机构

• 上海药物研究所 [10]
• 合肥物质科学研究院 [4]
• 金属研究所 [1]
• 化学研究所 [1]
• 西北高原生物研究所 [1]
• 大连化学物理研究所 [1]
• 更多

采集方式

• OAI收割 [18]

内容类型

• 期刊论文 [18]

发表日期

• 2021 [2]
• 2020 [3]
• 2019 [1]
• 2018 [1]
• 2017 [2]
• 2015 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共18条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 The genomic landscape of young and old lung cancer patients highlights age-dependent mutation frequencies and clinical actionability in young patients 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF CANCER, 2021 作者:  Cai, Lei;  Chen, Yong;  Tong, Xiaoling;  Wu, Xue;  Bao, Hua   |  收藏  |  浏览/下载：90/0  |  提交时间：2021/06/15 EGFR  ERBB2  gene fusions  tyrosine kinase inhibitors  young lung cancer patients   Computational Probing the Methylation Sites Related to EGFR Inhibitor-Responsive Genes 期刊论文  OAI收割 BIOMOLECULES, 2021, 卷号: 11, 期号: 7 作者:  Yuan, Rui;  Chen, Shilong;  Wang, Yongcui   |  收藏  |  浏览/下载：88/0  |  提交时间：2021/11/18 DNA methylation  group lasso  CTRP and CCLE  lung cancer  EGFR inhibitors effectiveness related methylation sites   2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidines as new reversible inhibitors of EGFR C797S (Cys797 to Ser797) mutant 期刊论文  OAI收割 CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 5, 页码: 1281-1287 作者:  Hu, Xianglong;  Xun, Qiuju;  Zhang, Tao;  Zhu, Su-Jie;  Li, Qian   |  收藏  |  浏览/下载：96/0  |  提交时间：2020/07/01 EGFR(C797S) mutant  SARs  2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidine  Clinical resistance  Fourth-generation inhibitors   Tumor Mutation Burden Correlates With Efficacy of Chemotherapy/Targeted Therapy in Advanced Non-Small Cell Lung Cancer 期刊论文  OAI收割 FRONTIERS IN ONCOLOGY, 2020, 卷号: 10 作者:  Lin, Chen;  Shi, Xun;  Zhao, Jun;  He, Qiong;  Fan, Yun   |  收藏  |  浏览/下载：78/0  |  提交时间：2020/10/26 tumor mutation burden (TMB)  clinical benefit  epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs)  chemotherapy  non-small cell lung cancer (NSCLC)   BBB-penetrating codelivery liposomes treat brain metastasis of non-small cell lung cancer with EGFR(T790M) mutation 期刊论文  OAI收割 THERANOSTICS, 2020, 卷号: 10, 期号: 14, 页码: 6122-6135 作者:  Yin, Weimin;  Zhao, Yuge;  Kang, Xuejia;  Zhao, Pengfei;  Zhao, Xuhong   |  收藏  |  浏览/下载：96/0  |  提交时间：2020/07/01 brain targeting delivery  tumor-associated macrophage  non-small cell lung cancer (NSCLC)  drug resistance  tyrosine kinase inhibitors (TKI)  EGFR T790M mutation   Synthesis and Biological Evaluation of Oxopyrido[2,3-d] Pyrimidine-7-ones Derivatives as Covalent L85812/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors 期刊论文  OAI收割 LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 8, 页码: 826-834 作者:  Niu, Ao   |  收藏  |  浏览/下载：79/0  |  提交时间：2020/07/01 Non-small cell lung cancer  irreversible inhibitors  EGFR(T79014)( )mutant  anti-tumor  xenograft model  cell proliferation   Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 298-306 作者:  Yan, Qi;  Chen, Yuzhe;  Tang, Baiyou;  Xiao, Qiang;  Qu, Rong   |  收藏  |  浏览/下载：84/0  |  提交时间：2019/01/08 EGFR inhibitors  Pyrimidine derivatives  Mutant selective inhibitors  AZD9291  T790M   Design, Synthesis, and Evaluation of Ribose-Modified Anilinopyrimidine Derivatives as EGFR Tyrosine Kinase Inhibitors 期刊论文  OAI收割 FRONTIERS IN CHEMISTRY, 2017, 卷号: 5 作者:  Hu, Xiuqin;  Wang, Disha;  Tong, Yi;  Tong, Linjiang   |  收藏  |  浏览/下载：70/0  |  提交时间：2019/01/08 EGFR  tyrosine kinase inhibitors  anilinopyrtmidine  glycosides  carbohydrate-based drugs   Discovery and characterization of a novel irreversible EGFR mutants selective and potent kinase inhibitor CHMFL-EGFR-26 with a distinct binding mode 期刊论文  OAI收割 ONCOTARGET, 2017, 卷号: 8, 期号: 11, 页码: 18359-18372 作者:  Hu, Chen;  Wang, Aoli;  Wu, Hong;  Qi, Ziping;  Li, Xixiang   |  收藏  |  浏览/下载：56/0  |  提交时间：2018/07/04 Egfr  Egfrt790m  Nsclc  Kinase Inhibitors  Drug Resistance   Discovery of Novel Tricyclic 5H-Pyridazino4,5-bindoles as Potent Antitumor Agents: Design, Synthesis and Biological Evaluation 期刊论文  OAI收割 CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2015, 卷号: 31, 期号: 3, 页码: 372-380 作者:  Zhai Xin;  Wang Limei;  Shi Jiyue;  Gong Ping   |  收藏  |  浏览/下载：57/0  |  提交时间：2021/02/02 TYROSINE KINASE INHIBITORS  GROWTH-FACTOR RECEPTOR  ANALOGS  DERIVATIVES  BINDING  HARMINE  1-Anilino-5H-pyridazino4,5-bindole  EGFR inhibitor  Cytotoxicity