中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
大连化学物理研究所 [13]
上海药物研究所 [7]
中国科学院大学 [1]
采集方式
OAI收割 [20]
iSwitch采集 [1]
内容类型
期刊论文 [21]
发表日期
2022 [2]
2020 [1]
2018 [1]
2017 [2]
2016 [2]
2015 [5]
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学科主题
物理化学 [3]
Pharmacolo... [2]
Oncology [1]
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浏览/检索结果:
共21条,第1-10条
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Identification of naturally occurring inhibitors in Xian-Ling-Gu-Bao capsule against the glucuronidation of estrogens
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 17
作者:
He, Liangliang
;
Xu, Chunxia
;
Wang, Ziying
;
Duan, Shuyi
;
Xu, Jinjin
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/04/10
Xian-Ling-Gu-Bao capsule
estrogens
glucuronidation
inhibitory effects
UDP-glucuronosyltransferase
Intestinal Glucuronidation, Prior to Hepatic Glucuronidation, Plays an Important Role in the Low Circulating Levels of Calycosin
期刊论文
OAI收割
SEPARATIONS, 2022, 卷号: 9, 期号: 5, 页码: 15
作者:
Jiang, Haodong
;
Liu, Huan
;
Hu, Pei
;
Chen, Shuoji
;
Ye, Yaqing
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2022/08/16
calycosin
first-pass effect
intestinal glucuronidation
liver distribution
metabolism
Sulfation predominates the pharmacokinetics, metabolism, and excretion of forsythin in humans: major enzymes and transporters identified
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Pan, Lu-lu
;
Yang, Yong
;
Hui, Min
;
Wang, Shuo
;
Li, Cui-yun
  |  
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2020/12/24
forsythin
pharmacokinetics
drug metabolism
drug excretion
sulfation
glucuronidation
organic anion transporter 3
Identification and characterization of human UDP-glucuronosyltransferases responsible for xanthotoxol glucuronidation
期刊论文
OAI收割
XENOBIOTICA, 2018, 卷号: 48, 期号: 2, 页码: 109-116
作者:
Troberg, Johanna
;
Lv, Xia
;
Xia, Yang-Liu
;
Zhu, Liang-Liang
;
He, Guiyuan
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/06/20
Intestinal Glucuronidation
Udp-glucuronosyltransferases
Xanthotoxol
UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated?
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2017, 卷号: 14, 期号: 9, 页码: 2875-2883
作者:
Yang, Ling
;
Ge, Guang-Bo
;
Jarvinen, Erkka
;
Troberg, Johanna
;
Finel, Moshe
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2017/12/20
UDP-glucuronosyltransferase
recombinant UGT1A10
intestine microsomes
intestinal glucuronidation
estradiol
estrone
morphine
SN-38
AMC
NCHN
bavachinin
UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated?
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2017, 卷号: 14, 期号: 9, 页码: 2875-2883
作者:
Troberg, Johanna
;
Jarvinen, Erkka
;
Ge, Guang-Bo
;
Yang, Ling
;
Finel, Moshe
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2017/12/20
UDP-glucuronosyltransferase
recombinant UGT1A10
intestine microsomes
intestinal glucuronidation
estradiol
estrone
morphine
SN-38
AMC
NCHN
bavachinin
Methylation, Glucuronidation, and Sulfonation of Daphnetin in Human Hepatic Preparations In Vitro: Metabolic Profiling, Pathway Comparison, and Bioactivity Analysis
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL SCIENCES, 2016, 卷号: 105, 期号: 2, 页码: 808-816
作者:
Zhang, Jiang-Wei
;
He, Yu-Qi
;
Wang, Jia-Yue
;
Liang, Si-Cheng
;
Yang, Ling
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/06/20
Daphnetin
Methylation
Glucuronidation
Sulfonation
8-o-methyldaphnetin
Anti-inflammatory Activity
Methylation, glucuronidation, and sulfonation of daphnetin in human hepatic preparations in vitro: metabolic profiling, pathway comparison, and bioactivity analysis
期刊论文
iSwitch采集
Journal of pharmaceutical sciences, 2016, 卷号: 105, 期号: 2, 页码: 808-816
作者:
Liang, Si-Cheng
;
Xia, Yang-Liu
;
Hou, Jie
;
Ge, Guang-Bo
;
Zhang, Jiang-Wei
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/05/09
Daphnetin
Methylation
Glucuronidation
Sulfonation
8-o-methyldaphnetin
Anti-inflammatory activity
Glucuronidation of bavachinin by human tissues and expressed UGT enzymes: Identification of UGT1A1 and UGT1A8 as the major contributing enzymes
期刊论文
OAI收割
drug metabolism and pharmacokinetics, 2015, 卷号: 30, 期号: 5, 页码: 358-365
作者:
Lv, Xia
;
Hou, Jie
;
Xia, Yang-Liu
;
Ning, Jing
;
He, Gui-Yuan
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2015/11/17
Bavachinin
UDP-glucuronosyltransferases
UGT1A1
UGT1A8
Glucuronidation
Human tissues
In Vitro Evaluation of the Effect of 7-Methyl Substitution on Glucuronidation of Daphnetin: Metabolic Stability, Isoform Selectivity, and Bioactivity Analysis
期刊论文
OAI收割
journal of pharmaceutical sciences, 2015, 卷号: 104, 期号: 10, 页码: 3557-3564
作者:
Liang, Si-Cheng
;
Ge, Guang-Bo
;
Xia, Yang-Liu
;
Zhang, Jiang-Wei
;
Qi, Xiao-Yi
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2015/11/17
daphnetin
glucuronidation
methyl substitution
structural modification
metabolic stability
phase II enzymes
glucuronosyltransferases
human liver microsomes
enzyme kinetics
metabolic clearance