中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [20]
西北高原生物研究所 [10]
大连化学物理研究所 [2]
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OAI收割 [32]
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期刊论文 [31]
会议论文 [1]
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2022 [3]
2020 [2]
2019 [1]
2018 [2]
2017 [3]
2016 [11]
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Changes in Disposition of Ezetimibe and Its Active Metabolites Induced by Impaired Hepatic Function: The Influence of Enzyme and Transporter Activities
期刊论文
OAI收割
PHARMACEUTICS, 2022, 卷号: 14, 期号: 12, 页码: 22
作者:
Xie, Ningjie
;
Wang, Hong
;
Qin, Hua
;
Guo, Zitao
;
Xue, Hao
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
hepatic impairment
ezetimibe
active metabolites
phase II enzymes
transporters
first-pass metabolism
inhibitory bile acids
Mechanistic Study on the Species Differences in Excretion Pathway of HR011303 in Humans and Rats
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2022, 卷号: 50, 期号: 6, 页码: 809-818
作者:
Guo, Zitao
;
Liu, Mengling
;
Meng, Jian
;
Xue, Yaru
;
Huang, Qi
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/08/16
Molecular Basis Underlying Hepatobiliary and Renal Excretion of Phenolic Acids of Salvia miltiorrhiza Roots (Danshen)
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 13
作者:
Lu, Jun-Lan
;
Zeng, Xue-Shan
;
Zhou, Xin
;
Yang, Jun-Ling
;
Ren, Ling-Ling
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/08/16
Danshen
Salvia miltiorrhiza
phenolic acid
hepatic transporter
renal transporter
Sulfation predominates the pharmacokinetics, metabolism, and excretion of forsythin in humans: major enzymes and transporters identified
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Pan, Lu-lu
;
Yang, Yong
;
Hui, Min
;
Wang, Shuo
;
Li, Cui-yun
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/12/24
forsythin
pharmacokinetics
drug metabolism
drug excretion
sulfation
glucuronidation
organic anion transporter 3
Leflunomide increased the renal exposure of acyclovir by inhibiting OAT1/3 and MRP2
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 1, 页码: 129-137
作者:
Liao, Xiao-ying
;
Deng, Qiang-qiang
;
Han, Li
;
Wu, Zhi-tao
;
Peng, Zhao-liang
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
leflunomide
teriflunomide
acyclovir
organic anion transporter
multidrug resistance associated protein (MRP) 2
drug-drug interaction
pharmacokinetics
Effects on Expression of Hepatic Phase-1 and Phase-2 Metabolism and Transporter Genes by Swertia mussotii Extract, A Hepatoprotective Herb from Tibetan Traditional Medicine
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF AGRICULTURE AND BIOLOGY, 2019, 卷号: 21, 期号: 5
作者:
Yang, Hongxia
;
Xiao, Yuancan
;
Li, Cen
;
Gao, Tingting
;
Wei, Lixin
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2019/11/26
Tibetan traditional medicine
Swertia mussotii
Cytochrome P450
Hepatic transporters
Glycyrrhizin has a high likelihood to be a victim of drug-drug interactions mediated by hepatic organic anion-transporting polypeptide 1B1/1B3
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 17, 页码: 3486-3503
作者:
Dong, Jiajia
;
Olaleye, Olajide E.
;
Jiang, Rongrong
;
Li, Jing
;
Lu, Chuang
  |  
收藏
  |  
浏览/下载:96/0
  |  
提交时间:2019/01/08
Short-chain chlorinated paraffins (SCCPs) induced thyroid disruption by enhancement of hepatic thyroid hormone influx and degradation in male Sprague Dawley rats
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2018, 卷号: 625, 页码: 657-666
作者:
Gong, Yufeng
;
Zhang, Haijun
;
Geng, Ningbo
;
Xing, Liguo
;
Fan, Jingfeng
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2019/06/20
Short-chain Chlorinated Paraffins
Thyroid Disruption
Hepatic Metabolism
Thyroid Hormone
Constitutive Androstane Receptor
Increased Plasma Exposures of Conjugated Metabolites of Morinidazole in Renal Failure Patients: A Critical Role of Uremic Toxins
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2017, 卷号: 45, 期号: 6, 页码: 593-603
作者:
Kong, Fandi
;
Pang, Xiaoyan
;
Zhong, Kan
;
Guo, Zitao
;
Li, Xiuli
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2019/01/08
Salvia miltiorrhiza Roots against Cardiovascular Disease: Consideration of Herb-Drug Interactions
期刊论文
OAI收割
BIOMED RESEARCH INTERNATIONAL, 2017
作者:
Chen, Feng
;
Li, Li
;
Tian, Dan-Dan
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08