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Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [90]
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Applications of innovative synthetic strategies in anticancer drug discovery: The driving force of new chemical reactions
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 119, 页码: 36
作者:
Wang, Han
;
Ma, Xiaolong
;
Sun, Longkang
;
Bi, Tongyu
;
Yang, Weibo
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/04/01
Synthetic methodologies
Medicinal chemistry
New chemical reactions
Anticancer drug discovery
Synchrotron Radiation: A Key Tool for Drug Discovery
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 114, 页码: 10
作者:
Li, Fengcheng
;
Liu, Runze
;
Li, Wenjun
;
Xie, Mingyuan
;
Qin, Song
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/12/06
Synchrotron radiation
Drug discovery
Protein crystals
Structure determination
Ligand screening
Synchrotron Radiation: A Key Tool for Drug Discovery
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 114, 页码: 10
作者:
Li, Fengcheng
;
Liu, Runze
;
Li, Wenjun
;
Xie, Mingyuan
;
Qin, Song
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/12/06
Synchrotron radiation
Drug discovery
Protein crystals
Structure determination
Ligand screening
Recent Advances of Terpenoids with Intriguing Chemical Skeletons and Biological Activities
期刊论文
OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2024, 页码: 27
作者:
Zang, Yi
;
Sun, Ruo-nan
;
Feng, Ran-qi
;
Zhu, Hong-hui
;
Li, Xu-wen
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/12/25
Natural products
Terpenoids
Novel structures
Biological activity
Drug discovery
An updated patent review of SOS1 inhibitors (2022-present)
期刊论文
OAI收割
EXPERT OPINION ON THERAPEUTIC PATENTS, 2024, 页码: 15
作者:
Zhou, Guizhen
;
Zhou, Chuan
;
Ma, Xinyi
;
Xu, Jiahang
;
Zhou, Zehui
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/12/11
SOS1
KRAS
cancer
inhibitor
drug discovery
The application of nanodiscs in membrane protein drug discovery & development and drug delivery
期刊论文
OAI收割
FRONTIERS IN CHEMISTRY, 2024, 卷号: 12
作者:
Dong, Yingkui
;
Tang, Huan
;
Dai, Han
;
Zhao, Hongxin
;
Wang, Junfeng
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/11/20
nanodisc (ND)
membrane protein
drug discovery & development
drug delievery
membrane scaffold protein (MSP)
DockingGA: enhancing targeted molecule generation using transformer neural network and genetic algorithm with docking simulation
期刊论文
OAI收割
BRIEFINGS IN FUNCTIONAL GENOMICS, 2024, 页码: 12
作者:
Gao, Changnan
;
Bao, Wenjie
;
Wang, Shuang
;
Zheng, Jianyang
;
Wang, Lulu
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/05/20
molecule generation
molecule optimization
drug discovery
deep learning
drug design
genetic algorithm
A patent review of P2X7 receptor antagonists to treat inflammatory diseases (2018-present)
期刊论文
OAI收割
EXPERT OPINION ON THERAPEUTIC PATENTS, 2024, 卷号: 34
作者:
Iqbal, Jamshed
;
Bano, Sehrish
;
Khan, Imtiaz Ali
;
Huang, Qing
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/11/20
drug discovery
inflammation
heterocyclic compounds
calcium flux assay
Non-electrophysiological techniques targeting transient receptor potential (TRP) gene of gastrointestinal tract
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 卷号: 262, 页码: 17
作者:
Jiang, Yuting
;
Shen, Lan
;
Wang, Bing
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/05/07
Non-electrophysiological techniques
Transient receptor potential channels
Gastrointestinal tract
Drug discovery
Meta-MolNet: A Cross-Domain Benchmark for Few Examples Drug Discovery
期刊论文
OAI收割
IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS, 2024, 页码: 15
作者:
Lv, Qiujie
;
Chen, Guanxing
;
Yang, Ziduo
;
Zhong, Weihe
;
Chen, Calvin Yu-Chian
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/04/09
Benchmark platform
cross-domain meta-learning
drug discovery
few examples
Meta-MolNet
molecular property