中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共16条,第1-10条 帮助

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Saikosaponin D improves nonalcoholic fatty liver disease via gut microbiota-bile acid metabolism pathway 期刊论文  OAI收割
Food Science and Human Wellness, 2023
作者:  
Li, Lan;  Yang, Shengye;  Liang, Xinyu;  Liu, Yameng;  Xu, Hualing
  |  收藏  |  浏览/下载:45/0  |  提交时间:2024/03/26
Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii 期刊论文  OAI收割
PHYTOMEDICINE, 2023, 卷号: 121, 页码: 155054
作者:  
Dai,Manyun;  Peng,Wan;  Lin,Lisha;  Wu,Zhanxuan;  Zhang,Ting
  |  收藏  |  浏览/下载:9/0  |  提交时间:2024/07/17
Caffeic acid phenethyl ester suppresses intestinal FXR signaling and ameliorates nonalcoholic fatty liver disease by inhibiting bacterial bile salt hydrolase activity 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 12
作者:  
Zhong, Xian-Chun;  Liu, Ya-Meng;  Gao, Xiao-Xia;  Krausz, Kristopher W.;  Niu, Bing
  |  收藏  |  浏览/下载:36/0  |  提交时间:2022/08/16
Farnesoid X receptor (FXR) agonists induce hepatocellular apoptosis and impair hepatic functions via FXR/SHP pathway 期刊论文  OAI收割
ARCHIVES OF TOXICOLOGY, 2022, 页码: 15
作者:  
Zhang, Tianwei;  Feng, Shanshan;  Li, Jiahuan;  Wu, Zhitao;  Deng, Qiangqiang
  |  收藏  |  浏览/下载:59/0  |  提交时间:2022/06/15
Bile acid and receptors: biology and drug discovery for nonalcoholic fatty liver disease 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 17
作者:  
Jiao, Ting-ying;  Ma, Yuan-di;  Guo, Xiao-zhen;  Ye, Yun-fei;  Xie, Cen
  |  收藏  |  浏览/下载:32/0  |  提交时间:2022/06/15
FXR activation prevents liver injury induced by Tripterygium wilfordii preparations 期刊论文  OAI收割
XENOBIOTICA, 2021, 卷号: 51, 期号: 6, 页码: 716-727
作者:  
Peng,Wan;  Dai,Man-Yun;  Bao,Li-Juan;  Zhu,Wei-Feng;  Li,Fei
  |  收藏  |  浏览/下载:67/0  |  提交时间:2022/04/02
Hepatocyte peroxisome proliferator-activated receptor alpha regulates bile acid synthesis and transport 期刊论文  OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2019, 期号: 10, 页码: 1396-1411
作者:  
Xie, Cen;  Takahashi, Shogo;  Brocker, Chad N.;  He, Shijun;  Chen, Li
  |  收藏  |  浏览/下载:29/0  |  提交时间:2020/07/01
Discovery of New Non-Steroidal Farnesoid X Receptor Modulators Through 3D Shape Similarity Search and Structure-Based Virtual Screening 期刊论文  OAI收割
CHEMICAL BIOLOGY & DRUG DESIGN, 2015, 卷号: 85, 期号: 4, 页码: 481-487
作者:  
Wang, Lei;  Si, Pei;  Sheng, Yayun;  Chen, Yingjie;  Wan, Ping
  |  收藏  |  浏览/下载:28/0  |  提交时间:2019/01/08
Synthesis and evaluation of (18) F-labeled bile acid compound: A potential PET imaging agent for FXR-related diseases 期刊论文  OAI收割
NUCLEAR MEDICINE AND BIOLOGY, 2014, 卷号: 41, 期号: 6, 页码: 495—500
Jia, LN; Jiang, DW; Hu, PC; Li, X; Shi, HC; Cheng, DF; Zhang, L
收藏  |  浏览/下载:30/0  |  提交时间:2015/03/13
Identification of 15d-PGJ(2) as an antagonist of farnesoid X receptor: Molecular modeling with biological evaluation 期刊论文  OAI收割
STEROIDS, 2013, 卷号: 78, 期号: 9, 页码: 813-822
作者:  
Xu, Xing;  Lul, Yin;  Chen, Lili;  Chen, Jing;  Luo, Xiaomin
  |  收藏  |  浏览/下载:26/0  |  提交时间:2019/01/08