中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [12]
昆明植物研究所 [2]
金属研究所 [1]
上海应用物理研究所 [1]
采集方式
OAI收割 [16]
内容类型
期刊论文 [15]
会议论文 [1]
发表日期
2023 [2]
2022 [3]
2021 [1]
2019 [1]
2015 [1]
2014 [1]
更多
学科主题
筛选
浏览/检索结果:
共16条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
Saikosaponin D improves nonalcoholic fatty liver disease via gut microbiota-bile acid metabolism pathway
期刊论文
OAI收割
Food Science and Human Wellness, 2023
作者:
Li, Lan
;
Yang, Shengye
;
Liang, Xinyu
;
Liu, Yameng
;
Xu, Hualing
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2024/03/26
Gut Microbiota
Non-alcoholic Fatty Liver Disease
Ssd
Bile Acids
Farnesoid x Receptor
Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii
期刊论文
OAI收割
PHYTOMEDICINE, 2023, 卷号: 121, 页码: 155054
作者:
Dai,Manyun
;
Peng,Wan
;
Lin,Lisha
;
Wu,Zhanxuan
;
Zhang,Ting
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/07/17
Intestinal bleeding
Triptolide
Celastrol
Intestinal FXR
Tripterygium wilfordii
FARNESOID-X-RECEPTOR
BACTERIAL TRANSLOCATION
ACTIVATION
INFLAMMATION
DYSFUNCTION
TRIPTOLIDE
MICROBIOTA
PREVENTS
OBESITY
MICE
Caffeic acid phenethyl ester suppresses intestinal FXR signaling and ameliorates nonalcoholic fatty liver disease by inhibiting bacterial bile salt hydrolase activity
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 12
作者:
Zhong, Xian-Chun
;
Liu, Ya-Meng
;
Gao, Xiao-Xia
;
Krausz, Kristopher W.
;
Niu, Bing
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/08/16
nonalcoholic fatty liver disease
caffeic acid phenethyl ester
bile salt hydrolase
farnesoid X receptor
ceramide
gut microbiota
Farnesoid X receptor (FXR) agonists induce hepatocellular apoptosis and impair hepatic functions via FXR/SHP pathway
期刊论文
OAI收割
ARCHIVES OF TOXICOLOGY, 2022, 页码: 15
作者:
Zhang, Tianwei
;
Feng, Shanshan
;
Li, Jiahuan
;
Wu, Zhitao
;
Deng, Qiangqiang
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/06/15
FXR agonist
Hepatotoxicity
Farnesoid X receptor
Obeticholic acid
Px-102
Apoptosis
Bile acid and receptors: biology and drug discovery for nonalcoholic fatty liver disease
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 17
作者:
Jiao, Ting-ying
;
Ma, Yuan-di
;
Guo, Xiao-zhen
;
Ye, Yun-fei
;
Xie, Cen
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/06/15
bile acids
nonalcoholic fatty liver disease
nonalcoholic steatohepatitis
drug target
Farnesoid X receptor
G protein-coupled bile acid receptor
FXR activation prevents liver injury induced by Tripterygium wilfordii preparations
期刊论文
OAI收割
XENOBIOTICA, 2021, 卷号: 51, 期号: 6, 页码: 716-727
作者:
Peng,Wan
;
Dai,Man-Yun
;
Bao,Li-Juan
;
Zhu,Wei-Feng
;
Li,Fei
  |  
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2022/04/02
Tripterygium wilfordii
liver injury
farnesoid X receptor
bile acid metabolism
metabolomics
Hepatocyte peroxisome proliferator-activated receptor alpha regulates bile acid synthesis and transport
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2019, 期号: 10, 页码: 1396-1411
作者:
Xie, Cen
;
Takahashi, Shogo
;
Brocker, Chad N.
;
He, Shijun
;
Chen, Li
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Peroxisome proliferator-activated receptor alpha
Wy-14,643
Bile acid homeostasis
Farnesoid X receptor
Metabolomics
Discovery of New Non-Steroidal Farnesoid X Receptor Modulators Through 3D Shape Similarity Search and Structure-Based Virtual Screening
期刊论文
OAI收割
CHEMICAL BIOLOGY & DRUG DESIGN, 2015, 卷号: 85, 期号: 4, 页码: 481-487
作者:
Wang, Lei
;
Si, Pei
;
Sheng, Yayun
;
Chen, Yingjie
;
Wan, Ping
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
farnesoid X receptor
modulators
similarity search
virtual screening
Synthesis and evaluation of (18) F-labeled bile acid compound: A potential PET imaging agent for FXR-related diseases
期刊论文
OAI收割
NUCLEAR MEDICINE AND BIOLOGY, 2014, 卷号: 41, 期号: 6, 页码: 495—500
Jia, LN
;
Jiang, DW
;
Hu, PC
;
Li, X
;
Shi, HC
;
Cheng, DF
;
Zhang, L
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2015/03/13
FARNESOID-X-RECEPTOR
NUCLEAR RECEPTOR
KNOCKOUT MICE
LIVER
ACTIVATION
HEPATOCARCINOGENESIS
CHOLESTASIS
EXPRESSION
INTESTINE
LIGANDS
Identification of 15d-PGJ(2) as an antagonist of farnesoid X receptor: Molecular modeling with biological evaluation
期刊论文
OAI收割
STEROIDS, 2013, 卷号: 78, 期号: 9, 页码: 813-822
作者:
Xu, Xing
;
Lul, Yin
;
Chen, Lili
;
Chen, Jing
;
Luo, Xiaomin
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
15-Deoxy-Delta(12,14)PGJ(2)
Farnesoid X receptor
Antagonist
Molecular dynamics simulation