收割 [15]
• iSwitch采集 [1]

内容类型

• 期刊论文 [16]

发表日期

• 2020 [2]
• 2018 [2]
• 2017 [1]
• 2014 [1]
• 2013 [1]
• 2012 [1]
• 更多

学科主题

• Biochemist... [1]
• Biochemist... [1]
• Oncology [1]

筛选

浏览/检索结果: 共16条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 New synthetic chitosan derivatives bearing benzenoid/heterocyclic moieties with enhanced antioxidant and antifungal activities 期刊论文  OAI收割 CARBOHYDRATE POLYMERS, 2020, 卷号: 249, 页码: 8 作者:  Mi, Yingqi;  Zhang, Jingjing;  Chen, Yuan;  Sun, Xueqi;  Tan, Wenqiang   |  收藏  |  浏览/下载：54/0  |  提交时间：2021/06/16 Carboxymethyl chitosan  Heterocyclic compounds  Antifungal activity  Antioxidant activity  Cytotoxicity assay   Cytotoxicity and genotoxicity assays of halobenzoquinones disinfection byproducts using different human cell lines 期刊论文  OAI收割 ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 2020, 卷号: 61, 期号: 5, 页码: 526-533 作者:  Li, Jiabao;  Zhang, Haifeng;  Han, Yingnan;  Chao, Huang;  Ma, Mei   |  收藏  |  浏览/下载：31/0  |  提交时间：2021/09/15 CCK-8 kit  chromosome damage  cytotoxicity  genotoxicity  HBQs  micronucleus (MN) assay   Application of a bacterial whole cell biosensor for the rapid detection of cytotoxicity in heavy metal contaminated seawater 期刊论文  OAI收割 CHEMOSPHERE, 2018, 卷号: 200, 页码: 322-329 作者:  Huang, Wei E.;  Davison, Paul A.;  Cui, Zhisong;  Jiang, Huichao;  Li, Qian   |  收藏  |  浏览/下载：42/0  |  提交时间：2019/06/21 Cytotoxicity  Heavy metal  Marine environment  Luminescent bacteria test assay  Mugilogobius chulae  Acinetobacter baylyi   Synthesis and Bioevaluation of Shikonin Derivatives 期刊论文  OAI收割 LETTERS IN DRUG DESIGN & DISCOVERY, 2018, 卷号: 15, 期号: 9, 页码: 945-950 作者:  Cao, Sufen;  Zhang, Jiangang;  Duan, Wenhu   |  收藏  |  浏览/下载：37/0  |  提交时间：2019/01/08 Amidation  chemical stability  cytotoxicity  esterification  shikonin derivatives  synthesis  SRB assay  cell lines   Design, synthesis and anti-HIV-1 RT evaluation of 2-(benzyl(4-chlorophenyl)amino)-1-(piperazin-1-yl)ethanone derivatives 期刊论文  OAI收割 Bioorganic & Medicinal Chemistry Letters, 2017, 卷号: 27, 期号: 1, 页码: 61-65 作者:  Chander S;  Pang W;  Sankaranarayanan M[*];  Ashok P;  Yang LM 收藏  |  浏览/下载：34/0  |  提交时间：2016/12/01 Enzymatic assay  Wild strain  Reverse transcriptase  Docking  Cytotoxicity   A facile method for detection of alkaline phosphatase activity based on the turn-on fluorescence of resorufin 期刊论文  OAI收割 analytical methods, 2014, 卷号: 6, 期号: 15, 页码: 6105-6109 Wang, Fangyuan; Li, Yongxin; Li, Wenying; Zhang,Qingfeng; Chen,Jian; Zhou,Huipeng; Yu,Cong 收藏  |  浏览/下载：33/0  |  提交时间：2015/10/21 ASCORBIC-ACID 2-PHOSPHATE  ALAMAR BLUE ASSAY  GOLD NANOPARTICLES  PERYLENE-PROBE  RESAZURIN  TIME  PYROPHOSPHATE  TETRAPHENYLETHYLENE  CYTOTOXICITY  AGGREGATION   Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文  OAI收割 PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299 作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju 收藏  |  浏览/下载：44/0  |  提交时间：2015/05/14 2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.   Neutral red based colorimetric microorganism bioassay for direct toxicity assessment of toxic chemicals in water 期刊论文  OAI收割 analytical methods, 2012, 卷号: 4, 期号: 11, 页码: 3849-3854 Zhai JF; Liu L; Yong DM; Li D; Dong SJ 收藏  |  浏览/下载：21/0  |  提交时间：2013/04/22 HEAVY-METAL TOXICITY  ESCHERICHIA-COLI  MEMBRANE DAMAGE  FLOW-CYTOMETRY  CELL VIABILITY  IN-VITRO  ASSAY  ADSORPTION  CYTOTOXICITY  INHIBITION   Synthesis of novel 6-triazologlycolipids via click chemistry and their preliminary cytotoxicity assessments 期刊论文  OAI收割 MOLECULAR DIVERSITY, 2011, 卷号: 15, 期号: 4, 页码: 889-900 作者:     |  收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 Glycolipid  Click reaction  Triazole  Cytotoxicity  MTT assay   Investigation on a potential targeting drug delivery system consisting of folate, mitoxantrone and human serum albumin 期刊论文  OAI收割 CHINESE JOURNAL OF CHEMISTRY, 2008, 卷号: 26, 期号: 8, 页码: 1385-1389 作者:  Zhou Qiu-Ju;  Bi Ya-Jing;  Xiang Jun-Feng;  Tang Ya-Lin;  Yang Qian-Fan   |  收藏  |  浏览/下载：14/0  |  提交时间：2019/04/09 Targeting Drug Delivery System  Mitoxantrone  Human Serum Albumin  Folate  Cytotoxicity Assay