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浏览/检索结果: 共2257条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Applications of innovative synthetic strategies in anticancer drug discovery: The driving force of new chemical reactions 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 119, 页码: 36 作者:  Wang, Han;  Ma, Xiaolong;  Sun, Longkang;  Bi, Tongyu;  Yang, Weibo   |  收藏  |  浏览/下载：31/0  |  提交时间：2025/04/01 Synthetic methodologies  Medicinal chemistry  New chemical reactions  Anticancer drug discovery   Current landscape of metal-organic framework-mediated nucleic acid delivery and therapeutics 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2025, 卷号: 672, 页码: 21 作者:  Feng, Shiwei;  Li, Yan;  Tan, Zheng;  Shen, Shiyang   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/04/01 Metal-organic frameworks  Nucleic acids  Nanocarrier  Drug delivery   Development of a bispecific antibody-drug conjugate targeting EpCAM and CLDN3 for the treatment of multiple solid tumors 期刊论文  OAI收割 EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2025, 卷号: 14, 期号: 1, 页码: 16 作者:  Luo, Meiying;  Wang, Xiaohuan;  Yu, Guoji;  Ji, Jing;  Li, Long   |  收藏  |  浏览/下载：12/0  |  提交时间：2025/04/07 EpCAM  CLDN3  Antibody-drug conjugate  Dxd  Solid tumor   IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response 期刊论文  OAI收割 EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2025, 卷号: 14, 期号: 1, 页码: 19 作者:  Yao, Mingyue;  Yan, Wenzhong;  Wang, Yafang;  Zhao, Yu;  Xu, Xiaowei   |  收藏  |  浏览/下载：5/0  |  提交时间：2025/04/01 Acute myeloid leukemia  HDAC inhibitor  FLT3-ITD mutation  DNA damage response  Synergistic effect  Drug resistance   Stimuli-Responsive Nano Drug Delivery Systems for the Treatment of Neurological Diseases 期刊论文  OAI收割 SMALL, 2025, 页码: 21 作者:  Dai, Xi-jian;  Li, Wen-Jia;  Xie, Dong-Dong;  Liu, Bi-xia;  Gong, Lianggeng   |  收藏  |  浏览/下载：8/0  |  提交时间：2025/04/01 drug release  nanomaterial  neurological diseases  stimulus-responsive nanodrug delivery system  targeted therapy   Proteomic Characterization of Liver Cancer Cells Treated with Clinical Targeted Drugs for Hepatocellular Carcinoma 期刊论文  OAI收割 BIOMEDICINES, 2025, 卷号: 13, 期号: 1, 页码: 20 作者:  Long, Hezhou;  Zhou, Jiafu;  Zhou, Changxia;  Xie, Shuyu;  Wang, Jingling   |  收藏  |  浏览/下载：5/0  |  提交时间：2025/04/01 proteomics  hepatocellular carcinoma  hepatocellular carcinoma-targeted drugs  S/T/Y phosphorylation  drug combination   Recent Development of Small Molecule Drugs for the Treatment of Osteoarthritis 期刊论文  OAI收割 PROGRESS IN CHEMISTRY, 2024, 卷号: 36, 期号: 12, 页码: 1849-1858 作者:  Zhang, Xiaofei;  Yang, Chunhao   |  收藏  |  浏览/下载：3/0  |  提交时间：2025/04/01 osteoarthritis  small molecule drugs  drug development   AlphaFold3 versus experimental structures: assessment of the accuracy in ligand-bound G protein-coupled receptors 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12 作者:  He, Xin-heng;  Li, Jun-rui;  Shen, Shi-yi;  Xu, H. Eric   |  收藏  |  浏览/下载：8/0  |  提交时间：2025/01/14 AlphaFold  structure-based drug design  artificial intelligence  GPCR  structural biology   Nanotechnology used for siRNA delivery for the treatment of neurodegenerative diseases: Focusing on Alzheimer's disease and Parkinson's disease 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2024, 卷号: 666, 页码: 15 作者:  Li, Yan;  Zhang, Jiahui;  Ma, Boqin   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/11/26 Neurodegenerative diseases  Brain drug delivery  Therapeutic drug  Small interfering RNA  Nanotechnology   Interaction-Based Inductive Bias in Graph Neural Networks: Enhancing Protein-Ligand Binding Affinity Predictions From 3D Structures 期刊论文  OAI收割 IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, 2024, 卷号: 46, 期号: 12, 页码: 8191-8208 作者:  Yang, Ziduo;  Zhong, Weihe;  Lv, Qiujie;  Dong, Tiejun;  Chen, Guanxing   |  收藏  |  浏览/下载：9/0  |  提交时间：2025/01/14 Proteins  Programmable logic arrays  Three-dimensional displays  Predictive models  Graph neural networks  Data models  Convolution  Protein-ligand binding affinity  graph neural networks  inductive bias  drug-target interaction  structure-based virtual screening