机构

• 上海药物研究所 [5]
• 海洋研究所 [1]
• 天津工业生物技术研究... [1]

采集方式

• OAI收割 [7]

内容类型

• 期刊论文 [7]

发表日期

• 2018 [1]
• 2016 [2]
• 2015 [1]
• 2014 [1]
• 2013 [1]
• 2012 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共7条，第1-7条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Design, synthesis and biological evaluation of novel pyrimidinedione derivatives as DPP-4 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 12, 页码: 2131-2135 作者:  Li, Ning;  Wang, Li-Jun;  Jiang, Bo;  Guo, Shu-Ju;  Li, Xiang-Qian   |  收藏  |  浏览/下载：66/0  |  提交时间：2019/08/21 Pyrimidinedionederivatives  DPP-4 inhibitor  Molecular hybrid  SARs  Type 2 diabetes   OL3, a novel low-absorbed TGR5 agonist with reduced side effects, lowered blood glucose via dual actions on TGR5 activation and DPP-4 inhibition 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1359-1369 作者:  Ma, Shan-yao;  Ning, Meng-meng;  Zou, Qing-an;  Feng, Ying;  Ye, Yang-liang   |  收藏  |  浏览/下载：40/0  |  提交时间：2019/01/08 OL3  MN6  linagliptin  TGR5 agonist  DPP4 inhibitor  GLP-1  low-absorbed  gallbladder filling  type 2 diabetes mellitus   ol3anovellowabsorbedtgr5agonistwithreducedsideeffectsloweredbloodglucoseviadualactionsontgr5activationanddpp4inhibition 期刊论文  OAI收割 actapharmacologicasinica, 2016, 卷号: 000, 期号: 010, 页码: 1359 作者:  Ma Shanyao;  Ning Mengmeng;  Zou Qingan;  Feng Ying;  Ye Yangliang   |  收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01 OL3  MN6  linagliptin  TGR5 agonist  DPP4 inhibitor  GLP-1  low-absorbed  gallbladder filling  type 2 diabetes mellitus   Design, Synthesis, and Pharmacological Evaluation of Fused beta-Homophenylalanine Derivatives as Potent DPP-4 Inhibitors 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 6, 期号: 5, 页码: 602-606 作者:  Jiang, Tao;  Zhou, Yuren;  Chen, Zhuxi;  Sun, Peng;  Zhu, Jianming   |  收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 Diabetes  DPP-4 inhibitor  beta-homophenylalanine derivatives  sitagliptin   (R)-3-Amino-1-((3aS,7aS)-octahydro-1H-indol-1-yl)-4-(2,4,5-trifluorophenyl)butan-1-one derivatives as potent inhibitors of dipeptidyl peptidase-4: Design, synthesis, biological evaluation, and molecular modeling 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 23, 页码: 6684-6693 作者:  Wang, Sinan;  Su, Mingbo;  Wang, Jiang;  Li, Zeng;  Zhang, Lei   |  收藏  |  浏览/下载：111/0  |  提交时间：2019/01/08 DPP-4  Type 2 diabetes  Inhibitor  Binding mode  Oral bioavailability   Bioassay-Guided Isolation of DPP-4 Inhibitory Fractions from Extracts of Submerged Cultured of Inonotus obliquus 期刊论文  OAI收割 MOLECULES, 2013, 卷号: 18, 期号: 1, 页码: 1150-1161 作者:  Geng, Yan;  Lu, Zhen-Ming;  Huang, Wei;  Xu, Hong-Yu;  Shi, Jin-Song 收藏  |  浏览/下载：18/0  |  提交时间：2016/06/23 Inonotus obliquus  DPP-4 inhibitor  bioassay-guided isolation  UPLC-Q-TOF-MS  molecular docking   acuteandchronicadministrationofshr117887anovelandspecificdipeptidylpeptidase4inhibitorimprovesmetaboliccontrolindiabeticrodentmodels 期刊论文  OAI收割 actapharmacologicasinica, 2012, 卷号: 33, 期号: 8, 页码: 1013 作者:  Liu Xiao;  Zhang Lina;  Ying Feng;  Zhang Lei;  Qu Hui   |  收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01 GLUCAGON-LIKE PEPTIDE-1  IMPROVED GLUCOSE-TOLERANCE  DRUG-NAIVE PATIENTS  BETA-CELL FUNCTION  GLYCEMIC CONTROL  IV INHIBITOR  INSULIN-SECRETION  DOUBLE-BLIND  ZUCKER RATS  EFFICACY  SHR117887  vildagliptin (LAF237)  dipeptidyl peptidase-4 (DPP-4)  type 2 diabetes mellitus  glucagon-like peptide-1 (GLP-1)  insulin  beta-cells